Heterologous over-expression of α-1,6-fucosyltransferase from Rhizobium sp.: Application to the synthesis of the trisaccharide β-D-GlcNAc(1 → 4)-[α-L-Fuc-(1 → 6)]-D-GlcNAc, study of the acceptor specificity and evaluation of polyhydroxylated indolizidines as inhibitors

Chemistry - A European Journal

Volumn 7, Issue 11, 2001, Pages 2390-2397

  Bastida, Agatha ^a   Fernández Mayoralas, Alfonso ^a   Gómez Arrayás, Ramón ^b   Iradier, Fatima ^b   Carretero, Juan Carlos ^b   García Junceda, Eduardo ^a  

^a INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Carbohydrates; Enzyme catalysis; Enzyme inhibitors; Glycosyltransferases; 1,6 fucosyltransferase

Indexed keywords

GENES; PURIFICATION; SUBSTRATES; SYNTHESIS (CHEMICAL);

GENE CODIFYING;

ENZYME INHIBITION;

CHITOSAN DERIVATIVE; FUCOSYLTRANSFERASE; INDOLIZIDINE DERIVATIVE; TRISACCHARIDE;

ARTICLE; CATALYSIS; ENZYME INDUCTION; ENZYME PURIFICATION; ENZYME SPECIFICITY; GENE AMPLIFICATION; HYDROXYLATION; MOLECULAR CLONING; NONHUMAN; PROTEIN EXPRESSION; RHIZOBIUM; SYNTHESIS;

ACETYLGLUCOSAMINIDASE; BACTERIAL PROTEINS; CATALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; ESCHERICHIA COLI; FUCOSYLTRANSFERASES; GENE EXPRESSION; INDOLIZINES; MAGNETIC RESONANCE IMAGING; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PLASMIDS; RECOMBINANT PROTEINS; RESTRICTION MAPPING; RHIZOBIUM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SWAINSONINE; TRISACCHARIDES;

EID: 0035354761     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20010601)7:11<2390::AID-CHEM23900>3.0.CO;2-0     Document Type: Article

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