Pulmonary release and coronary and peripheral consumption of big endothelin and endothelin-1 in severe heart failure: Acute effects of vasodilator therapy

Circulation

Volumn 102, Issue 10, 2000, Pages 1132-1138

  Stangl, Karl ^a   Dschietzig, Thomas ^a   Richter, Christoph ^a   Laule, Michael ^a   Stangl, Verena ^a   Tanis, Elsa ^a   Baumann, Gert ^a   Felix, Stephan B ^a,b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Endothelin; Heart failure; Hemodynamics; Lung

Indexed keywords

BIG ENDOTHELIN 1; ENDOTHELIN 1; NITROPRUSSIDE SODIUM; URAPIDIL;

ADULT; ARTICLE; CLINICAL ARTICLE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; FEMALE; HEART INDEX; HEMODYNAMICS; HUMAN; LUNG CAPILLARY PRESSURE; MALE; PRIORITY JOURNAL;

EID: 0034609575     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.102.10.1132     Document Type: Article

References (15)

1. Endothelin in human congestive heart failure
2. Human pulmonary circulation is an important site for both clearance and production of endothelin-1
3. Pulmonary big endothelin affects coronary tone and leads to enhanced, ET(A)-mediated coronary constriction in early endothelial dysfunction
4. Relationship between endothelin-1 extraction in the peripheral circulation anti systemic vascular resistance in patients with severe congestive heart failure
5. Release of endothelin from the porcine aorta: Inhibition by endothelium-derived nitric oxide
6. Hemodynamic effects of urapidil in arterial hypertension and congestive heart failure
7. A simple sequentially rejective multiple test procedure
8. Reduced pulmonary clearance of endothelin-1 in pulmonary hypertension
9. Downregulation of ET(B) receptor, but not ET(A) receptor in congestive lung secondary to heart failure: Are marked increases in circulating endothelin-1 partly attributable to decreases in lung ET(B) receptor-mediated clearance of endothelin-1?
10. Angiotensin-converting enzyme inhibition modulates endogenous endothelin in chronic canine thoracic inferior vena cava constriction
11. Hormones and hemodynamics in heart failure
12. Neither physical exercise nor alpha-1 and beta-adrenergic blockade affect plasma endothelin concentrations
13. Evidence for endothelin-l-mediated vasoconstriction in severe chronic heart failure: Endothelin antagonism in heart failure
14. Expression of endothelin-1, endothelin-converting enzyme, and endothelin receptors in chronic heart failure