Pulmonary endothelinergic system in experimental congestive heart failure

Cardiovascular Research

Volumn 49, Issue 2, 2001, Pages 330-339

  Lepailleur Enouf, Delphine ^a   Egidy, Giorgia ^a   Philippe, Monique ^a   Louedec, Liliane ^a   Henry, Jean Paul ^a   Mulder, Paul ^a   Michel, Jean Baptiste ^a  

^a INSERM   (France)

Author keywords

Endothelins; Gene expression; Heart failure; Receptors

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONGESTIVE HEART FAILURE; CORONARY ARTERY LIGATION; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE; HYPOTHESIS; LUNG ENDOTHELIUM; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SKELETAL MUSCLE;

ANALYSIS OF VARIANCE; ANIMALS; AORTA; ASPARTIC ENDOPEPTIDASES; ENDOTHELIN-1; ENDOTHELINS; GENE EXPRESSION; HEART FAILURE, CONGESTIVE; HEART VENTRICLES; LUNG; MALE; METALLOENDOPEPTIDASES; MUSCLE, SKELETAL; ORGAN CULTURE TECHNIQUES; PLEURAL EFFUSION; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; RNA, MESSENGER;

EID: 0035254542     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00264-9     Document Type: Article

References (45)

1. Diminished endothelium-derived relaxing factor activity in an experimental model of chronic heart failure
2. Hemodynamic stresses induce endothelial dysfunction and remodeling of pulmonary artery in experimental compensated heart failure
3. Discrepancy between plasma and lung angiotensin-converting enzyme activity in experimental congestive heart failure. A novel aspect of endothelium dysfunction
4. Atrial natriuretic factor influences in vivo plasma, lung and aortic wall cGMP concentrations differently
5. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
6. Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart
7. Endothelin in human congestive heart failure
8. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure
9. Role of endogenous endothelin in chronic heart failure: Effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling
10. Selective ETA receptor blockade prevents left ventricular remodeling and deterioration of cardiac function in experimental heart failure
11. Human pulmonary circulation is an important site for both clearance and production of endothelin-1
12. Experimental myocardial infarction in the rat: Qualitative and quantitative changes during pathologic evolution
13. Hormonal and cardiac effects of converting enzyme inhibition in rat myocardial infarction
14. Myocardial infarct size and ventricular function in rats
15. Increased ANF secretion after volume expansion is preserved in rats with heart failure
16. Transcriptional regulation of the gene encoding the major surfactant protein (SP-A) in rabbit fetal lung
17. Glucocorticosteroids increase beta 2-adrenergic receptor transcription in human lung
18. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
19. Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells
20. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene
21. Increased endothelin expression in a rat cardiac allograft model of chronic vascular rejection
22. Construction, expression and characterization of a soluble form of human endothelin-converting-enzyme-1
23. Why are circulating concentrations of endothelin-1 so low?
24. Discrepancy between plasma and aortic wall cyclic guanosine monophosphate in an experimental model of congestive heart failure
25. Pulmonary hypertension caused by congestive heart failure is ameliorated by long-term application of an endothelin receptor antagonist. Increased expression of endothelin-1 messenger ribonucleic acid and endothelin-1-like immunoreactivity in the lung in congestive heart failure in rats
26. Pulmonary and cardiac expression of preproendothelin-1 mRNA are increased in heart failure after myocardial infarction in rats. Localization of preproendothelin-1 mRNA and endothelin peptide
27. Increased cardiac and pulmonary endothelin-1 mRNA expression in canine pacing-induced heart failure
28. Regulation of endothelin-1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP
29. 2+ and protein kinase C in shear stress-induced actin depolymerization and endothelin-1 gene expression
30. Hemodynamic shear stress stimulates endothelin production by cultured endothelial cells
31. Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium
32. Presence of non-selective type of endothelin receptor on vascular endothelium and its linkage to vasodilation
33. ETB-mediated regulation of extracellular levels of endothelin-1 in cultured human endothelial cells
34. Clearance of circulating endothelin-1 by ETB receptors in rats
35. Pulmonary clearance of circulating endothelin-1 in dogs in vivo: Exclusive role of ETB receptors
36. Level of ETB receptor mRNA is down-regulated by endothelins through decreasing the intracellular stability of mRNA molecules
37. Down-regulation of ET(B) receptor, but not ET(A) receptor, in congestive lung secondary to heart failure. Are marked increases in circulating endothelin-1 partly attributable to decreases in lung ET(B) receptor-mediated clearance of endothelin-1?
38. Reduced pulmonary clearance of endothelin-1 contributes to the increase of circulating levels in heart failure secondary to myocardial infarction
39. Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats
40. Coordinated upregulation of the cardiac endothelin system in a rat model of heart failure
41. Selective upregulation of cardiac endothelin system in patients with ischemic but not idiopathic dilated cardiomyopathy: Endothelin-1 system in the human failing heart
42. Pulmonary release and coronary and peripheral consumption of big endothelin and endothelin-1 in severe heart failure: Acute effects of vasodilator therapy
43. Conversion of big-endothelin-1 elicits an endothelin ETA receptor-mediated response in endothelial cells
44. Conversion of big ET-1 in the rat lung: Role of phosphoramidon-sensitive endothelin-1-converting enzyme
45. Direct enzyme immunometric measurement of plasma big endothelin-1 concentrations and correlation with indicators of left ventricular function