Down-regulation of ETB receptor, but not ETA receptor, in congestive lung secondary to heart failure. Are marked increases in circulating endothelin-1 partly attributable to decreases in lung ETB receptor-mediated clearance of endothelin-1?

Life Sciences

Volumn 62, Issue 2, 1997, Pages 185-193

  Kobayashi, Tsutomu ^a   Miyauchi, Takashi ^a   Sakai, Satoshi ^a   Maeda, Seiji ^a   Yamaguchi, Iwao ^a   Goto, Katsutoshi ^b   Sugishita, Yasuro ^a  

^a Dept Int Med Inst Clin M   (Japan)

^b Univ T   (Japan)

Author keywords

Congestive lung; Endothelin 1; ETA receptor; ETB receptor; Heart failure

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOBLOTTING; LUNG CONGESTION; NONHUMAN; RAT; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BLOOD; BLOOD PRESSURE; DISEASE MODEL; DOWN REGULATION; GENETICS; LUNG DISEASE; METABOLISM; ORGAN SIZE; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOTHELIN-1; HEART FAILURE, CONGESTIVE; LUNG DISEASES; ORGAN SIZE; POLYMERASE CHAIN REACTION; RATS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN;

EID: 0031599884     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)01064-3     Document Type: Article

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