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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 1, 2001, Pages 81-86

Engineering of a functional human NADH-dependent cytochrome P450 system

(5) Döhr, Olaf a Paine, Mark J I a Friedberg, Thomas a Roberts, Gordon C K c Wolf, C Roland a,b

a UNIVERSITY OF DUNDEE (United Kingdom)

b UNIVERSITY OF DUNDEE (United Kingdom)

c UNIVERSITY OF LEICESTER (United Kingdom)

Author keywords

Ferredoxin reductase; Flavoproteins; Monooxygenases; NADPH cytochrome P450 reductase; Nitric oxide synthase

Indexed keywords

ALANINE; CYTOCHROME C; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; ETHOXYRESORUFIN; FERRICYANIDE; FLAVOPROTEIN; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRYPTOPHAN; UNSPECIFIC MONOOXYGENASE;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; GENETIC ENGINEERING; MICHAELIS CONSTANT; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BINDING SITES; CYTOCHROME C GROUP; ENZYME INHIBITORS; ESCHERICHIA COLI; FERRICYANIDES; HUMANS; KINETICS; MODELS, BIOLOGICAL; MUTATION; NAD; NADP; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXAZINES; PROTEIN BINDING; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY;

EID: 0035793117 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.98.1.81 Document Type: Article

Times cited : (75)

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