Synthesis and evaluation of heterocyclic carboxamides as potential antipsychotic agents

Journal of Medicinal Chemistry

Volumn 39, Issue 24, 1996, Pages 4692-4703

  Norman, Mark H ^a,b   Navas III, Frank ^a   Thompson, James B ^a   Rigdon, Greg C ^a  

^a GLAXOSMITHKLINE   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO N [4 [4 (1,2 BENZISOTHIAZOL 3 YL) 1 PIPERAZINYL]BUTYL]BENZAMIDE; APOMORPHINE; CLOZAPINE; HETEROCYCLIC AMINE; NEUROLEPTIC AGENT; RISPERIDONE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; EXTRAPYRAMIDAL SYMPTOM; MALE; NONHUMAN; PSYCHOSIS; RAT; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIPSYCHOTIC AGENTS; APOMORPHINE; BENZAMIDES; CLOZAPINE; HETEROCYCLIC COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; PIPERAZINES; RACLOPRIDE; RECEPTORS, DOPAMINE; RECEPTORS, SEROTONIN; RISPERIDONE; SALICYLAMIDES; THIAZOLES;

EID: 0030461967     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9603375     Document Type: Article

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