Costimulation of resting B lymphocytes alters the IL-4-activated IRS2 signaling pathway in a STAT6 independent manner: Implications for cell survival and proliferation

Cell Research

Volumn 11, Issue 1, 2001, Pages 44-54

  Zamorano, Jose ^a,b   Kelly, Ann E ^a   Austrian, Jonathan ^a   Wang, Helen Y ^a   Keegan, Achsah D ^a  

^a HOLLAND LABORATORY   (United States)

^b Hospital San Pedro de Alcantara   (Brazil)

Author keywords

B lymphocytes; IL 4; Proliferation; Survival

Indexed keywords

CD40 LIGAND; ENZYME INHIBITOR; GRB2 PROTEIN, MOUSE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INSULIN RECEPTOR SUBSTRATE 2 PROTEIN; INSULIN RECEPTOR SUBSTRATE-2 PROTEIN; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MAP2K1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STAT6 PROTEIN; STAT6 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL DIVISION; CELL SURVIVAL; DRUG EFFECT; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; B-LYMPHOCYTES; CD40 LIGAND; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; ENZYME INHIBITORS; GRB2 ADAPTOR PROTEIN; INTERLEUKIN-4; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MAP KINASE KINASE 1; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

EID: 0035287190     PISSN: 10010602     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cr.7290065     Document Type: Article

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