Identification of a P2X7 receptor in GH4C1 rat pituitary cells: A potential target for a bioactive substance produced by Pfiesteria piscicida

Environmental Health Perspectives

Volumn 109, Issue 5, 2001, Pages 457-462

  Kimm Brinson, Karen L ^a   Moeller, Peter D R ^a   Barbier, Michéle ^a   Glasgow Jr , Howard ^b   Burkholder, JoAnn M ^b   Ramsdell, John S ^a  

^a CENTER FOR COASTAL ENVIRONMENTAL HEALTH AND BIOMOLECULAR RESEARCH   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

c fos; GH4C1; P2X7; Pfiesteria; Pituitary; Purinergic; Toxin

Indexed keywords

2',3' (4 BENZOYL)BENZOYLADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; AMINO ACID; LUCIFERASE; PROTEIN C FOS; PURINE P2X RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RECEPTOR SUBTYPE; TOXIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVITY; GENE CONSTRUCT; HYPOPHYSIS CELL; IMMUNOBLOTTING; IMMUNOREACTIVITY; NONHUMAN; ONCOGENE C FOS; OXIDATION; PFIESTERIA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALIA; PFIESTERIA; PFIESTERIA PISCICIDA; PROTOZOA;

EID: 0035325120     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109457     Document Type: Article

References (38)

1. Reporter gene assay for fish-killing activity produced by Pfiesteria piscicida
2. New "phantom" dinoflagellate is the causative agent of major estuarine fish kills
3. P. piscicida and P. piscicida-like dinoflagelletes: Behavioral impacts and environmental controls
4. Insidious effects of a toxic estuarine dinoflagellate on fish survival and human health
5. Implications of harmful marine microalgae and heterotrophic dinoflagellates in management of sustainable marine fisheries
6. Learning and memory difficulties after environmental exposure to waterways containing toxin-producing P. piscicida or P. piscicida-like dinoflagellates
7. Clonal strains of hormone-producing pituitary cells
8. 1 pituitary cells
9. 1 pituitary cells
10. Reporter gene assays for algal-derived toxins
11. 1 cells
12. In vitro detection methods for algal toxins: Conceptual approaches and recent developments
13. Trophic controls on stage transformation of a toxic ambush-predator dinoflagellate
14. The Biology and Impacts of Toxic P. piscicida Complex Species
15. Heteroduplex mobility assay guided sequence discovery: Elucidation of the small subunit (18S) rDNA sequence of Pfiesteria piscicida from complex algal culture and environmental sample DNA pools
16. PCR and FISH detection extends the range of Pfiesteria piscicida in estuarine waters
17. Tissue distribution of the P2X7 receptor
18. P2 purinoceptors: Historical perspective and classification
19. Receptors for purines and pyrimidines
20. Functional and molecular diversity of purinergic ion channel receptors
21. Oxidized ATP: An irreversible inhibitor of the macrophage purinergic P2Z receptor
22. Ionic effects on human recombinant P2X7 receptor function
23. ATP induces nucleotide permeability in mast cells
24. Mouse microglial cell express a plasma membrane pore gated by extracellular ATP
25. ATP4 permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes
26. The cytolitic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
27. Identification and characterization of an endogenous P2X7 (P2Z) receptor in CHO-K1 cells
28. Expression and transsynaptic regulation of P2X4 and P2Z receptors for extracellular ATP in parotid acinar cels
29. Pituitary cytokine and growth factor expression and action
30. Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line
31. Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages
32. The purinergic P2Z receptor of human macrophage cells. Characterization and possible physiological role
33. The P2Z purinoreceptor: An intriguing role in immunity, inflammation and cell death
34. Novel toxic dinoflagellete causes epidemic disease in esturarine fish
35. The P2Z/P2X7 receptor of microglial cells: A novel immunomodulatory receptor
36. Microglia: A sensor for pathological events in the CNS
37. Persistent learning deficits in rats after exposure to Pfiesteria piscicida