-
1
-
-
0033614446
-
Chronic Myeloid Leukemia
-
Sawyers, C. L. Chronic Myeloid Leukemia. N. Engl. J. Med. 1999, 340, 1330-1340.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
2
-
-
13044294682
-
An EvidenceBased Analysis of the Effect of Busulfan, Hydroxyurea, Interferon, and Allogeneic Bone Marrow Transplantation in Treating the Chronic Phase of Chronic Myeloid Leukemia: Developed for the American Society of Hematology see comments
-
Silver. R. T.; Woolf, S. H.; Hehlmann, R. Appelbaum, F. R.; Anderson, J.; Bennett, C. Goldman, J. M.; Guilhot, F.; Kantarjian, H. M. Lichtin, A. E.; Talpaz, M.; Tura, S. An EvidenceBased Analysis of the Effect of Busulfan, Hydroxyurea, Interferon, and Allogeneic Bone Marrow Transplantation in Treating the Chronic Phase of Chronic Myeloid Leukemia: Developed for the American Society of Hematology [see commentsJ. Blood 1999, 94, 1517-1536
-
(1999)
J. Blood
, vol.94
, pp. 1517-1536
-
-
Silver, R.T.1
Woolf, S.H.2
Hehlmann, R.3
Appelbaum, F.R.4
Anderson, J.5
Bennett, C.6
Goldman, J.M.7
Guilhot, F.8
Kantarjian, H.M.9
Lichtin, A.E.10
Talpaz, M.11
Tura, S.12
-
3
-
-
23444462074
-
Interferon alfa-2a as Compared with Conventional Chemotherapy for the Teatment of Chronic Myeloid Leukemia
-
The Italian Cooperative Study Group on Chronic Myeloid Leukemia. Interferon alfa-2a as Compared with Conventional Chemotherapy for the Teatment of Chronic Myeloid Leukemia. N. Engl. J. Med. 1994,330, 820-825
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 820-825
-
-
-
4
-
-
0030715606
-
Interferon alfa versus Chemotherapy for Chronic Myeloid Leukemia: A Meta-analysis of Seven Randomized Trials
-
Myeloid Leukemia Trialists1 Collaborative Group. Interferon alfa versus Chemotherapy for Chronic Myeloid Leukemia: A Meta-analysis of Seven Randomized Trials. J. Nail. Cancer Inst. 1997, 89, 1616-1620.
-
(1997)
J. Nail. Cancer Inst.
, vol.89
, pp. 1616-1620
-
-
-
5
-
-
0345696854
-
Interferon alfa-2b Combined with Cytarabine Versus Interferon Alone in Chronic Myelogenous Leukemia. French Chronic Myeloid Leukemia Study Group see comments
-
Guilhot, F.; Chastang, C.; Michallet, M.; Guerci, A.; Harousseau, J. L.; Maloisel, F., Bouabdallah, R.; Guyotat, D.; Cheron, N.; Nicolini, F.; Abgrall, J. F.; Tanzer, J. Interferon alfa-2b Combined with Cytarabine Versus Interferon Alone in Chronic Myelogenous Leukemia. French Chronic Myeloid Leukemia Study Group [see commentsJ. N. Engl. J. Med. 1997, 337, 223-229.
-
(1997)
J. N. Engl. J. Med.
, vol.337
, pp. 223-229
-
-
Guilhot, F.1
Chastang, C.2
Michallet, M.3
Guerci, A.4
Harousseau, J.L.5
Maloisel, F.6
Bouabdallah, R.7
Guyotat, D.8
Cheron, N.9
Nicolini, F.10
Abgrall, J.F.11
Tanzer, J.12
-
6
-
-
0000286732
-
A Minute Chromosome in Human Chronic Granulocytic Leukemia
-
Nowell, P. C.; Hungerford, D. A. A Minute Chromosome in Human Chronic Granulocytic Leukemia. Science 1960, 732, 1497-1501.
-
(1960)
Science
, vol.732
, pp. 1497-1501
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
7
-
-
0015694748
-
A new Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia Identified by Quinacrine Fluorescence and Giemsa Staining
-
Rowley, J. D. A new Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia Identified by Quinacrine Fluorescence and Giemsa Staining. Nature 1973,243, 290-293.
-
(1973)
Nature
, vol.243
, pp. 290-293
-
-
Rowley, J.D.1
-
8
-
-
0021802841
-
Fused Transcript of abl and bcr Genes in Chronic Myelogenous Leukaemia
-
Shtivelman, E.; Lifshitz, B.; Gale, R. P,; Canaani, E. Fused Transcript of abl and bcr Genes in Chronic Myelogenous Leukaemia. Nature 1985, 375, 550-554.
-
(1985)
Nature
, vol.375
, pp. 550-554
-
-
Shtivelman, E.1
Lifshitz, B.2
Gale, R.P.3
Canaani, E.4
-
9
-
-
0025348013
-
Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products
-
Lugo, T. G,; Pendergast, A. M,; Muller, A. J,; Witte, O. N. Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products. Science 1990, 247, 1079-1082.
-
(1990)
Science
, vol.247
, pp. 1079-1082
-
-
Lugo, T.G.1
Pendergast, A.M.2
Muller, A.J.3
Witte, O.N.4
-
10
-
-
0025117392
-
Induction of Chronic Myelogenous Leukemia in Mice by the p210bcr/abl gene of the Philadelphia Chromosome
-
Daley, G. Q,; Van Etten, R. A,; Baltimore, D. Induction of Chronic Myelogenous Leukemia in Mice by the p210bcr/abl gene of the Philadelphia Chromosome. Science 1990, 247, 824-830.
-
(1990)
Science
, vol.247
, pp. 824-830
-
-
Daley, G.Q.1
Van Etten, R.A.2
Baltimore, D.3
-
11
-
-
0025209916
-
Acute Leukaemia in bcr/abl Transgenic Mice
-
Heisterkamp, N.; Jenster, G.; ten Hoeve, J.; Zovich, D.; Pattengale, P. K.; Groffen, J. Acute Leukaemia in bcr/abl Transgenic Mice. Nature 1990,344, 251-253.
-
(1990)
Nature
, vol.344
, pp. 251-253
-
-
Heisterkamp, N.1
Jenster, G.2
Ten Hoeve, J.3
Zovich, D.4
Pattengale, P.K.5
Groffen, J.6
-
12
-
-
0034670036
-
The Molecular Biology of Chronic Myeloid Leukemia
-
Deininger, M. W.; Goldman, J. M.; Melo, J. V. The Molecular Biology of Chronic Myeloid Leukemia. Blood2000, 96, 3343-56.
-
(2000)
Blood
, vol.96
, pp. 3343-3356
-
-
Deininger, M.W.1
Goldman, J.M.2
Melo, J.V.3
-
13
-
-
0024240990
-
Blocking of EGF-Dependent Cell Proliferation by EOF Receptor Kinase Inhibitors
-
Yaish, P.; Gazit, A.; Gilon, C.; Levitzki, A. Blocking of EGF-Dependent Cell Proliferation by EOF Receptor Kinase Inhibitors. Science 1988, 242, 933-935.
-
(1988)
Science
, vol.242
, pp. 933-935
-
-
Yaish, P.1
Gazit, A.2
Gilon, C.3
Levitzki, A.4
-
14
-
-
0033987746
-
Lessons Learned from the Development of an abl Tyrosine Kinase Inhibitor for Chronic Myelogenous Leukemia
-
Druker, B. J.; Lydon, N. B. Lessons Learned from the Development of an abl Tyrosine Kinase Inhibitor for Chronic Myelogenous Leukemia. J. Clin. Invest. 2000, 705, 3-7.
-
(2000)
J. Clin. Invest.
, vol.705
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
15
-
-
0034665713
-
Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
-
Schindler, T.; Bornmann, W.; Pellicena, P.; Miller, W. T.; Clarkson, B.; Kuriyan, J. Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase. Science 2000,289, 1938-42.
-
(2000)
Science
, vol.289
, pp. 1938-1942
-
-
Schindler, T.1
Bornmann, W.2
Pellicena, P.3
Miller, W.T.4
Clarkson, B.5
Kuriyan, J.6
-
16
-
-
0029947186
-
Effects of a Selective Inhibitor of the Abi Tyrosine Kinase on the Growth of Bcr-Abl Positive Cells
-
Druker, B. J.; Tamura, S.; Buchdunger, E.; Ohno, S.; Segal, G. M.; Fanning, S.; Zimmermann, J.; Lydon, N. B. Effects of a Selective Inhibitor of the Abi Tyrosine Kinase on the Growth of Bcr-Abl Positive Cells. Nat. Med. 1996, 2, 561-566.
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Segal, G.M.5
Fanning, S.6
Zimmermann, J.7
Lydon, N.B.8
-
17
-
-
0030853063
-
The Tyrosine Kinase Inhibitor CGP57148B Selectively linhibits the Growth of BCR-ABL-Positive Cells
-
Deininger, M. W.; Goldman, J. M.; Lydon, N.; Melo, J. V. The Tyrosine Kinase Inhibitor CGP57148B Selectively linhibits the Growth of BCR-ABL-Positive Cells. Blood 1997, 90, 3691-3698.
-
(1997)
Blood
, vol.90
, pp. 3691-3698
-
-
Deininger, M.W.1
Goldman, J.M.2
Lydon, N.3
Melo, J.V.4
-
18
-
-
0032859309
-
Favorable Therapeutic Index of a p210(BCR-ABL)-Specific Tyrosine Kinase Inhibitor: Activity on LineageCommitted and Primitive Chronic Myelogenous Leukemia Progenitors
-
Kasper, B.; Fruehauf, S.; Schiedlmeier, B.; Buchdunger, E.; Ho, A. D.; Zeller, W. J. Favorable Therapeutic Index of a p210(BCR-ABL)-Specific Tyrosine Kinase Inhibitor: Activity on LineageCommitted and Primitive Chronic Myelogenous Leukemia Progenitors. Cancer Chemother. Pharmacol. 1999, 44, 433-438.
-
(1999)
Cancer Chemother. Pharmacol.
, vol.44
, pp. 433-438
-
-
Kasper, B.1
Fruehauf, S.2
Schiedlmeier, B.3
Buchdunger, E.4
Ho, A.D.5
Zeller, W.J.6
-
19
-
-
0031454003
-
CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TELPDGFR Fusion Proteins
-
Carroll, M.; Ohno-Jones, S.; Tamura, S.; Buchdunger, E.; Zimmermann, J.; Lydon, N. B.; Gilliland, D. G.; Druker, B. J. CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TELPDGFR Fusion Proteins. Blood 1997, 90, 4947-4952.
-
(1997)
Blood
, vol.90
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmermann, J.5
Lydon, N.B.6
Gilliland, D.G.7
Druker, B.J.8
-
20
-
-
15444350807
-
Selective Inhibition of Cell Proliferation and BCR-ABL Phosphorylation in Acute Lymphoblastic Leukemia Cells Expressing Mr 190,000 BCR-ABL Protein by a Tyrosine Kinase Inhibitor (CGP-57148)
-
Beran, M.; Cao, X.; Estrov, Z.; Jeha, S.; Jin, G.; O'Brien, S.; Talpaz, M.; Arlinghaus, R. B.; Lydon, N. B.; Kantarjian, H. Selective Inhibition of Cell Proliferation and BCR-ABL Phosphorylation in Acute Lymphoblastic Leukemia Cells Expressing Mr 190,000 BCR-ABL Protein by a Tyrosine Kinase Inhibitor (CGP-57148). Clin. Cancer Res. 1998, 4, 1661-1672.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 1661-1672
-
-
Beran, M.1
Cao, X.2
Estrov, Z.3
Jeha, S.4
Jin, G.5
O'Brien, S.6
Talpaz, M.7
Arlinghaus, R.B.8
Lydon, N.B.9
Kantarjian, H.10
-
21
-
-
0033585504
-
In Vivo Eradication of Human BCR/ABL-Positive Leukemia Cells with an ABL Kinase Inhibitor see commentsJ
-
le Coutre, P.; Mologni, L.; Cleris L; Marchesi, E.; Buchdunger, E.; Giardini, R.; Formelli, F.; Gambacorti-Passerini, C. In Vivo Eradication of Human BCR/ABL-Positive Leukemia Cells with an ABL Kinase Inhibitor [see commentsJ. J. Nail. Cancer Inst. 1999,97, 163-168.
-
(1999)
J. Nail. Cancer Inst.
, vol.97
, pp. 163-168
-
-
Coutre, P.1
Mologni, L.2
Cleris, L.3
Marchesi, E.4
Buchdunger, E.5
Giardini, R.6
Formelli, F.7
Gambacorti-Passerini, C.8
-
22
-
-
0000199137
-
Clinical Efficacy and Safety of an ABL Specific Tyrosine Kinase Inhibitor as Targeted Therapy for Chronic Myelogenous Leukemia
-
Druker, B. J.; Talpaz, M.; Resta, D.; Peng, B.; Buchdunger, E.; Ford, J.; Sawyers, C. L. Clinical Efficacy and Safety of an ABL Specific Tyrosine Kinase Inhibitor as Targeted Therapy for Chronic Myelogenous Leukemia. Blood Suppl. 1999.
-
(1999)
Blood Suppl.
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.3
Peng, B.4
Buchdunger, E.5
Ford, J.6
Sawyers, C.L.7
-
23
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker, B. J.; Talpaz, M.; Resta, D. J.; Peng, B.; Buchdunger, E.; Ford, J. M.; Lydon, N. B.; Kantarjian, H.; Capdeville, R.; Ohno-Jones, S.; Sawyers, C. L. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 2001,344, 1057.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1057
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
Ohno-Jones, S.10
Sawyers, C.L.11
-
24
-
-
0002501185
-
Activity of an Abl Specific Tyrosine Kinase Inhibitor in Patients with Bcr-Abl Positive Acute Leukemias, Including Chronic Myelogenous Leukemia in Blast Crisis
-
Talpaz, M.; Sawyers, C. L.; Kantarjian, H.; Resta, D.; Fernandes, Reese S, Ford, J.; Druker, B.J. Activity of an Abl Specific Tyrosine Kinase Inhibitor in Patients with Bcr-Abl Positive Acute Leukemias, Including Chronic Myelogenous Leukemia in Blast Crisis. Proc. Am. Soc. Clin. Ocol. 2000,19, 4a.
-
(2000)
Proc. Am. Soc. Clin. Ocol.
, vol.19
-
-
Talpaz, M.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.4
Fernandes Reese, S.5
Ford, J.6
Druker, B.J.7
-
25
-
-
0035810142
-
Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
-
in press
-
Druker, B. J.; Sawyers, C. L.; Kantarjian, H.; Resta, D. J.; Fernandas Reese, S.; Ford, J. M.; Capdeville, R.; Talpaz, M. Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome. N. Engl. J. Med. 2001, in press.
-
(2001)
N. Engl. J. Med.
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Fernandas Reese, S.5
Ford, J.M.6
Capdeville, R.7
Talpaz, M.8
-
26
-
-
0001368124
-
Clinical Pharmacokinetics and Pharmacodynamics of STI571 in a Phase 1 Trial in Chronic Myelogenous Leukemia (CML) Patients
-
Abstr. #
-
Peng, B., Hayes, M., Druker, B.Talpaz, M.; Sawyers, C.; Resta, D.; Ford, J.; Man, A. Clinical Pharmacokinetics and Pharmacodynamics of STI571 in a Phase 1 Trial in Chronic Myelogenous Leukemia (CML) Patients. Proc. Am. Assoc. Cancer Res. 2000, 41, Abstr. #3468.
-
(2000)
Proc. Am. Assoc. Cancer Res.
, vol.41
, pp. 3468
-
-
Peng, B.1
Hayes, M.2
Druker, B.3
Talpaz, M.4
Sawyers, C.5
Resta, D.6
Ford, J.7
Man, A.8
-
27
-
-
0001338423
-
Phase II Study of STI571, a Tyrosine Kinase Inhibitor, in Patients with Resistant or Refractory Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
-
Kantarajian, H.; Sawyers, C.; Hochhaus, A.; Guilhot, F.; Schiffer, C.; Resta, D.; Capdeville, R.; Druker, B. Phase II Study of STI571, a Tyrosine Kinase Inhibitor, in Patients with Resistant or Refractory Philadelphia Chromosome-Positive Chronic Myeloid Leukemia. Blood2000, 96, 470a.
-
(2000)
Blood
, vol.96
-
-
Kantarajian, H.1
Sawyers, C.2
Hochhaus, A.3
Guilhot, F.4
Schiffer, C.5
Resta, D.6
Capdeville, R.7
Druker, B.8
-
28
-
-
0001566710
-
Phase II Study of STI571 in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Accelerated Phase
-
Talpaz, M.; Silver, R. T.; Druker, B.; Paquette, R.; Goldman, J. M.; Reese, S. F.; Capdeville, R. A Phase II Study of STI571 in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Accelerated Phase. Blood 2000, 96, 469a.
-
(2000)
Blood
, vol.96
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.3
Paquette, R.4
Goldman, J.M.5
Reese, S.F.6
Capdeville, R.A.7
-
29
-
-
0000869570
-
A Phase II Study to Determine the Safety and Anti-Leukemic Effects of STI571 in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Myeloid Blast Crisis
-
Sawyers, C.; Hochhaus, A.; Feldman, E.; Goldman, J. M.; Miller, C.; Ben-Am, M.; Capdeville, R.; Druker, B. A Phase II Study to Determine the Safety and Anti-Leukemic Effects of STI571 in Patients with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Myeloid Blast Crisis. Blood 2000, 96, 503a.
-
(2000)
Blood
, vol.96
-
-
Sawyers, C.1
Hochhaus, A.2
Feldman, E.3
Goldman, J.M.4
Miller, C.5
Ben-Am, M.6
Capdeville, R.7
Druker, B.8
-
30
-
-
0034161460
-
Induction of Resistance to the Abelson Inhibitor STI571 in Human Leukemic Cells through Gene Amplification
-
le Coutre, P.; Tassi, E.; Varella-Garcia, M.; Bami, R.; Mologni, L.; Cabrita, G.; Marchesi, E.; Supino, R.; Gambacorti-Passerini, C. Induction of Resistance to the Abelson Inhibitor STI571 in Human Leukemic Cells Through Gene Amplification. Blood 2000, 95, 1758-1766.
-
(2000)
Blood
, vol.95
, pp. 1758-1766
-
-
Coutre, P.1
Tassi, E.2
Varella-Garcia, M.3
Bami, R.4
Mologni, L.5
Cabrita, G.6
Marchesi, E.7
Supino, R.8
Gambacorti-Passerini, C.9
-
31
-
-
0034254368
-
Selection and Characterization of BCR-ABL Positive Cell Lines with Differential Sensitivity to the Tyrosine Kinase Inhibitor STI571: Diverse Mechanisms of Resistance
-
Mahon, F. X.; Deininger, M. W.; Schultheis, B.; Chabrol, J.; Reiffers, J.; Goldman, J. M.; Mélo, J. V. Selection and Characterization of BCR-ABL Positive Cell Lines with Differential Sensitivity to the Tyrosine Kinase Inhibitor STI571: Diverse Mechanisms of Resistance. Blood 2000, 96, 10701079.
-
(2000)
Blood
, vol.96
, pp. 1070-1079
-
-
Mahon, F.X.1
Deininger, M.W.2
Schultheis, B.3
Chabrol, J.4
Reiffers, J.5
Goldman, J.M.6
Mélo, J.V.7
-
33
-
-
85086806541
-
Another Possible Mechanism of Resistance to STI571
-
Knight, Z. A. Another Possible Mechanism of Resistance to STI571. Blood 2000, 96, 4003-4005.
-
(2000)
Blood
, vol.96
, pp. 4003-4005
-
-
Knight, Z.A.1
-
34
-
-
0028142490
-
Crkl is the Major Tyrosine-Phosphorylated Protein in Neutrophils from Patients with Chronic Myelogenous Leukemia
-
Oda, T.; Heaney, C.; Hagopian, J. R.; Okuda, K.; Griffin, J. D.; Druker, B. J. Crkl is the Major Tyrosine-Phosphorylated Protein in Neutrophils from Patients with Chronic Myelogenous Leukemia. J. Biol. Chem. 1994, 269, 22925-22928.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22925-22928
-
-
Oda, T.1
Heaney, C.2
Hagopian, J.R.3
Okuda, K.4
Griffin, J.D.5
Druker, B.J.6
-
35
-
-
0001338426
-
Relapse in Ph+ Leukemia Patients with an Abl-Specific Kinase Inhibitor is Associated with Reactivation of Bcr-Abl
-
Gorre M, Banks K, Hsu NC, Monsour M, Rao NP, Ford JM, Paquette R, Sawyers CL. Relapse in Ph+ Leukemia Patients with an Abl-Specific Kinase Inhibitor is Associated with Reactivation of Bcr-Abl. Blood 2000, 96, 470a.
-
(2000)
Blood
, vol.96
-
-
Gorre, M.1
Banks, K.2
Hsu, N.C.3
Monsour, M.4
Rao, N.P.5
Ford, J.M.6
Paquette, R.7
Sawyers, C.L.8
-
36
-
-
0034330931
-
Efficacy of STI571, an Abl Tyrosine Kinase Inhibitor, in Conjunction with Other Antileukemic Agents Against Bcr-Abl-Positive Cells
-
Thiesing, J. T.; Ohno-Jones, S.; Kolibaba, K. S.; Druker, B. J. Efficacy of STI571, an Abl Tyrosine Kinase Inhibitor, in Conjunction with Other Antileukemic Agents Against Bcr-Abl-Positive Cells. Blood2000, 96, 3195-3199.
-
(2000)
Blood
, vol.96
, pp. 3195-3199
-
-
Thiesing, J.T.1
Ohno-Jones, S.2
Kolibaba, K.S.3
Druker, B.J.4
-
37
-
-
0034665903
-
CGP57148B (STI571) Induces Differentiation and Apoptosis and Sensitizes Bcr-Abl Positive Human Leukemia Cells to Apoptosis due to Antileukemic Drugs
-
Fang, G.; Kim, C. N.; Perkins, C. L.; Ramadevi, N.; Winton, E.; Wittmanri, Bhalla, K. N. CGP57148B (STI571) Induces Differentiation and Apoptosis and Sensitizes Bcr-Abl Positive Human Leukemia Cells to Apoptosis due to Antileukemic Drugs. Blood 2000, 96, 2246-2253.
-
(2000)
Blood
, vol.96
, pp. 2246-2253
-
-
Fang, G.1
Kim, C.N.2
Perkins, C.L.3
Ramadevi, N.4
Winton, E.5
Wittmanri, B.K.N.6
-
38
-
-
26744451709
-
Activity of the Farnesyl Transferase Inhibitor SCH66336 Against Bcr-Abl Induced Murine Leukemia, STI571 Resistant CML Cell Lines, and Primary Cells from CML Patients
-
Peters, D. G.; Hoover, R. R.; Yoh, E. Y.; Zhang, H.; Mahon, F. X.; Melo, J. V.; Kirschmeier, P.; Bishop, W. R.; Daley, G. Q. Activity of the Farnesyl Transferase Inhibitor SCH66336 Against Bcr-Abl Induced Murine Leukemia, STI571 Resistant CML Cell Lines, and Primary Cells from CML Patients. Blood 2000, 96, 510a.
-
(2000)
Blood
, vol.96
-
-
Peters, D.G.1
Hoover, R.R.2
Yoh, E.Y.3
Zhang, H.4
Mahon, F.X.5
Melo, J.V.6
Kirschmeier, P.7
Bishop, W.R.8
Daley, G.Q.9
-
39
-
-
0034254249
-
Inhibition of c-kit Receptor Tyrosine Kinase Activity by STI 571, a Selective Tyrosine Kinase Inhibitor
-
Heinrich, M. C.; Griffith, D. J.; Druker, B. J.; Wait, C. L.; Ott, K. A.; Zigler, A. J. Inhibition of c-kit Receptor Tyrosine Kinase Activity by STI 571, a Selective Tyrosine Kinase Inhibitor. Blood 2000, 96, 925-932.
-
(2000)
Blood
, vol.96
, pp. 925-932
-
-
Heinrich, M.C.1
Griffith, D.J.2
Druker, B.J.3
Wait, C.L.4
Ott, K.A.5
Zigler, A.J.6
-
40
-
-
15644363454
-
Gain-ofFunction Mutations of c-kit in Human Gastrointestinal Stromal Tumors
-
Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Tunio GM, Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y: Gain-ofFunction Mutations of c-kit in Human Gastrointestinal Stromal Tumors. Science 1998, 279, 577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
Tunio, G.M.11
Matsuzawa, Y.12
Kanakura, Y.13
Shinomura, Y.14
Kitamura, Y.15
-
41
-
-
0033883653
-
The Selective Tyrosine Kinase Inhibitor STI571 Inhibits Small Cell Lung Cancer Growth
-
Krystal, G. W.; Honsawek, S.; Litz, J.; Buchdunger, E. The Selective Tyrosine Kinase Inhibitor STI571 Inhibits Small Cell Lung Cancer Growth. Clin. Cancer Res. 2000, 6, 3319-3326.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3319-3326
-
-
Krystal, G.W.1
Honsawek, S.2
Litz, J.3
Buchdunger, E.4
-
42
-
-
0034691761
-
Growth Inhibition and Modulation of Kinase Pathways of Small Cell Lung Cancer Cell Lines by the Novel Tyrosine Kinase Inhibitor STI 571
-
Wang, W. L.; Healy, M. E.; Sattler, M.; Verma, S.; Lin, J.; Maulik, G.; Stiles, C. D.; Griffin, J. D.; Johnson, B. E.; Salgia, R. Growth Inhibition and Modulation of Kinase Pathways of Small Cell Lung Cancer Cell Lines by the Novel Tyrosine Kinase Inhibitor STI 571. Oncogene 2000,19, 3521-3528.
-
(2000)
Oncogene
, vol.19
, pp. 3521-3528
-
-
Wang, W.L.1
Healy, M.E.2
Sattler, M.3
Verma, S.4
Lin, J.5
Maulik, G.6
Stiles, C.D.7
Griffin, J.D.8
Johnson, B.E.9
Salgia, R.10
-
43
-
-
0034665138
-
Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class
-
Kilic, T.; Alberta, J. A.; Zdunek, P. R.; Acar, M.; lannarelli, P.; O'Reilly, T.; Buchdunger, E.; Black, P. M., Stiles, C. D. Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. Cancer Res. 2000, 60,5143-5150.
-
(2000)
Cancer Res.
, vol.60
, pp. 5143-5150
-
-
Kilic, T.1
Alberta, J.A.2
Zdunek, P.R.3
Acar, M.4
Lannarelli, P.5
O'Reilly, T.6
Buchdunger, E.7
Black, P.M.8
Stiles, C.D.9
|