Luteinizing hormone-releasing hormone (LHRH) neurons: Mechanism of pulsatile LHRH release

Vitamins and Hormones

Volumn 63, Issue , 2001, Pages 91-129

  Terasawa, E I ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GONADORELIN;

ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; HUMAN; HYPOTHALAMUS; NERVE CELL; PHYSIOLOGY; PULSATILE FLOW; REVIEW; SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; GONADOTROPIN-RELEASING HORMONE; HUMANS; HYPOTHALAMUS; MODELS, BIOLOGICAL; NEURONS; PULSATILE FLOW; SIGNAL TRANSDUCTION;

EID: 0035231594     PISSN: 00836729     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0083-6729(01)63004-8     Document Type: Review

References (243)

1. R Abbud M.S Smith Do GnRH neurons express the gene for the NMDA receptor? Brain. Res. 690 1995 117 120
2. + currents underlying pacemaker potentials of fish gonadotropin-releasing hormone cells J. Neurophsiol. 81 1999 643 653
3. H Abe Y Oka Modulation of pacemaker activity by salmon gonadotropinreleasing hormone (sGnRH) in terminal nerve (TN)-GnRH neurons J. Neurophysiol. 83 2000 3196 3200
4. R Akema F Kimura Modulation of pulsatile LH secretion by baclofen, a selective GABAB receptor agonist, in ovariectomized rats Neuroendocrinology 56 1992 141 147
5. M Amoss R Burgus R Blackwell W Vale R Fellows R Guillemin Purification, amino acid composition and N-terminus of the hypothalamic luteinizing hormone releasing factor (LRF) of ovine origin Biochem. Biophys. Res. Commun. 44 1971 205 210
6. R.D Andrew F.E Dudek Burst discharge in mammalian neuroendocrine cells involves an intrinsic regenerative mechanism Science 221 1983 1050 1052
7. A Araque V Parpura R.P Sanzgiri P.G Haydon Tripartite synapses: glia, the unacknowledged partner Trends Neurosci. 22 1999 208 215
8. J.L Barker T.G Smith Bursting pacemaker activity in a peptidergic and peptide-sensitive neuron J.L Baker T.G Smith Jr. The Role of Peptides in Neuronal Function 1980 Dekker New York 189 228
9. C.A Barraclough E.M Wise M.K Selmanoff A role for hypothalamic catecholamines in the regulation of gonadotropin secretion Rec. Prog. Horm. Res. 40 1984 487 529
10. A, NMDA and AMPA receptors: A developmentally regulated ‘menage a trois’ Trends Neurosci. 20 1997 523 529
11. L.M Besecke J.E Levine Acute increase in responsiveness of luteinizing hormone (LH)-releasing hormone nerve terminals to neuropeptide-Y stimulation before the preovulatory LH surge Endocrinology 135 1994 63 66
12. L.M Besecke A.M Wolfe M.E Pierce J.S Takahashi J.E Levine Neuropeptide Y stimulates luteinizing hormone-releasing hormone release from superfused hypothalamic GT1-7 cells Endocrinology 135 1994 1621 1627
13. G.K Bhat V.B Mahesh C.A Lamar L Ping K Aguan D.W Brann Histochemical localization of nitric oxide neurons in the hypothalamus: Association with gonadotropin-releasing hormone neurons and co-localization with N-methyl-Daspartate receptors Neuroendocrinology 62 1995 187 197
14. A.N Bhattacharya D.J Dierschke T Yamaji E Knobil The pharmacologic blockade of the circhoral mode of LH secretion in ovariectomized rhesus monkeys Endocrinology 90 1972 778 786
15. S Boitano E.R Dirksen E.M Sanderson Intercellular propagation of calcium waves mediated by inositol triphosphate Science 258 1992 292 295
16. M.M Bosma Ion channel properties and episodic activity in isolated immortalized gonadotropin-releasing hormone (GnRH) neurons J. Membr. Biol. 136 1993 85 96
17. J.P Bourguignon A Gerard P Franchimont Direct activation of gonadotropin-releasing hormone secretion through different receptors to neuroexcitatory amino acids Neuroendocrinology 49 1989 402 408
18. J.P Bourguignon A Gerard M.L Alvarez Gonzalez L Fawes P Franchimont Gonadal-independent developmental changes in activation of N-methyl-Daspartate receptors involved in gonadotropin-releasing hormone secretion Neuroendocrinology 55 1992 634 641
19. A-receptor-mediated inhibition at initiation of sexual maturation J. Neuroendocrinol. 9 1997 193 199
20. D.W Brann V.B Mahesh Excitatory amino acids: Evidence for a role in the control of reproduction and anterior pituitary hormone secretion Endocr. Rev. 18 1997 678 700
21. D Brown A.E Herbison J.E Robinson R.W Marrs G Leng Modeling the luteinizing hormone-releasing hormone pulse generator Neuroscience 63 1994 869 879
22. 2+ and secretioy-vesicle dynamics Trends Neurosci. 18 1995 191 196
23. G.G Cadd K.K Clifton R.A Steiner Induction of galanin gene expression in GnRH and GHRH neurons: A common motif in pubertal maturation of the growth and reproductive axes T.M Plant P.A Lee The Neurobiology of Puberty 1995 Journal of Endocrinology Limited Bristol, UK 73 85
24. D Cao G Lin E.M Westphale E.C Beyer T.H Steinberg Mechanisms for the coordination of intercellular calcium signaling in insulin-secreting cells J. Cell Sci. 110 1997 497 504
25. H Cardenas T Ördög K.T O'Byrne E Knobil Single unit components of the hypothalamic multiunit electrical activity associated with the central signal generator that directs the pulsatile secretion of gonadotropic hormones Proc. Natl. Acad. Sci. USA 90 1993 9630 9634
26. P.W Carmel S Araki M Ferin Pituitary stalk portal blood collection in rhesus monkeys: Evidence of pulsatile release of gonadotropin-releasing hormone (GnRH) Endocrinology 99 1976 243 248
27. A.C Charles Intracellular calcium waves in glia Glia 24 1998 39 49
28. A.C Charles T.G Hales Mechanisms of spontaneous calcium oscillations and action potentials in immortalized hypothalamic (GT1-7) neurons J. Neurophysiol. 73 1995 56 64
29. A.C Charles S.K Kodali R.F Tyndale Intracellular calcium waves in neurons Mol. Cell Neurosci. 7 1996 337 353
30. G Chen A.N van den Pol Multiple NPY receptors coexist in pre- and postsynaptic sites: Inhibition of GABA release in isolated self-innervating SCN neurons J. Neurosci. 16 1996 7711 7724
31. E Cherubini J.L Gaiarsa Y Ben-Ari GABA: An excitatory transmitter in early postnatal life Trends Neurosci. 14 1991 515 519
32. I.J Clarke J.T Cummins The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in the ovariectomized ewe Endocrinology 111 1982 1737 1739
33. L.E Claypool E Kasuya Y Saitoh F Marzban E Terasawa N -methyl-dl-aspartate (NMA) induces the release of luteinizing hormone-releasing hormone (LHRH) in the prepubertal and pubertal female rhesus monkey as measured by in vivo push-pull perfusion in the stalk-median eminence Endocrinology 141 1999 219 228
34. P Cobbett G.I Hatton Dye coupling in hypothalamic slices: Dependence on in vivo hydration state and osmolality of incubation medium J. Neurosci. 4 1984 3034 3038
35. A.H Cornell-Bell S.N Finkbeiner M.S Cooper S.J Smith Glutamate induces calcium waves in cultured astrocytes: Long-lange glial signaling Science 247 1990 470 473
36. J.L Costantin A.C Charles Spontaneous action potentials initiate rhythmic intercellular calcium waves in immortalized hypothalamic (GT1-1) neurons J. Neurophysiol. 82 1999 429 435
37. M.L Cotrina H.-C Lin J.C Lépez-Garcia C.C.G Naus M Nedergaad ATP-mediated glial signaling J. Neurosci. 20 2000 2835 2844
38. W.R Crowley S.E Kalra Neuropeptide Y stimulates the release of luteinizing hormone-releasing hormone from medial basal hypothalamus in vitro : Modulation by ovarian hormones Neuroendocrinology 46 1987 97 103
39. D.W Dani A Chernjavsky S.J Smith Neuronal activity triggers calcium waves in hippocampal astrocyte networks Neuron 8 1992 429 440
40. L.V DePaolo L.A King A.J Carrillo in vivo and in vitro examination of an autoregulatory mechanism for luteinizing hormone-releasing hormone Endocrinology 120 1987 272 279
41. D.J Dierschke A.N Bhattacharya L.E Atkinson E Knobil Circhoral oscillations of plasma LH levels in the ovariectomized rhesus monkey Endocrinology 87 1970 850 853
42. A.O Donoso F.J Lopez A Negro-Vilar Glutamate receptors of the non-Nmethyl-D-aspartic acid type mediate the increase in luteinizing hormone-releasing hormone release by excitatory amino acids in vitro Endocrinology 126 1990 414 420
43. A.O Donoso F.J Lopez A Negro-Vilar Cross-talk between excitatory and inhibitory amino acids in the regulation of luteinizing hormone-releasing hormone secretion Endocrinology 131 1992 1559 1561
44. S.V Drouva J Epelbaum M Hery L.T Arancibia E Laplante C Kordon Ionic channels involved in the LHRH and SRIF release from rat mediobasal hypothalamus Neuroendocrinology 32 1981 155 162
45. A.H Duittoz M Batailler Pulsatile LHRH secretion from primary culture of sheep ( Ovis aries ) olfactory placode explants J. Reprod. Fertil. 120 2000 391 396
46. A.H Duittoz M Batailler M Caldani Primary cell culture of LHRH neurones from embryonic olfactory placode in the sheep ( Ovis aries ) J. Neuroendocrinol. 9 1997 669 675
47. M el-Etr Y Akwa R.J Fiddes P Robel E.E Baulieu A progesterone metabolite stimulates the release of gonadotropin-releasing hormone from GT1-1 hypothalamic neurons via the gamma-aminobutyric acid type A receptor Proc. Natl. Acad. Sci. USA 92 1995 2773 3769
48. M El Majdoubi A Sahu S Ramaswamy T.M Plant Neuropeptide Y: A hypothalamic brake restraining the onset of puberty in primates Proc. Natl. Acad. Sci. USA 97 2000 6179 6184
49. J.C Erickson K.E Clegg R.D Palmiter Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y Nature 381 1996 415 418
50. J.W Everett Neuroendocrine aspects of mammalian reproduction Ann. Rev. Physiol. 31 1969 383 416
51. O Eyigor L Jennes Changes in glutamate receptor subunit mRNAs in gonadotropin-releasing hormone neurons in rat brain Endocrine 4 1996 133 139
52. O Eyigor L Jennes Expression of glutamate receptor subunit mRNAs in gonadotropin-releasing hormone neurons during sexual maturation of the female rat Neuroendocrinology 66 1997 122 129
53. C Feleder H Jarry S Leonhardt W Wuttke J.A Moguilevsky The GABAergic control of gonadotropin-releasing hormone secretion in male rats during sexual maturation involves effects on hypothalamic excitatory and inhibitory amino acid systems Neuroendocrinology 64 1996 305 312
54. M Ferin D van Vugt S Wardlaw The hypothalamic control of the menstrual cycle and the role of endogenous opioid peptides Rec. Prog. Horm. Res. 40 1984 441 485
55. 2+ oscillations in cultured LHRH neurons derived from embryonic olfactory placode of the rhesus monkey Proc. 28th. Ann. Mtg. Soc. Neurosci. 24 1998 270 (No. 110.4)
56. S.A Ferreira C.J Scott D.E Kuehl G.L Jackson Differential regulation of luteinizing hormone release by γ-aminobutyric acid receptor subtypes in the arcuate-ventromedial region of the castrated ram Endocrinology 137 1996 3453 3460
57. P.R Findell K.H Wong J.K Jackman D.V Daniels Beta 1-adrenergic and dopamine (Dl)-receptors coupled to adenylyl cyclase activation in GTl gonadotropin-releasing hormone neurosecretory cells Endocrinology 132 1993 682 688
58. M Gambacciani J.H Liu W.H Swartz V.S Tueros S.C Yen D.O Rasmussen Intrinsic pulsatility of luteinizing hormone release from the human pituitary in vitro Neuroendocrinology 45 1987 402 406
59. V.L Gay T.M Plant N -Methyl-d,l-aspartate (NMDA) elicits hypothalamic gonadotropin-releasing hormone release in prepubertal male rhesus monkeys ( Macaca mulatta ) Endocrinology 120 1987 2289 2296
60. V.L Gay N.A Sheth Evidence for a periodic release of LH in castrated male and female rats Endocrinology 90 1972 158 162
61. M Gearing E Terasawa Luteinizing hormone-releasing hormone (LHRH) neuroterminals mapped using the push-pull perfusion method in the rhesus monkey Brain Res. Bull. 21 1988 117 121
62. 1-adrenergic neuronal system is involved in pulsatile release of luteinizing hormone-releasing hormone (LHRH) in the ovariectomized female monkey Neuroendocrinology 93 1991 373 381
63. M Gearing E Terasawa Suppression of luteinizing hormone (LH) release by the al-adrenergic receptor antagonist prazosin in the ovariectomized female rhesus monkey Am. J. Primatol. 25 1991 23 33
64. 2 mediates the stimulatory effect of methoxamine in in vivo luteinizing hormone-releasing hormone (LHRH) release in the ovariectomized female rhesus monkey Brain. Res. 560 1991 276 281
65. P.C Goldsmith K.K Thind Morphological basis for neuronal control of GnRH secretion in the monkey T.M Plant P.A Lee The Neurobiology of Puberty 1995 Journal of Endocrinology Ltd., Bristol, UK 73 85
66. P.C Goldsmith R Lamberts L.R Brezina Gonadotropin-releasing hormone neurons and pathways in the primate hypothalamus and forebrain R.L Norman Aspects of Reproduction 1983 Academic Press New York 7 45
67. J.D Gordon B.J Attardi D.W Pfaff Mathematical exploration of pulsatility in cultured gonadotropin-releasing hormone neurons Neuroendocrinology 67 1998 2 17
68. A.C Gore D Mitsushima E Terasawa A possible role of neuropeptide Y in the control of the onset of puberty in female rhesus monkeys Neuroendocrinology 58 1993 23 34
69. A.C Gore J.T Wu J.J Rosenberg J.L Roberts Gonadotropin-releasing hormone and NMDA receptor gene expression and colocalization change during puberty in female rats J. Neurosci. 16 1996 5281 5289
70. P.B Guthrie J Knappenberger M Segal M.V Bennett A.C Charles S.B Kater ATP released from astrocytes mediates glial calcium waves J. Neurosci. 19 1999 520 528
71. T.G Hales J.M Sanderson A.C Charles GABA has excitatory actions on GnRH-secreting immortalized hypothalamic (GTl-7) neurons Neuroendocrinology 59 1994 297 308
72. G.W Harris Neural Control of the Pituitary Gland 1955 Edward Arnold London
73. M.E Harris-White S.A Zanotti S.A Frautschy A.C Charles Spiral intercelluar calcium waves in hippocampal slice cultures J. Neurophysiol. 79 1998 1045 1052
74. T.D Hassinger P.B Guthrie P.B Atkinson M.V.L Bennett S.B Kaster An extracellular signaling component in propagation of astrocytic calcium waves Proc. Natl. Acad. Sci. USA 93 1996 13268 13273
75. G.I Hatton Reversible synapse formation and modulation of cellular relationships in the adult hypothalamus under physiological conditions C.W Cotman Synaptic Plasticity 1985 Guilford Press New York 373 404
76. G.L Hatton Q.Z Yang Incidence of neuronal coupling in supraoptic nuclei of virgin and lactating rats: Estimation by neurobiotin and lucifer yellow Brain Res. 650 1994 63 69
77. A.E Herbison Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons Endocr. Rev. 19 1998 302 330
78. A receptor regulation of mouse GnRH neurons over puberty J.-P Bourguignon T.M Plant The Onset of Puberty in Perspective 2000 Elsevier Amsterdam 145 155
79. H Hiruma F Kimura Luteinizing hormone-releasing hormone is a putative factor that causes LHRH neurons to fire synchronously in ovariectomized rats Neuroendocrinology 61 1995 509 516
80. H Hiruma T Uemura F Kimura Neuronal synchronization and ionic mechanisms for propagation of excitation in the functional network of immortalized GTl-7 neurons: Optical imaging with a voltage-sensitive dye J. Neuroendocrinol. 9 1997 835 840
81. A-receptors in the marmoset monkey: Expression of distinct subtypes in the pre- and postnatal brain J. Comp. Neurol. 367 1996 413 430
82. S Hosny L Jennes Identification of gap junctional connexin-32 mRNA and protein in gonadotropin-releasing hormone neurons of the female rats Neuroendocrinology 67 1998 101 108
83. S Hosny L Jennes Identification of alphalB adrenergic receptor protein in gonadotropin releasing hormone neurons of the female rat J. Neuroendocrinol. 10 1998 687 692
84. H Jarry S Leonhardt W Wuttke Gamma-aminobutyric acid neurons in the preopticlanterior hypothalamic area synchronized the phasic activity of the gonadotropin-releasing hormone pulse generator in ovariectomized rats Neuroendocrinology 51 1991 337 344
85. H Jarry A Perschl W Wuttke Further evidence that preoptic anterior hypothalamic GABAergic neurons are part of the GnRH pulse and surge generator Acta Endocr. 118 1988 573 579
86. L Jennes W.E Stumpf M.L Tappaz Anatomical relationships of dopaminergic and GABAergic systems with the GnRH-systems in the septo-hypothalamic area Exp. Brain Res. 50 1983 91 99
87. A receptor subunits are expressed in LHRH neurons in juvenile female rats Brain Res. 780 1998 218 229
88. S.P Kalra Neural circuitry involved in the control of LHRH secretion: A model for preovulatory LH release L Martini W.R Ganong Frontiers in Neuroendocrinology Vol. 9 1986 Raven Press New York 31 75
89. S.P Kalra Mandatory neuropeptide-steroid signal for the preovulatory luteinizing hormone-releasing hormone discharge Endocr Rev. 14 1993 507 538
90. P.S Kalra J.J Bonavera S.P Kalra Central administration of antisense oligodeoxynucleotide to neuropeptide Y (NPY) mRNA reveals the critical role of newly synthesized NPY in regulation of LHRH release Regul. Pept. 59 1995 215 220
91. E Kasuya M Mizuno G Watanabe E Terasawa Effects of an antisense oligodeoxynucleotide for neuropeptide-Y mRNA on in vivo LHRH release in ovariectomized female rhesus monkeys Regul. Pept. 75–76 1998 319 325
92. J.-M Kaufman J.S Kesner R.C Wilson E Knobil Electrophysiological manifestation of luteinizing hormone-releasing hormone pulse generator activity in the rhesus monkey: Influence of α-adrenergic blocking agents Endocrinology 116 1985 1327 1333
93. S Kawakami K Hirunagi M Ichikawa H Tsukamura K Maeda Evidence for terminal regulation of GnRH release by excitatory amino acids in the median eminence in female rats: A dual immunoelectron microscopic study Endocrinology 139 1998 1458 1461
94. M Kawakami T Uemura R Hayshi Electrophysiological correlates of pulsatile gonadotropin release in rats Neuroendocrinology 35 1982 63 67
95. A.H Kaynard K.-Y.F Pau D.L Hess H.G Spies Third-ventricular infusion of neuropeptide Y suppresses luteinizing hormone secretion in ovariectomized rhesus macaques Endocrinology 127 1990 2437 2444
96. A receptor blocker bicuculline on the onset of puberty in female rhesus monkeys Endocrinology 140 1999 5257 5266
97. J.S Kesner R.C Wilson J.-M Kaufman J Hotchkiss Y Chen H Yamamoto R.R Pardo E Knobil Unexpected responses of the hypothalamic gonadotropinreleasing hormone “pulse generator” to physiological estradiol inputs in the absence of the ovary Proc. Natl. Acad. Sci. USA 84 1987 8745 8749
98. O Khorram K.-Y.F Pau H Spies Bimodal effects of neuropeptide Y on hypothalamic release of gonadotropin-releasing hormone in conscious rabbits Neuroendocrinology 45 1987 290 297
99. F Kimura M Nishihara T Funabashi Naloxone increases the frequency of the electrical activity of luteinizing hormone-releasing hormone pulse generator in long-term ovariectomized rats J. Neuroendocrinol. 53 1991 97 105
100. J.C King B.S Rubin Dynamic changes in LHRH neurovascular terminals with various endocrine conditions in adults Horm. Behav. 28 1994 349 356
101. J.C King E.L.P Anthony D.M Fitzgerald E.G Stopa Luteinizing hormone-releasing hormone neurons in human preopticlhypothalamus: Differential interneuronal location of immunoreactive forms J. Clin. Endocrinol. Metab. 60 1985 88 97
102. E Knobil On the control of gonadotropin secretion in the rhesus monkey Rec. Prog. Horm. Res. 30 1974 1 46
103. E Knobil The neuroendocrine control of the menstrual cycle Rec. Prog. Horm. Res. 36 1980 53 88
104. H Kobayashi M Wada H Uemura The hypothalamic median eminence as a neuroendocrine organ Med. J. Osaka Univ. 23 1972 43 55
105. G.J Kokoris N.Y Lam M Ferin A.-J Silverman M.J Gibson Transplanted gonadotropin-releasing hormone neurons promote pulsatile luteinizing hormone secretion in congenitally hypogonadal (hyg) male mice Neuroendocrinology 48 1988 45 52
106. G.P Kozlowski P.W Coats Ependymoneuronal specializations between LHRH fibers and cells of the cerebroventricular system Cell Tissue Res. 242 1985 301 311
107. L.C Krey W.R Butler E Knobil Surgical disconnection of the medial basal hypothalamus and pituitary function in the rhesus monkey. I. Gonadotropin secretion Endocrinology 96 1975 1073 1087
108. L.Z Krsmanovic A.J Martinez-Fuetes K.K Arora N Mores C.E Navarro H.-C Chen S.S Stojilkovic K.J Catt Autocrine regulation of gonadotropinreleasing hormone secretion in cultured hypothalamic neurons Endocrinology 140 1999 1423 1431
109. L.Z Krsmanovic S.S Stojilkovic F Merelli S.M Dufour M.A Virmani K.J Catt Calcium signaling and episodic secretion of gonadotropin-releasing hormone in hypothalamic neurons Proc. Natl. Acad. Sci. USA 89 1992 8462 8466
110. L.Z Krsmanovic S.S Stojilkovic L.M Mertz G Tomic K.J Catt Expression of gonadotropin-releasing hormone receptors and autocrine regulation of neuropeptide release in immortalized hypothalamic neurons Proc. Natl. Acad. Sci. USA 90 1993 3908 3912
111. K Kusano S Fueshko H Gainer S Wray Electrical and synaptic properties of embryonic luteinizing hormone-releasing hormone neurons in explant cultures Proc Natl. Acad. Sci. USA 92 1995 3918 3922
112. A.H Lagrange O.K Ronnekleiv M.J Kelley Estradiol-17β and μ-opioid peptides rapidly hyperpolarized GnRH neurons: A cellular mechanism of negative feedback? Endocrinology 136 1995 2341 2344
113. R Lamberts E Vijayan M Graf T Mansky W Wuttke Involvement of preoptic-anterior hypothalamic GABA neurons in the regulation of pituitary LH and prolactin release Exp. Brain Res. 52 1983 356 362
114. G Leng D Brown The origins and significance of pulsatility in hormone secretion from the pituitary J. Neuroendocrinol. 9 1997 493 513
115. C Leranth N.J MacLusky T.J Brown E.C Chen D.E Redmond Jr. F Naftolin Transmitter content and afferent connections of estrogen-sensitive progestin receptor-containing neurons in the primate hypothalamus Neuroendocrinology 55 1992 667 682
116. J.E Levine P Chapel L.M Besecke A.C Bauer-Dantoin A.M Wolfe T Porkka-Heiskanen J.H Urban Amplitude and frequency modulation of pulsatile luteinizing hormone-releasing hormone release Cell Mol. Neurobiol. 15 1995 117 139
117. J.E Levine K.F Pan V.D Ramirez G.L Jackson Simultaneous measurement of luteinizing hormone-releasing hormone and luteinizing hormone release in unanesthetized ovariectomized sheep Endocrinology 111 1982 1449 1455
118. C Li P Chen M.S Smith Morphological evidence for direct interaction between arcuate nucleus neuropeptide Y (NPY) neurons and gonadotropin releasing hormone (GnRH) neurons and the possible involvement of NPY Yl receptors Endocrinology 140 1999 5382 5390
119. D.W Lincoln J.B Wakerley Electrophysiological evidence for the activation of supraoptic neurons during the release of oxytocin J. Physiology. 242 1974 533 554
120. Z Liposits I Merchenthaler W.C Wetsel J.J Reid P.L Mellon R.I Weiner A Negro-Vilar Morphological characterization ofimmortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone Endocrinology 129 1991 1575 1583
121. F.L Lopez A Negro-Vilar Galanin stimulates luteinizing hormonereleasing hormone secretion from arcuate nucleus-median eminence fragments in vitro : Involvement of an α-adrenergic mechanism Endocrinology 127 1990 2431 2436
122. P Mahachoklertwuttana J Sanchez S.L Kaplan M.M Grumbach N -methyl-d-aspartate (NMDA) receptors mediate the release of gonadotropin-releasing hormone (GnRH) by NMDA in a hypothalamic GnRH neuronal cell line (GT 1-1) Endocrinology 134 1994 1023 1030
123. S.K Mann J.M Brown C Briscoe C Parent G Pitt P.N Devreotes R.A Firtel Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium Dev. Biol. 183 1997 208 221
124. E Marder S.L Hooper Neurotransmitter modulation of the stomatogastric ganglion of decapod crustaceans A.I Selverston Model Neural Networks and Behavior 1989 Plenum New York 319 337
125. G Martinez de la Escalera A.L Choi R.I Weiner Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: Intrinsic properties of the GTl-1 GnRH neuronal cell line Proc. Natl. Acad. Sci. USA 89 1992 1852 1855
126. G Martinez de la Escalera A.L Choi R.I Weiner Beta 1-adrenergic regulation of the GTl gonadotropin-releasing hormone (GnRH) neuronal cell lines: Stimulation of GnRH release via receptors positively coupled to adenylate cyclase Endocrinology 131 1992 1397 1402
127. G Martinez de la Escalera A.L Choi R.I Weiner Biphasic gabaergic regulation of GnRH secretion in GTl cell lines Neuroendocrinology 59 1994 420 425
128. G Martinez de la Escalera F Gallo A.L Choi R.I Weiner Dopaminergic regulation of the GTl gonadotropin-releasing hormone (GnRH) neuronal cell lines: Stimulation of GnRH release via Dl-receptors positively coupled to adenylate cyclase Endocrinology 131 1992 2965 2971
129. C Massoto A Negro-Vilar Activation of γ-aminobutyric acid B-receptors abolishes naloxone-stimulated luteinizing hormone release Endocrinology 121 1987 2251 2255
130. M.F Matesic J.A Germak E Dupont B.V Vadhuker Immortalized hypothalamic luteinizing hormone-releasing hormone neurons express a connexin 26-like protein and display functional gap junction coupling assayed by fluorescence recovery after photobleaching Neuroendocrinology 58 1993 485 492
131. D.F Matesic T Hayashi J.E Trosko J.A Germak Upregulation of gap junctional intercellular communication in immortalized gonadotropin-releasing hormone neurons by stimulation of the cyclic AMP pathway Neuroendocrinology 64 1996 286 297
132. H Matsuo A Arimura R.M Nair A.V Schally Synthesis of the porcine LH- and FSH-releasing hormone by the solid-phase method Biochem. Biophys. Res. Commun. 45 1971 822 827
133. J.K McDonald J Tigges M Tigges C Reich Developmental study of neuropeptide Y-like immunoreactivity in the neurohypophysis and intermediate lobe of the rhesus monkey ( Macaca mulatta ) Cell Tissue Res. 254 1988 499 509
134. T.M McShane T May J.L Miner D.H Keisler Central action of neuropeptide-Y may provide a neuromodulatory link between nutrition and reproduction Biol. Reprod. 46 1992 1151 1157
135. P.L Mellon J.J Windle P.C Goldsmith C.A Padula J.L Roberts R.I Weiner Immortalization of hypothalamic GnRH neurons by genetically targeted tumorgenesis Neuron 5 1990 1 10
136. D Mitsushima D.L Hei E Terasawa γ-aminobutyric acid is an inhibitory neurotransmitter restricting the release of luteinizing hormone-releasing hormone before the onset of puberty Proc. Natl. Acad. Sci. USA 91 1994 395 399
137. D Mitsushima F Marzban L.L Luchansky A.J Burich K.L Keen M Durning T.G Golos E Terasawa Role of glutamic acid decarboxylase in the prepubertal inhibition of the luteinizing hormone-releasing hormone release in prepubertal female monkeys J. Neurosci. 16 1996 2563 2573
138. S.M Moenter R.M Brand A.R Midgely F.J Karsch Dynamics of GnRH secretion during a pulse Endocrinology 130 1992 503 510
139. J.A Moguilevsky S Carbone B Szwarcfarb D Rondina Sexual maturation modifies the GABAergic control of gonadotrophin secretion in female rats Brain Res. 563 1991 12 16
140. Y Mori M Nishihara T Tanaka T Shimizu M Yamaguchi Y Takeuchi K Hoshino Chronic recording of electrophysiological manifestation of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator activity in the goat Neuroendocrinology 53 1991 392 395
141. Y Mori T Tanaka T Hamada Y Takeuchi External and internal regulating GnRH secretion in ruminant species K Maeda H Tsukamura A Yokoyama Neural Control of Reproduction: Physiology and Behavior 1997 Karger Basel 103 120
142. 2+ waves are organized among hepatocytes in the intact organ Am. J. Physiol. 269 1995 G167 G171
143. M Nedergaard Direct signaling from astrocytes to neurons in cultures of mammalian brain cells Science 263 1994 1768 1771
144. E.A Newman K.A Zahs Calcium waves in retinal glial cells Science 257 1997 844 847
145. K.E Nikolarakis J.P Loeflier O.F.X Almeida A Herz Pre- and postsynaptic actions of GABA on the release of hypothalamic gonadotropin-releasing hormone (GnRH) Brain Res. Bull. 21 1988 677 683
146. M Nishihara H Hiruma F Kimura Interaction between the noradrenergic and opioid peptidergic systems in controlling the electrical activity of luteinizing hormone-releasing hormone pulse generator in ovariectomized rats Neuroendocrinology 54 1991 321 326
147. R.B Norgren M.N Lehman A double-label pre-embedding immunoperoxidase technique for electron microscopy using diaminobenzidine and teramethylbenzidine as markers J. Histochem. Cytochem. 37 1989 1283 1289
148. L Nunez C Villalobos F.R Boockfor L.S Frawley The relationship between pulsatile secretion and calcium dynamics in single, living GnRH neurons Endocrinology 141 2000 2012 2017
149. K Obrietan A.N van den Pol Neuropeptide Y depresses GABA-mediated calcium transients in developing suprachiasmatic nucleus neurons: A novel form of calcium long-term depression J. Neurosci. 16 1996 3521 3533
150. 2+ Endocrinology 104 1979 617 624
151. 2 and luteinizing hormone-releasing hormone release from the median eminence Endocrinology 110 1982 409 412
152. Y Oka Gonadotropin-releasing hormone (GnRH) cells of the terminal nerve as a model neuromodulator system Neurosci. Lett. 140 1992 1 4
153. + current underlying pacemaker potential of fish gonadotropin-releasing hormone neurons J. Physiol. (London) 482 1995 1 6
154. + current underlying pacemaker potentials of fish gonadotropin-releasing hormone (GnRH) neurons J. Neurosci. 75 1996 2397 2404
155. Y Oka T Matsushima Gonadotropin-releasing hormone (GnRH)immunoreactive terminal nerve cells have intrinsic rhythmicity and project widely in the brain J. Neurosci. 13 1993 2161 2176
156. J.G Ondo Gamma-aminobutyric acid effects on pituitary gonadotropin secretion Science 186 1974 738 739
157. T Ördög M.D Chen M Nishihara M.A Connaughton J.R Goldsmith E Knobil On the role of gonadotropin-releasing hormone (GnRH) in the operation of the GnRH pulse generator in the rhesus monkey Neuroendocrinology 65 1997 307 713
158. Y Osipchuk M Cahalan Cell-to cell spread of calcium signals mediated by ATP receptors in mast cells Nature 359 1992 241 244
159. V Parpura T.A Basarsky F Liu K Jeftinija S Jeftinija P.G Haydon Glutamate-mediated astrocyte-neuron signaling Nature 369 1994 744 747
160. K.-Y.F Pau A.M Berria D.L Hessm H.G Spies Hypothalamic sitedependent effects of neuropeptide Y on gonadotropin-releasing hormone secretion in rhesus macaques J. Neuroendocrinol. 7 1995 63 67
161. o regulation Am. J. Physiol. 273 1997 C1516 C1525
162. A receptor subunit mRNAs in cells of the preoptic area: Colocalization with LHRH mRNA using dual-label in situ hybridization histochemistry Endocr J. 1 1993 29 34
163. T.M Plant V.L Gay G.R Marshall M Arslan Puberty in monkeys is triggered by chemical stimulation of the hypothalamus Proc. Natl. Acad. Sci. USA 86 1989 2506 2510
164. T.M Plant Y Nakai P Belchetz E Keogh E Knobil The sites of action of estradiol and phentolamine in the inhibition of the pulsatile, circhoral discharges of LH in the rhesus monkey ( Macaca mulatta ) Endocrinology 102 1978 1015 1018
165. D.A Poulain J.B Wakerley Electrophysiology of hypothalamic magnocellular neurons secreting oxytocin and vasopressin Neuroscience 7 1982 773 808
166. M.O Poulter L Ohannesian Y Larmet P Feltz Evidence that GABAA receptor subunit mRNA expression during development is regulated by GABAA receptor stimulation J. Neurochem. 68 1997 631 639
167. M.T Price J.W Olney T.J Cicero Acute elevations of serum luteinizing hormone induced by kainic acid, N -methyl-aspartic acid, or homosysteic acid Neuroendocrinology 26 1978 352 358
168. S Pu E Terasawa Effects of neurotensin and atrial natriuretic peptide on the in vivo release of luteinizing hormone-releasing hormone in the stalk-median eminence in ovariectomized female rhesus monkeys Proc. 22nd Ann. Mtg. Soc. Neurosci. 19 1993 619 (No. 258.11)
169. S Pu E Terasawa Effects of an LHRH agonist analog infusion on the pulsatile release of LHRH and NPY Proceedings of the 76th Annual Meeting of the Endocrine Society 1994 521 (No. 1281)
170. 2+ entry J. Neurosci. 17 1997 8169 8177
171. C Quanbeck N.M Sherwood R.P Millar E Terasawa Two populations of luteinizing hormone-releasing hormone neurons in the forebrain of the rhesus macaque during embryonic development J. Comp. Neurol. 380 1997 293 309
172. S Radovick S Wray E Lee D.K Nicols Y Nakayama B.D Weintraub H Wetphal G.B Cutler Jr. F.E Wondisford Migratory arrest of gonadotropinreleasing hormone neurons in transgenic mice Proc. Natl. Acad. Sci. USA 88 1991 3402 3406
173. S Radovick C.M Ticknor Y Nakayama A.C Notides A Rahman Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene J. Clin. Invest. 88 1991 1649 1655
174. V.D Ramirez H.H Feder C.H Sawyer The role of brain catecholamines in the regulation of LH secretion: A critical inquiry Front. Neuroendocrinol. 7 1984 27 84
175. V.D Ramirez E Gallardo D Hatter Factors altering the secretion of LHRH from superfused fragments of rat hypothalamus J. Endocrinol. Invest. 3 1980 29 37
176. V Rettori N Belova W.L Dees C.L Nyberg M Gimeno S.M McCann Role of nitric oxide in the control of luteinizing hormone-releasing hormone release in vivo and in vitro Proc. Natl. Acad. Sci., USA 90 1993 10130 10134
177. S.B Richardson J.A Prasad C.S Hollander Acetylcholine, melatonin, and potassium depolarization stimulate release of luteinizing hormone-releasing hormone from rat hypothalamus in vitro Proc. Natl. Acad. Sci. USA 79 1982 2686 2689
178. − co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation Nature 397 1999 251 255
179. O.K Ronnekleiv J.A Resko Ontogeny of gonadotropin-releasing hormone-containing neurons in early fetal development of rhesus macaques Endocrinology 126 1990 498 511
180. H Sakakibara M Conti R.I Weiner Role of phosphodiesterases in the regulation of gonadotropin-releasing hormone secretion in GT1 cells Neuroendocrinology 68 1998 365 373
181. 2+ in epithelial cells Cell. Regul. 1 1990 585 596
182. C.H Sawyer Some recent developments in brain-pituitary-ovarian physiology Neuroendocrinology 17 1975 97 124
183. A.U Schally A Arimura A.J Kastin H Matsuo Y Baba T.W Redding R.M Nair L Debeljuk W.F White Gonadotropin-releasing hormone: One polypeptide regulates secretion of luteinizing and follicle-stimulating hormones Science 173 1971 1036 1038
184. E.M Schuman D.V Madison Nitric oxide and synaptic function Ann. Rev. Neurosci. 17 1994 153 183
185. M Schwanzel-Fukuda D.W Pfaf Origin of luteinizing hormone-releasing hormone neurons Nature 338 1989 161 163
186. M Selmanoff Commentary on the use of immortalized neuroendocrine cell lines for physiological research Endocrine 6 1997 1 3
187. A.J Silverman The gonadotropin-releasing hormone (GnRH) neuronal systems: Immunocytochemistry E Knobil J.D Neill The Physiology of Reproduction 1988 Raven Press New York 1283 1304
188. A.J Silverman J.L Antunes G.M Abrams G Nilaver R Thau J.A Robinson M Ferin L.C Krey The luteinizing hormone-releasing hormone pathways in rhesus ( Macaca mullata ) and pigtailed ( Macaca nemestrina ) monkeys: New observations on thick, unembedded sections J. Comp. Neurol. 211 1982 309 317
189. A.J Silverman J.L Roberts K.W Dong G.M Miller M.J Gibson Intrahypothalamic injection of a cell line secreting gonadotropin-releasing hormone results in cellular differentiation and reversal of hypogonadism in mutant mice Proc. Natl. Acad. Sci. USA 89 1992 10668 10672
190. A.J Silverman R Wilson J.S Kesner E Knobil Hypothalamic localization of multiunit electrical activity associated with pulsatile LH release in the rhesus monkey Neuroendocrinology 44 1993 168 171
191. J.A Sim M.J Skynner J.-R Pape A.E Herbison Late postnatal reorganization of GABAA receptor signaling in native GnRH neurons Eur. J. Neurosci. 12 2000 3497 3504
192. M Skynner J.A Sim R.G Dyer N Allen A.E Herbison Promoter transgenics reveal multiple gonadotropin-releasing hormone-expressing cell populations of different embryological origin in mouse brain J. Neurosci. 19 1999 5955 5966
193. A receptor α4 subunit suppression prevents withdrawal properties of an endogenous steroid Nature 392 1998 926 929
194. S.H Snyder D.S Bredt Nitric oxide as a neuronal messenger Trends Pharmacol. Sci. 12 1991 125 128
195. M.A Sortino G Aleppo U Scapagnini P.L Canonico Involvement of nitric oxide in the regulation of gonadotropin-releasing hormone release from the GT1-1 neuronal cell line Endocrinology 134 1994 1782 1787
196. i and neuropeptide secretion in immortalized gonadotropin-releasing hormone neurons Neuroendocrinology 61 1995 499 508
197. D.J Spergel D.F Krüth R Hanley R Sprengel P.H Seeburg GABA and glutamate-activated channels in green fluorescent protein tagged gonadotropin releasing hormone neurons in transgenic mice J. Neurosci. 19 1999 2037 2050
198. R.A Steiner W.J Bremner D.K Clifton Regulation of luteinizing hormone pulse frequency and amplitude by testosterone in the adult male rat Endocrinology 111 1982 2055 2061
199. K.J Suter W.J Song T.L Sampson J.-P Wuarin J.T Saunders F.D Dudek S.M Moenter Genetic targeting of green fluorescent protein to gonadotropin-releasing hormone neurons: Characterization of whole-cell electrophysiological properties and morphology Endocrinology 141 2000 412 419
200. K.J Suter J.-P Wuarin B.N Smith F.D Dudek S.M Moenter Whole cell recording from hypothalamic slices reveal burst firing in gonadotropin-releasing hormone (GnRH) neurons identified with green fluorescent protein (GFP) in transgenic mice Endocrinology 141 2000 3731 3736
201. E Terasawa Control of luteinizing hormone-releasing hormone pulse generation in nonhuman primates Cell. Mol. Neurobiol. 15 1995 141 164
202. 1 signaling and LHRH neurosecretion from LHRH neurons in rhesus monkeys Proceedings of the 82nd Annual Meeting of the Endocrine Society 2000 132 (No. 524)
203. E Terasawa K.L Keen K Mogi P Claude Pulsatile release of luteinizing hormone-releasing hormone in cultured LHRH neurons derived from the embryonic olfactory placode of the rhesus monkey Endocrinology 140 1999 1432 1441
204. E Terasawa C Krook D.L Hei M Gearing N.J Schultz G.A Davis Norepinephrine is a possible neurotransmitter stimulating pulsatile release of luteinizing hormone releasing hormone in the rhesus monkey Endocrinology 123 1988 1808 1816
205. E Terasawa L.L Luchansky E Kasuya C.L Nyberg An increase in glutamate release follows a decrease in gamma aminobutyric acid (GABA) and the pubertal increase in LHRH release in female rhesus monkeys J. Neuroendocrinol. 11 1999 275 282
206. in vitro studies K Maeda H Tsukamura A Yokoyama Neural Control of Reproduction: Physiology and Behavior 1997 Karger Basel 57 70
207. E Terasawa C.D Quanbeck C.A Schulz A.J Burich L.L Luchansky P Claude A primary cell culture system of luteinizing hormone releasing hormone (LHRH) neurons derived from fetal olfactory placode in the rhesus monkey Endocrinology 133 1993 2379 2390
208. 2+ oscillations in luteinizing hormone-releasing hormone (LHRH) cells derived from the embryonic olfactory placode of the rhesus monkey J. Neurosci. 19 1999 5898 5909
209. J.-C Thalabard M.-L Goubillon A.-C Camproux G Thomas Stochiastic modeling of rhythmic neuronal patterns: Application to the hypothalamic pulse generator K Maeda H Tsukamura A Yokoyama Neural Control of Reproduction: Physiology and Behavior 1994 Karger Basel 17 30
210. P.-S Tsai R.I Weiner Cell biology of GT1 GnRH neurons I.S Parhar Y Sakuma GnRH Neurons: Gene to Behavior 1997 Brain Shuppan Tokyo 439 457
211. Y Tsuruo H Kawano Y Kagotani S Hirano S Daikoku K Chihara T Zhang N Yanaihara Morphological evidence for neuronal regulation of luteinizing hormone-releasing hormone-containing neurons by neuropeptide Y in the rat septo-preoptic area Neurosci. Lett. 110 1990 261 266
212. F.W Turek J Swann D Earnest Role of the circadian system in reproductive phenomena Rec. Prog. Horm. Res. 40 1984 143 177
213. H Uemura J Nishimura H Yamaguchi H Hiruma F Kimura H Minaguchi Effects of noradrenaline on GnRH-secreting immortalized hypothalamic (GT1-7) neurons Endocr. J. 44 1997 73 78
214. J.H Urban I Das J.E Levine Steroid modulation of neuropeptide Y induced luteinizing hormone releasing hormone release from median eminence fragments from male rats Neuroendocrinology 63 1996 112 119
215. H.F Urbanski S.R Ojeda Activation of luteinizing hormone-releasing hormone release advances the onset of female puberty Neuroendocrinology 46 1987 273 276
216. H.F Urbanski S.R Ojeda A role for N -methyl-d-aspartate (NMDA) receptors in the control of LH secretion and initiation of female puberty Endocrinology 126 1990 1774 1776
217. A.N van den Pol Dual ultrastructural localization of two neurotransmitter-related antigens: Colloidal gold-labeled neurophysin immunoreactive supraoptic neurons receive peroxidase-labeled glutamate decarboxylase or gold-labeled GABA immunoreactive synapses J. Neurosci. 5 1985 2940 2954
218. A.N van den Pol K Obrietan G Chen A.B Belousov Neuropeptide Y mediated long-term depression of excitatory activity in suprachiasmatic nucleus neurons J. Neurosci. 16 1996 5883 5895
219. A.N van den Pol P.Q Trombley Glutamate neurons in hypothalamus regulate excitatory transmission J. Neurosci. 13 1993 2829 2836
220. F Van Goor L.Z Krsmnovic K.J Catt S.S Stojikovic Control of action potential-driven calcium influx in GTl neurons by activation status of sodium and calcium channels Mol. Endocrinol. 13 1999 587 603
221. F Van Goor L.Z Krsmnovic K.J Catt S.S Stojikovic Coordinated regulation of gonadotropin-releasing hormone neuronal firing patterns by cytosolic calcium and store depletion Proc. Natl. Acad. Sci. USA 96 1999 4101 4106
222. F Van Goor L.Z Krsmnovic K.J Catt S.S Stojikovic Autocrine regulation of calcium influx and gonadotropin-releasing hormone secretion in hypothalamic neurons Biochem. Cell Biol. 78 2000 359 370
223. E Vijayan S.M McCann The effects of intraventricular injection of Y-aminobutyric acid (GABA) on prolactin and gonadotropin release in conscious female rats Brain Res. 155 1978 35 43
224. F.A Vitalis J.L Costantin P.-S Tsai H Sakakibara S Paruthiyil T Iiri J.-F Martini M Taga A.L.H Choi A.C Charles R.I Weiner Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GTl cells Proc. Natl. Acad. Sci. USA 97 2000 1861 1866
225. M von Krosigk T Bal D.A McCormick Cellular mechanisms of a synchronized oscillation in the thalamus Science 261 1993 361 364
226. S Wagner M Castel H Gainer Y Yarom GABA in the mammalian suprachiasmatic nucleus and its role in diurnal rhythmicity Nature 387 1997 598 603
227. H Wang H.C Christian J.F Morris Dissociation of nitric oxide synthase immunoreactivity and NADPH-diaphorase enzyme activity in rat pituitary J. Endocrinol. 154 1997 R7 R11
228. W.C Wetsel M.M Valenca I Merchenthaler Z Lipositz F.J Lopez R.I Weiner P.L Mellon A Negro-Vilar Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone secreting neurons Proc. Natl. Acad. Sci. USA 89 1992 4149 4153
229. R.C Wilson J.S Kesner J.M Kaufman T Uemura T Akema E Knobil Central electrophysiologic correlates of pulsatile luteinizing hormone secretion in the rhesus monkey Neuroendocrinology 39 1984 256 260
230. J.W Witkin Aging changes in synaptology of luteinizing hormone-releasing hormone neurons in male rat preoptic area Neuroscience 22 1987 1003 1013
231. J.W Witkin Synchronized neuronal networks: The GnRH system Microsc. Res. Tech. 44 1999 11 18
232. J.W Witkin M Ferin S.J Popilskis A.J Silverman Effects of gonadal steroids on the ultrastructure of GnRH neurons in the rhesus monkey: Synaptic input and filial apposition Endocrinology 129 1991 1083 1092
233. J.W Witkin M.T Romero Comparison of ultrastructural characteristics of gonadotropin-releasing hormone neurons in prepubertal and adult male rats Neuroscience 64 1995 1145 1151
234. M.J Woller E Terasawa Infusion of neuropeptide Y into the stalk-median eminence stimulates in vivo release of luteinizing hormone-releasing hormone in gonadectomized rhesus monkeys Endocrinology 128 1991 1144 1150
235. M.J Woller E Terasawa Estradiol enhances the action of neuropeptide Y on in vivo luteinizing hormone-releasing hormone release in the ovariectomized rhesus monkey Neuroendocrinology 56 1992 921 925
236. M.J Woller J.K McDonald D.M Reboussin E Terasawa Neuropeptide Y is a neuromodulator of pulsatile LHRH release in the gonadectomized rhesus monkey Endocrinology 430 1992 2333 2342
237. S Wray P Grant H Gainer Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode Proc. Natl. Acad. Sci. USA 86 1989 8132 8136
238. S Wray S Key R Qualls S.M Fueshko A subset of peripherin positive olfactory axons delineates the luteinizing hormone releasing hormone neuronal migratory pathway in developing mouse Dev. Biol. 166 1994 349 354
239. A Yamane E Terasawa Pulsatile LHRH release is independently controlled by the alpha-adrenergic and neuropeptide Y neuronal systems in the rhesus monkey Proc. 22nd Ann. Mtg. Soc. Neurosci. 18 1992 192
240. Q.Z Yang G.I Hatton Direct evidence for electrical coupling among rat supraoptic nucleus neurons Brain Res. 463 1988 47 56
241. B Xu S Pu P.S Kalra J.F Hyde W.R Crowley S.P Kalra An interactive physiological role of neuropeptide Y and galanin in pulsatile pituitary luteinizing hormone secretion Endocrinology 137 1996 5297 5302
242. S Zhen I.C Dunn S Wray Y Liu P.E Chappell J.E Levine S Radovick An alternative gonadotropin-releasing hormone (GnRH) RNA splicing product found in cultured GnRH neurons and mouse hypothalamus J. Biol. Chem. 272 1997 12620 12625
243. L Zheng L.Z Krsmanovic L.A Vergara K.J Catt S.S Stojilkovic Dependence of intracellular signaling and neurosecretion on phospholipase D activation in immortalized gonadotropin-releasing hormone neurons Proc. Natl. Acad. Sci. USA 94 1997 1573 1578