-
2
-
-
0024273591
-
The role of the cytoeskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles
-
Lacey, E. The role of the cytoeskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. Int. J. Parasitol. 1988, 18, 885-890.
-
(1988)
Int. J. Parasitol.
, vol.18
, pp. 885-890
-
-
Lacey, E.1
-
3
-
-
0029793567
-
Synthesis and antimicrobial activity of some new piperidinil benzimidazoles
-
Kus, C.; Goker, H.; Ayhan, G.; Ertyan, R.; Altanlar, N.; Akin, A. Synthesis and antimicrobial activity of some new piperidinil benzimidazoles. Farmaco 1996, 51, 413-417.
-
(1996)
Farmaco
, vol.51
, pp. 413-417
-
-
Kus, C.1
Goker, H.2
Ayhan, G.3
Ertyan, R.4
Altanlar, N.5
Akin, A.6
-
4
-
-
0029866851
-
Synthesis of 1,2, 5,(6)-trisubstituted benzimidazoles and evaluation of their antimicrobial activities
-
Goker, H.; Tebrizli, E.; Abbasoglu, U. Synthesis of 1,2, 5,(6)-trisubstituted benzimidazoles and evaluation of their antimicrobial activities. Farmaco 1996, 51, 53-58.
-
(1996)
Farmaco
, vol.51
, pp. 53-58
-
-
Goker, H.1
Tebrizli, E.2
Abbasoglu, U.3
-
5
-
-
0029011094
-
Induction of chromosome loss in Saccharomyces cerevisiae strain D61.M by selected benzimidazole compounds
-
Going, C. J.; Mayer, V. W. Induction of chromosome loss in Saccharomyces cerevisiae strain D61.M by selected benzimidazole compounds. Mut. Res. 1995, 343, 185-199.
-
(1995)
Mut. Res.
, vol.343
, pp. 185-199
-
-
Going, C.J.1
Mayer, V.W.2
-
6
-
-
0018251153
-
Molecular Connectivity and substructure analysis
-
Hall, L.; Kier, L. Molecular Connectivity and substructure analysis. J. Pharm. Sci. 1978, 67, 1743-1747.
-
(1978)
J. Pharm. Sci.
, vol.67
, pp. 1743-1747
-
-
Hall, L.1
Kier, L.2
-
7
-
-
0029835371
-
Synthesis and antiviral evaluation of certain disubstituted benzimidazole ribonucleosides
-
Zou, R.; Ayres, K.; Drach J.; Townsend, L. Synthesis and antiviral evaluation of certain disubstituted benzimidazole ribonucleosides. J. Med. Chem. 1996, 39, 3477-3488.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 3477-3488
-
-
Zou, R.1
Ayres, K.2
Drach, J.3
Townsend, L.4
-
8
-
-
0030057371
-
Anti-HIV agents. IV. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H, 3H-thizolo-(3,4-a)benzimidazoles
-
Chimirri, A.; Grasso, S.; Molica, C.; Monforte, A.; Monforte, P.; Zappala, M.; Scopelliti, R. Anti-HIV agents. IV. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H, 3H-thizolo-(3,4-a)benzimidazoles. Farmaco 51,1996, 4, 279.
-
(1996)
Farmaco 51
, vol.4
, pp. 279
-
-
Chimirri, A.1
Grasso, S.2
Molica, C.3
Monforte, A.4
Monforte, P.5
Zappala, M.6
Scopelliti, R.7
-
9
-
-
0028793521
-
Studies on antiulcer agents: III. Plausible mechanism of antisecretory action of ethyl 2-((1H-benzimidazol-2-yl)sulfinylmethyl)-4-(dimetnylamino)-5-pyrimidinecar- boxylate, an H+/K+-ATPase inhibitor, based on its reaction with thiols
-
Terashima, K.; Muraoka, O.; Ono, M. Studies on antiulcer agents: III. Plausible mechanism of antisecretory action of ethyl 2-((1H-benzimidazol-2-yl)sulfinylmethyl)-4-(dimetnylamino)-5-pyrimidinecar- boxylate, an H+/K+-ATPase inhibitor, based on its reaction with thiols. Chem. Pharm. Bull. 1995, 43, 1985-1991.
-
(1995)
Chem. Pharm. Bull.
, vol.43
, pp. 1985-1991
-
-
Terashima, K.1
Muraoka, O.2
Ono, M.3
-
10
-
-
0030433833
-
Effects of newly synthesized benzimidazole derivatives on gastric H+/K+ATPase
-
Cheon, H. G.; Yum, E. K.; Kim, S. S. Effects of newly synthesized benzimidazole derivatives on gastric H+/K+ATPase. Arch. Pharm. Res. 1996, 19, 126-131.
-
(1996)
Arch. Pharm. Res.
, vol.19
, pp. 126-131
-
-
Cheon, H.G.1
Yum, E.K.2
Kim, S.S.3
-
11
-
-
0030040161
-
Potential anxiolytic agents. II. Improvement of oral efficacy for the pyrido(1,2-a)benzimidazole (PBI) class of GABA-A receptor modulators
-
Maryanoff, B.; McComsey, D.; Ho, W. Shank, R. P.; Dubinsky, B. Potential anxiolytic agents. II. Improvement of oral efficacy for the pyrido(1,2-a)benzimidazole (PBI) class of GABA-A receptor modulators. Bioorg Med. Chem. Lett. 1996, 6(3), 333.
-
(1996)
Bioorg Med. Chem. Lett.
, vol.6
, Issue.3
, pp. 333
-
-
Maryanoff, B.1
McComsey, D.2
Ho, W.3
Shank, R.P.4
Dubinsky, B.5
-
12
-
-
0029851014
-
Novel 5-hydroxytryptamine (5-HT-3) receptor antagonists, IV. Synthesys and pharmacological evaluation of the oxidation products of (-)-(R)-((1-methyl-1H-indol-3yl)carbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole hydrochloride (YM060: Ramosetron)
-
Ohta, M.; Suzuki, T.; Nagashima, S.; Tokunaga, T.; Miyata, K.; Mase, T. Novel 5-hydroxytryptamine (5-HT-3) receptor antagonists, IV. Synthesys and pharmacological evaluation of the oxidation products of (-)-(R)-((1-methyl-1H-indol-3yl)carbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole hydrochloride (YM060: Ramosetron). Chem. Pharm. Bull. 1996, 44, 1717-1722.
-
(1996)
Chem. Pharm. Bull.
, vol.44
, pp. 1717-1722
-
-
Ohta, M.1
Suzuki, T.2
Nagashima, S.3
Tokunaga, T.4
Miyata, K.5
Mase, T.6
-
13
-
-
0028183251
-
-
Bordi, F.; Mor, M.; Morini, G.; Plazzi, P. B.; Caretta, A. Farmaco 1994, 49, 153.
-
(1994)
Farmaco
, vol.49
, pp. 153
-
-
Bordi, F.1
Mor, M.2
Morini, G.3
Plazzi, P.B.4
Caretta, A.5
-
14
-
-
0027240392
-
Nonpeptide Angiotensin II receptor antagonists. Synthesis and biological activity of Benzimidazolecar-boxylic acids
-
Kuba, K.; Kohara, Y.; Imamiya, E.; Sugiura, Y.; Inada, Y.; Furukawa, Y.; Nishikawa, K.; Naka, T. Nonpeptide Angiotensin II receptor antagonists. Synthesis and biological activity of Benzimidazolecar-boxylic acids. J. Med. Chem. 1993, 36, 2182-2195.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 2182-2195
-
-
Kuba, K.1
Kohara, Y.2
Imamiya, E.3
Sugiura, Y.4
Inada, Y.5
Furukawa, Y.6
Nishikawa, K.7
Naka, T.8
-
15
-
-
0027327826
-
Nonpeptide Angiotensin II receptor antagonists. Synthesis and biological activity of potential prodrugs of Benzimidazole-7-carboxylic acids
-
Kubo, K.; Kohara, Y.; Yoshimura, Y.; Inada, Y.; Shibouta, Y.; Furukawa, Y.; Kato, T.; Nishikawa, K.; Naka, T. Nonpeptide Angiotensin II receptor antagonists. Synthesis and biological activity of potential prodrugs of Benzimidazole-7-carboxylic acids. J. Med. Chem. 1993, 36, 2343-2349.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 2343-2349
-
-
Kubo, K.1
Kohara, Y.2
Yoshimura, Y.3
Inada, Y.4
Shibouta, Y.5
Furukawa, Y.6
Kato, T.7
Nishikawa, K.8
Naka, T.9
-
16
-
-
0030480485
-
Synthesis and Angiotensin II receptor antagonists activities of benzimidazole derivatives bearing acidic heterocycles as novel tetrazole bioisosteres
-
Kohara, Y.; Kubo, K.; Imamiya, E.; Wada, T.; Inada, Y.; Naka, T. Synthesis and Angiotensin II receptor antagonists activities of benzimidazole derivatives bearing acidic heterocycles as novel tetrazole bioisosteres. J. Med. Chem. 1996, 39, 5228-5235.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 5228-5235
-
-
Kohara, Y.1
Kubo, K.2
Imamiya, E.3
Wada, T.4
Inada, Y.5
Naka, T.6
-
17
-
-
0027744344
-
6-Substituted benzimidazoles as a new nonpeptide Angiotensin II receptor antagonists: Synthesis, biological activity, and structure-activity relationships
-
Ries, U.; Mihm, G.; Narr, B.; Hasselbach, K.; Wittneben, H.; Entzeroth, M.; van Meel, J.; Wienen, W.; Hauel, N. 6-Substituted benzimidazoles as a new nonpeptide Angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships. J. Med. Chem. 1993, 36, 4040-4051.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 4040-4051
-
-
Ries, U.1
Mihm, G.2
Narr, B.3
Hasselbach, K.4
Wittneben, H.5
Entzeroth, M.6
Van Meel, J.7
Wienen, W.8
Hauel, N.9
-
18
-
-
0026509053
-
New nopeptide Angotensin II. 1. Synthesis, biological properties, and structure-activity relationships of 2-alkyl benzimidazole derivatives
-
Thomas, A.; Allott, C.; Gibson, K.; Major, J.; Masek, B.; Oldham, A.; Ratcliffe, H.; Roberts, D.; Russell, S.; Thomason, D. New nopeptide Angotensin II. 1. Synthesis, biological properties, and structure-activity relationships of 2-alkyl benzimidazole derivatives. J. Med. Chem. 1992, 35, 877-885.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 877-885
-
-
Thomas, A.1
Allott, C.2
Gibson, K.3
Major, J.4
Masek, B.5
Oldham, A.6
Ratcliffe, H.7
Roberts, D.8
Russell, S.9
Thomason, D.10
-
19
-
-
0025850476
-
Studies on the syntjesis of some 2-(1′-3′-benzodioxol-5′-yl)benzimidazole, benzothiazole, and benzoxazole derivatives
-
Isikdag, I.; Ucucu, U.; Ersan, S. Studies on the syntjesis of some 2-(1′-3′-benzodioxol-5′-yl)benzimidazole, benzothiazole, and benzoxazole derivatives. Gaz. Univ. Eczac. Fak. Derg. 1991, 8, 17-22.
-
(1991)
Gaz. Univ. Eczac. Fak. Derg.
, vol.8
, pp. 17-22
-
-
Isikdag, I.1
Ucucu, U.2
Ersan, S.3
-
20
-
-
0011927807
-
Synthesis and antiaggregant activity of N-substituted imidazole and benzimidazole derivatives
-
Scrgeeva, N.; Evstigneeva, R.; Rudko, L.; Kubatiev, A.; Shorshnev, S. Synthesis and antiaggregant activity of N-substituted imidazole and benzimidazole derivatives. Khim. Farm. Zhur. 1995, 29, 13-15.
-
(1995)
Khim. Farm. Zhur.
, vol.29
, pp. 13-15
-
-
Scrgeeva, N.1
Evstigneeva, R.2
Rudko, L.3
Kubatiev, A.4
Shorshnev, S.5
-
21
-
-
0030461967
-
Synthesis and evaluation of heterocyclic carboxamides as potential antypsychotic agents
-
(21 ) Norman, M. H.; Navas, F., III; Thomson, J. B.; Rigdon, G. C. Synthesis and evaluation of heterocyclic carboxamides as potential antypsychotic agents. J. Med. Chem. 1996, 39, 4692-4703.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4692-4703
-
-
Norman, M.H.1
Navas F. III2
Thomson, J.B.3
Rigdon, G.C.4
-
22
-
-
0011928488
-
Synthesis and pharmacological activity of 4-(2-dialkylaminoethyl)pyrrolo(1,2-a)benzimidazole salts
-
Anisimova, V.; Spasov, A.; Bocharova, I.; Ostrovskii, O.; Panchenko, T.; Dudchemko, G. Synthesis and pharmacological activity of 4-(2-dialkylaminoethyl)pyrrolo(1,2-a)benzimidazole salts. Khim. Farm. Zhur. 1996, 30, 20-25.
-
(1996)
Khim. Farm. Zhur.
, vol.30
, pp. 20-25
-
-
Anisimova, V.1
Spasov, A.2
Bocharova, I.3
Ostrovskii, O.4
Panchenko, T.5
Dudchemko, G.6
-
23
-
-
0001325629
-
Substituted 2.5′-Bi-1H-benzimidazoles: Topoisomerase I inhibition and cytotoxicity
-
Kim, J. S.; Gatto, B.; Yu, C.; Liu, A.; Liu, L. F.; Lavoie, E. J. Substituted 2.5′-Bi-1H-benzimidazoles: Topoisomerase I inhibition and cytotoxicity. J. Med. Chem. 1996, 39, 992-998.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 992-998
-
-
Kim, J.S.1
Gatto, B.2
Yu, C.3
Liu, A.4
Liu, L.F.5
Lavoie, E.J.6
-
24
-
-
0011999829
-
The Concept of Chemical Structure
-
Rouvray D., Ed.; J. Wiley and Sons: New York
-
Villaveces, J. L.; Daza, E. E. The Concept of Chemical Structure. In Concepts in Chemistry; Rouvray D., Ed.; J. Wiley and Sons: New York, 1997.
-
(1997)
Concepts in Chemistry
-
-
Villaveces, J.L.1
Daza, E.E.2
-
25
-
-
0033590783
-
Characterization and Comparison of Escherichia coli Tranfer-RNAs by Graph Theory based on Secondary Structure
-
Bermúdez, C. I.; Daza, E. E.; Andrade L. E. Characterization and Comparison of Escherichia coli Tranfer-RNAs by Graph Theory based on Secondary Structure. J. Theor. Biol. 1999, 197, 193-205.
-
(1999)
J. Theor. Biol.
, vol.197
, pp. 193-205
-
-
Bermúdez, C.I.1
Daza, E.E.2
Andrade, L.E.3
-
26
-
-
0003780715
-
-
Addison-Wesley: Reading, MA
-
Harary, H. Graph Theory, Addison-Wesley: Reading, MA, 1969.
-
(1969)
Graph Theory
-
-
Harary, H.1
-
28
-
-
33845378719
-
Applications of graph theory in chemistry
-
Balaban, A. Applications of graph theory in chemistry. J. Chem. Inf. Comput. Sci. 1985, 25, 334-343.
-
(1985)
J. Chem. Inf. Comput. Sci.
, vol.25
, pp. 334-343
-
-
Balaban, A.1
-
34
-
-
8644280181
-
On characterization of molecular branching
-
Randić, M. On characterization of molecular branching. J. Chem. Am. Soc. 1975, 97, 6609-6615.
-
(1975)
J. Chem. Am. Soc.
, vol.97
, pp. 6609-6615
-
-
Randić, M.1
-
35
-
-
0000805679
-
The Molecular Connectivity Chi Index and kappa Shape Indexes in Structure-Property Modeling
-
Lipkowitz, K., Boyd, D., Eds.; VCH: New York
-
Hall, L.; Kier, L. The Molecular Connectivity Chi Index and kappa Shape Indexes in Structure-Property Modeling. In Reviews in Computational Chemistry; Lipkowitz, K., Boyd, D., Eds.; VCH: New York, 1991; Vol. 2.
-
(1991)
Reviews in Computational Chemistry
, vol.2
-
-
Hall, L.1
Kier, L.2
-
38
-
-
0000981103
-
The Electron-Topological Approach To The Qsar Problem
-
Lipkovitz, K. P., Boyd, D. B., Eds.; VCH: New York
-
Bersurker, I. B.; Dimoglo, A. S. The Electron-Topological Approach To The Qsar Problem. In Reviews In Computational Chemistry; Lipkovitz, K. P., Boyd, D. B., Eds.; VCH: New York, 1991.
-
(1991)
Reviews In Computational Chemistry
-
-
Bersurker, I.B.1
Dimoglo, A.S.2
-
39
-
-
0002647913
-
Molecular Mechanics: The art and Science of Parametrization
-
Lipkowitz, K. Y., Boys, D., Eds.
-
Bowen, J. P.; Allinger, N. Molecular Mechanics: The art and Science of Parametrization. In Reviews in Computational Chemistry; Lipkowitz, K. Y., Boys, D., Eds.; 1991; Vol. 2.
-
(1991)
Reviews in Computational Chemistry
, vol.2
-
-
Bowen, J.P.1
Allinger, N.2
-
40
-
-
0004133516
-
-
Gaussian, Inc.: Pittsburgh, PA
-
Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Gill, P. M. W.; Johnson, B. G.; Robb, M. A.; Cheeseman, J. R.; Keith, T.; Petersson, G. A.; Montgomery, J. A.; Raghavachari, K.; Al-Laham, M. A.; Zakrzewski, V. G.; Ortiz, J. V.; Foresman, J. B.; Cioslowski, J.; Stefanov, B. B.; Nanayakkara, A.; Challacombe, M.; Peng, C. Y.; Ayala, P. Y.; Chen, W.; Wong, M. W.; Andres, J. L.; Replogle, E. S.; Gomperts, R.; Martin, R. L.; Fox, D. J.; Binkley, J. S.; Defrees, D. J.; Baker, J.; Stewart, J. P.; Head-Gordon, M.; Gonzalez, C.; Pople, J. A. Gaussian 94, revision D4; Gaussian, Inc.: Pittsburgh, PA, 1995.
-
(1995)
Gaussian 94, Revision D4
-
-
Frisch, M.J.1
Trucks, G.W.2
Schlegel, H.B.3
Gill, P.M.W.4
Johnson, B.G.5
Robb, M.A.6
Cheeseman, J.R.7
Keith, T.8
Petersson, G.A.9
Montgomery, J.A.10
Raghavachari, K.11
Al-Laham, M.A.12
Zakrzewski, V.G.13
Ortiz, J.V.14
Foresman, J.B.15
Cioslowski, J.16
Stefanov, B.B.17
Nanayakkara, A.18
Challacombe, M.19
Peng, C.Y.20
Ayala, P.Y.21
Chen, W.22
Wong, M.W.23
Andres, J.L.24
Replogle, E.S.25
Gomperts, R.26
Martin, R.L.27
Fox, D.J.28
Binkley, J.S.29
Defrees, D.J.30
Baker, J.31
Stewart, J.P.32
Head-Gordon, M.33
Gonzalez, C.34
Pople, J.A.35
more..
-
42
-
-
0024656378
-
A new method for the estimation of partition coefficient
-
Bodor, N.; Gabanyi, Z.; Wong, C. A new method for the estimation of partition coefficient. J. Am. Chem. Soc. 1989, 111, 3783-3786.
-
(1989)
J. Am. Chem. Soc.
, vol.111
, pp. 3783-3786
-
-
Bodor, N.1
Gabanyi, Z.2
Wong, C.3
-
43
-
-
0001728908
-
Quantum-chemical descriptors in QSAR-QSPR studies
-
and cited references
-
Karelson, M.; Lobanov, V.; Katritzky, A. Quantum-chemical descriptors in QSAR-QSPR studies. Chem. Rev. 1996, 96, 1027-1043, and cited references.
-
(1996)
Chem. Rev.
, vol.96
, pp. 1027-1043
-
-
Karelson, M.1
Lobanov, V.2
Katritzky, A.3
-
44
-
-
0001501582
-
The elctronic chemical potential and chemical hardness
-
Pearson, R. The elctronic chemical potential and chemical hardness. J. Mol. Struct. (THEOCHEM) 1992, 255, 261-270.
-
(1992)
J. Mol. Struct. (THEOCHEM)
, vol.255
, pp. 261-270
-
-
Pearson, R.1
-
45
-
-
85050554567
-
Chemometrics and Multivariate in Analytical Chemistry
-
Lipkowitz, K., Boyd, D., Eds.; VCH: New York
-
Jurs, P. C. Chemometrics and Multivariate in Analytical Chemistry. In Reviews in Computational Chemistry, Lipkowitz, K., Boyd, D., Eds.; VCH: New York, 1990: Vol. I.
-
(1990)
Reviews in Computational Chemistry
, vol.1
-
-
Jurs, P.C.1
-
46
-
-
0011927513
-
-
Ellis Horwood: New York
-
Brereton, R. Chemometrics; Ellis Horwood: New York, 1990.
-
(1990)
Chemometrics
-
-
Brereton, R.1
-
48
-
-
0342645323
-
Use of structure-activity data to compare structure-based clustering methods and descriptors for use in
-
Brown, R.; Martin, Y. Use of structure-activity data to compare structure-based clustering methods and descriptors for use in. J. Chem. Comput. Sci. 1996, 36, 572.
-
(1996)
J. Chem. Comput. Sci.
, vol.36
, pp. 572
-
-
Brown, R.1
Martin, Y.2
-
49
-
-
0026482141
-
Cardiotonic Agents. Synthesis and cardiovascular properties of novel 2-Arilbenzimidazoles and Azabenzimidazoles
-
Güngör, T.; Fouquet, A.; Teulon, J. M.; Provost, D.; Cazes, M.; Cloarec, A. Cardiotonic Agents. Synthesis and cardiovascular properties of novel 2-Arilbenzimidazoles and Azabenzimidazoles J. Med. Chem. 1992, 35, 4455-4463.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 4455-4463
-
-
Güngör, T.1
Fouquet, A.2
Teulon, J.M.3
Provost, D.4
Cazes, M.5
Cloarec, A.6
|