Memory deficits and increased emotionality induced by β-amyloid (25-35) are correlated with the reduced acetylcholine release and altered phorbol dibutyrate binding in the hippocampus

Journal of Neurology

Volumn 248, Issue 9, 2001, Pages 1065-1079

  Olariu, A ^a   Tran, M H ^a   Yamada, K ^a   Mizuno, M ^a   Hefco, V ^b   Nabeshima, T ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b ALEXANDRU IOAN CUZA UNIVERSITY OF IASI   (Romania)

Author keywords

Cholinergic deficit; Emotional behavior; Memory impairment; Protein kinase C (PKC); amyloid

Indexed keywords

AMYLOID BETA PROTEIN; PHORBOL DIBUTYRATE; PROTEIN KINASE C; ACETYLCHOLINE; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); PEPTIDE FRAGMENT; TRITIUM;

ACETYLCHOLINE RELEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; AVOIDANCE BEHAVIOR; BINDING AFFINITY; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMOTIONALITY; ENZYME ACTIVATION; FRONTAL CORTEX; HIPPOCAMPUS; MALE; MAZE TEST; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; ALZHEIMER DISEASE; ANIMAL; BINDING COMPETITION; CELL MEMBRANE; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG EFFECT; EMOTIONAL DISORDER; ENZYMOLOGY; MEMORY DISORDER; METABOLISM; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION; WISTAR RAT;

ACETYLCHOLINE; AFFECTIVE SYMPTOMS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANXIETY; AVOIDANCE LEARNING; BINDING SITES; BINDING, COMPETITIVE; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMORY DISORDERS; MOTOR ACTIVITY; PEPTIDE FRAGMENTS; PROTEIN KINASE C; RATS; RATS, WISTAR; TRITIUM;

EID: 0035232594     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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