Cytokine kinetics in severe sepsis. Its relationship with mortality and organic dysfunction;Estudio de la cinética de citoquinas en sepsis grave y su relación con mortalidad y score de disfunción orgánica

Revista Medica de Chile

Volumn 129, Issue 4, 2001, Pages 347-358

  Dougnac L, Alberto ^a   Riquelme P, Arnoldo ^b   Calvo A, Mario ^b   Andresen H, Max ^b   Magedzo N, Amiram ^b   Eugeni, Eliseo ^b   Marshall R, Guillermo ^b   Gutiérrez T, Miguel ^b  

^a Rheumatology Service   (Chile)

^b NONE

Author keywords

Cytokines; Interleukin 6; Sepsis syndrome; Tumor necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

AGED; APACHE; ARTICLE; BLOOD; FEMALE; HOSPITALIZATION; HUMAN; MALE; METABOLISM; MORTALITY; MULTIPLE ORGAN FAILURE; PROSPECTIVE STUDY; SEPSIS; SEPTIC SHOCK; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

AGED; APACHE; CYTOKINES; FEMALE; HOSPITAL MORTALITY; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; MALE; MULTIPLE ORGAN FAILURE; PROSPECTIVE STUDIES; SEPSIS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035317253     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. BONE RC, BALK RA, CERRA FB, DELLINGER RP, FEIN AM, KNAUS WA, ET AL. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-74.
2. SCHLAG G, REDL H. Mediators of Injury and Inflammation. World J Surg 1996;20:406-10.
3. DAVIES M, HAGEN P. Systemic inflammatory response syndrome. British Journal of Surgery 1997;84:920-35.
4. SALVO I, DE CIAN W, MUSICCO M, LANGER M, PIADENA R, WOLFER A, ET AL. The Italian SEPSIS study: Preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock. Intensive Care Med 1995; 21: S244-S49.
5. PITTET D, RANGEL-FRAUSTO S, LI N, TARARA D, COSTIGAN M, REMPE L, ET AL. Systemic inflammatory response syndrome, sepsis, severe sepsis and septic shock: incidence, morbidities and outcomes in surgical ICU patients. Intensive Care Med 1995; 21: 302-9.
6. BONE RC, GRODZIN CJ, BALK RA. Sepsis: A New Hypothesis for Pathogenesis of the Disease Process. Chest 1997; 112: 235-43.
7. WAAGE A, HALSTENSEN A, ESPEVIK T. Association between tumor necrosis factor in serum and fatal outcome in patients with meningocociccal disease. Lancet 1987; 1: 355-57.
8. WAAGE A, BRANDTZAEG P, HALSTENSEN A, KIERULF P, ESPEVIK T. The complex pattern of cytokines in serum with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome. J Exp Med 1989; 169: 333-83.
9. DAMAS P, REUTER A, GYSEN P, DEMONTY J, LAMY M, FRANCHIMONT P. Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit Care Med. 1989; 17: 975-8.
10. DAMAS P, LEDOUX D, NYS M, VRINDTS Y, DE GROOTE D, FRANCHIMONT P, ET AL. Cytokine. Serum Level During Severe Sepsis in Human IL-6 as a Marker of Severity. Ann Surg 1992; 215:356-61.
11. PINSKY M, VINCENT J-L, DEVIERE J, ALEGRE M, KAHN R, DUPONT E. Serum Cytokine Levels in Human Septic Shock. Chest 1993; 103:565-75.
12. FRIEDLAND J, PORTER J, DARYANANI S, BLAND M, SCERATON N, VESELY M, ET AL. Plasma proinflamatory cytokine concentrations, Acute Physiology and Chronic Health Evaluation (APACHE) III scores and survival in patients in an intensive care unit. Crit Care Med 1996; 24:1775-81.
13. PRESTERL E, STAUDINGER T, PETTERMANN M, LASSNIGG A, BURGMANN H, WINKLER S, ET AL. Cytokine Profile and Correlation to the APACHE III and Scores in Patients with Sepsis. Am J Respir Crit Care Med 1997; 156:825-32.
14. DEBETS J, KAMPMEIJER R, VAN DER LINDEN M, BUURMAN W, VAN DER LINDEN C. Plasma tumor necrosis factor and mortality in critically ill septic patients. Crit Care Med 1989; 17:489-93.
15. MARECAUX G, PINSKY MR, DUPONT E, KAHN RJ, VINCENT JL. Blood lactate levels are better prognostic indicators than TNF or IL 6 levels in patients with septic shock. Intensive Care Med 1996; 22:404-08.
16. RICHE F, PANIS Y, LAISNE MJ, BRIARD C, CHOLLEY, BERNARD-POENARU O, ET AL. High tumor necrosis factor serum level is associated with increased survival in patients with abdominal septic shock: a prospective study in 59 patients. Surgery 1996; 120:801-07.
17. MARSHALL JC, COOK DJ, CHRISTOU NV, BERNARD G, SPRUNG C, SIBBALD W. Multiple Organ Dysfunction Score: A reliable descriptor of a complex clinical outcome. Crit Care Med 1995; 23: 1638-52.
18. KNAUS WA, DRAPER EA, WAGNER DP, ZIMMERMAN JE. APACHE II: a severity of disease classification system. Crit Care Med 1985; 13:818-29.
19. BONE RC. The pathogenesis of sepsis. Ann Intern Med 1991; 115:457-69
20. BONE RC. Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation. Crit Care Med 1996; 24:163-72.
21. PINSKY MR, MATUSCHAK GM. Multiple organ failure: Failure of host defense homeostasis. In:Multiple systems organ failure, Pinsky MR, Matuschak GM (Eds), Crit Care Clin 1989; 5: 199-220.
22. LESER HG, GROSS V, SCHEIBENBOGEN C, HEINISCH A, SALM R, LAUSEN M, ET AL. Elevation of serum Interleukin-6 concentration precedes acute phase response and reflects severity in Acute Pancreatitis. Gastroenterology 1991; 101:782-5.
23. STRUBER M, CREMER JT, GOHRBANDT B, HAGL C, JANKOWSKI M, VOLKER B, ET AL. Human cytokine responses to coronary artery bypass grafting and without cardiopulmonary bypass. Ann Thorac Surg 1999; 68:1330-5.
24. NAST-KOLB D, WAYDHAS C, GIPPNER-STEPPERT C, SCHNEIDER I, TRUPKA A, PUCHHOLTZ S, ET AL. Indicators of the posttraumatic inflammatory response correlate with organ failure in patients with multiple injuries. J Trauma 1997; 42:446-54.
25. PETEIRO-CARTELLE FJ, ALVAREZ J. Dynamic profiles of interleukin-6 and the soluble form of CD25 in burned patients. Burns 1999; 25: 487-91.
26. SCHRODER J, KAHLKE V, STAUBACH KH, ZABEL P, STUBER F. Gender differences in human sepsis. Arch Surg 1998; 133:1200-05.
27. VINCENT JL, DE MENDONCA A, CANTRAINE F, MORENO R, TAKALA J, SUTER PM, ET AL. Use of de SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med 1998; 26:1793-1800.
28. LE GALL JR, KLAR J, LEMESHOW S, SAULNIER F, ALBERTI C, ARTIGAS A, ET AL. The Logistic Organ Dysfunction System. A New way to assess Organ Dysfunction in the Intensive Care Unit. JAMA 1996; 276:802-10.
29. DOUGNAC A, ANGUS DC, HERNÁNDEZ G, OJEDA M, CASTRO J, ET AL. A tale of two scores: APACHE versus Marshall. Abst. Intensive Care Med 1996; 22: (Suppl 3) S272.
30. MUÑOZ C, CARLET J, FITTING C, MISSET B, BLERIOT JP, CAVAILLON JM. Dysregulation of in vitro cytokine production by monocytes during sepsis. J Clin Invest 1991; 88:1747-54.
31. SANCHEZ-CANTU L, RODE HN, CHRISTOU NV. Endotoxin tolerance is associated with reduced secretion of tumor necrosis factor. Arch Surg 1989; 124:1432-6.
32. HAAS JG, THIEL C, BLÖMER K, WEISS EH, RIETHMÜLLER G, ZIEGLER-HEITBROCK HW. Down regulation of tumor necrosis factor expression in human Mono-Mac-6 cell line by lipopolysaccharide. J Leukoc Biol 1989; 46:11-4.
33. FENTON MJ, CLARK BD, COLLINS KL, WEBB AC, RICH A, AURON PE. Transcriptional regulation of human prointerleukin 1β gene. J Immunol 1987; 138:3972-9.
34. ROGY MA, OLDENBURG HSA, COYLE S, TROUSDALE R, MOLDAWER L, LOWKY S. Correlation between Acute Physiology and Chronic Health Evaluation (APACHE) III score and immunological parameters in critically ill patients with sepsis. Br J Surg 1996; 83:396-400.
35. STRIETER R, KUNKEL S, BONE R. Role of tumor necrosis factor (in disease states and inflammation. Crit Care Med 1993;21:S447-S463.
36. BARRIERE SL, LOWRY SF. An overview of mortality risk prediction in sepsis. Crit Care Med 1995; 23: 376-93.
37. DINARELLO C, GELFAND J, WOLFF S. Anticytokine Strategies in the Treatment of the Systemic Inflammatory Response Syndrome. JAMA 1993; 269; 1829-35.
38. OBERHOLZER A, OBERHOLZER C, MOLDAWER L. Cytoquine signaling-regulation of the immune in normal and critically ill states. Crit Care Med 2000; 28 (suppl) N3-N12.
39. PATEL RT, DEEN KI, YOUNGS D, WARWICK J, KEIGHLEY MR. Interleukin 6 is a prognostic indicator of outcome in severe intra-abdominal sepsis. Br J Surg 1994; 81: 1306-8.
40. RANIERI VM, SUTER PM, TORTORELLA C, DE TULIO R, DAYER JM, BRIENZA A, ET AL. Effect of Mechanical Ventilation on inflammatory mediators in patients with Respiratory Distress Syndrome. A randomized controlled trial. JAMA 1999;282:54-61.