Effects of an antisense oligodeoxynucleotide for neuropeptide Y mRNA on in vivo luteinizing hormone-releasing hormone release in ovariectomized female rhesus monkeys

Regulatory Peptides

Volumn 75-76, Issue , 1998, Pages 319-325

  Kasuya, Etsuko ^a   Mizuno, Masaharu ^a   Watanabe, Gen ^c   Terasawa, Ei ^a,b  

^a UNIVERSITY OF WISCONSIN   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

Antisense oligodeoxynucleotides; Luteinizing hormone releasing hormone (LHRH); Neuropeptide Y (NPY); Rhesus monkey

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; MESSENGER RNA; NEUROPEPTIDE Y;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GONADORELIN RELEASE; INTRACEREBRAL DRUG ADMINISTRATION; MONKEY; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ANIMALS; BASE SEQUENCE; FEMALE; GONADOTROPIN-RELEASING HORMONE; HUMANS; MACACA MULATTA; MEDIAN EMINENCE; NEUROPEPTIDE Y; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OVARIECTOMY; RNA, MESSENGER;

MACACA MULATTA;

EID: 0032566804     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(98)00084-6     Document Type: Article

References (35)

1. Kalra S.P., Crowley W.R. Norepinephrine-like effects of neuropeptide Y on LH release in the rat. Life Sci. 35:1984;1173-1176.
2. McDonald J.K., Lumpkin M.D., Samson W.K., McCann S.M. Neuropeptide Y affects secretion of luteinizing hormone and growth hormone in ovariectomized rats. Proc Natl Acad Sci USA. 82:1985;561-564.
3. Allen L.G., Kalra P.S., Crowley W.R., Kalra S.P. Comparison of the effects of neuropeptide Y and adrenergic transmitters on LH release and food intake in male rats. Life Sci. 37:1985;616-623.
4. Khorram O., Pau K.-Y.F., Spies H.G. Bimodal effects of neuropeptide Y on hypothalamic release of gonadotropin-releasing hormone in conscious rabbits. Neuroendocrinology. 45:1987;290-297.
5. Crowley W.R., Kalra S.P. Neuropeptide Y stimulates the release of luteinizing hormone-releasing hormone from medial basal hypothalamus in vitro: modulation by ovarian hormones. Neuroendocrinology. 46:1987;97-103.
6. McDonald J.K. Role of neuropeptide Y in reproductive function. Ann NY Acad Sci. 611:1990;258-272.
7. Bauer-Dantoin A.C., McDonald J.K., Levine J.E. Neuropeptide Y potentiates luteinizing hormone (LH)-releasing hormone-stimulated LH surges in pentobarbital-blocked proestrous rats. Endocrinology. 129:1991;402-408.
8. Woller M.J., McDonald J.K., Reboussin D.M., Terasawa E. Neuropeptide Y is a neuromodulator of pulsatile luteinizing hormone-releasing hormone release in the gonadectomized rhesus monkey. Endocrinology. 130:1992;2333-2342.
9. Woller M.J., Terasawa E. Infusion of neuropeptide Y into the stalk-median eminence stimulates in vivo release of luteinizing hormone-releasing hormone in gonadectomized rhesus monkeys. Endocrinology. 128:1991;1144-1150.
10. Woller M.J., Terasawa E. Estradiol enhances the action of neuropeptide Y on in vivo luteinizing hormone-releasing hormone release in the ovariectomized rhesus monkey. Neuroendocrinology. 56:1992;921-925.
11. Woller M.J., Terasawa E. Changes in pulsatile release of neuropeptide-Y and luteinizing hormone (LH)-releasing hormone during the progesterone-induced LH surge in rhesus monkeys. Endocrinology. 135:1994;1679-1686.
12. Terasawa E., Krook C., Hei D.L., Gearing M., Schultz N.J., Davis G.A. Norepinephrine is a possible neurotransmitter stimulating pulsatile release of luteinizing hormone-releasing hormone in the rhesus monkey. Endocrinology. 123:1988;1808-1816.
13. Gearing M., Terasawa E. The alpha-1-adrenergic neuronal system is involved in the pulsatile release of luteinizing hormone-releasing hormone in the ovariectomized female rhesus monkey. Neuroendocrinology. 53:1991;373-381.
14. Cohen J.S. Oligonucleotides as therapeutic agents. Pharmacol Ther. 52:1991;211-225.
15. Landgraf R. Antisense targeting in behavioural neuroendocrinology. J Neuroendocrinol. 151:1996;333-340.
16. Gearing M., Terasawa E. Luteinizing hormone-releasing hormone (LHRH) neuroterminals mapped using the push-pull perfusion method in the rhesus monkey. Brain Res Bull. 21:1988;117-121.
17. Watanabe G., Terasawa E. In vivo release of luteinizing hormone-releasing hormone increases with puberty in the female rhesus monkey. Endocrinology. 125:1989;92-99.
18. Merriam G.R., Wachter K.W. Algorithms for the study of episodic hormone secretion. Am J Physiol. 243:1982;E310-E318.
19. Xu B., Pu S., Kalra P.S., Hyde J.F., Crowley W.R., Kalra S.P. An interactive physiological role of neuropeptide Y and galanin in pulsatile pituitary luteinizing hormone secretion. Endocrinology. 137:1996;5297-5302.
20. Kalra P.S., Bonavera J.J., Kalra S.P. Central administration of antisense oligodeoxynucleotide to neuropeptide Y (NPY) mRNA reveals the critical role of newly synthesized NPY in regulation of LHRH release. Regul Pept. 59:1995;215-220.
21. Hulsey M.G., Pless C.M., White B.D., Martin R.J. ICV administration of anti-NPY antisense oligonucleotide: effects on feeding behavior, body weight, peptide content and peptide release. Regul Pept. 59:1995;207-214.
22. Mitsushima D., Marzban F., Luchansky L.L., Burich A.J., Keen K.L., Durning M., Golos T.G., Terasawa E. Role of glutamic acid decarboxylase in the prepubertal inhibition of the luteinizing hormone-releasing hormone release in female rhesus monkeys. J Neurosci. 16:1996;2563-2573.
23. Silverman AJ. The gonadotropin-releasing hormone (GnRH) neuronal systems: immunocytochemistry. In: Knobil E, Neill J, editors. The Physiology of Reproduction. New York: Raven Press, 1988:1283-1304.
24. McDonald J.K., Tigges J., Tigges M., Reich C. Developmental study of neuropeptide Y-like immunoreactivity in the neurohypophysis and intermediate lobe of the rhesus monkey (Macaca mulatta). Cell Tissue Res. 254:1988;499-509.
25. Yamane A., Terasawa E. Pulsatile LHRH release is independently controlled by the alpha-adrenergic and neuropeptide Y neuronal systems in the rhesus monkey. Soc Neurosci Abstr. 18:1992;192.
26. Goldsmith PC, Thind KK. Morphological basis for neuronal control of GnRH secretion in the monkey. In: Plant TM, Lee PA, editors. The Neurobiology of Puberty. Bristol: Journal of Endocrinology Ltd, 1995:73-85.
27. Terasawa E, Nyberg CL. LHRH pulse generation in the monkey: in vivo and in vitro studies. In: Maeda KI, Tsukamura H, Yokoyama A, editors. Neural Control of Reproduction: Physiology and Behavior. Tokyo: Japan Scientific Societies Press, 1997:57-70.
28. Nyberg C.L., Saltzman W., Terasawa E. Effect of L-arginine on neuropeptide Y release in vivo in the female rhesus monkey. Soc Neurosci Abstr. 22:1996;958.
29. Terasawa E. Control of luteinizing hormone-releasing hormone pulse generation in nonhuman primates. Cell Mol Neurobiol. 15:1995;141-164.
30. Mellon P.L., Windle J.J., Goldsmith P.C., Padula C.A., Roberts J.L., Weiner R.I. Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron. 5:1990;1-10.
31. Martinez de la Escalera G., Choi A.L.H., Weiner R.I. Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: intrinsic properties of the GT1-1 GnRH neuronal cell line. Proc Natl Acad Sci USA. 89:1992;1852-1855.
32. Krsmanovic L.Z., Stojilkovic S.S., Merelli F., Dufour S.M., Virmani M.A., Catt K.J. Calcium signaling and episodic secretion of gonadotropin-releasing hormone in hypothalamic neurons. Proc Natl Acad Sci USA. 89:1992;8462-8466.
33. Krsmanovic L.Z., Stojilkovic S.S., Mertz L.M., Tomic G., Catt K.J. Expression of gonadotropin-releasing hormone receptors and autocrine regulation of neuropeptide release in immortalized hypothalamic neurons. Proc Natl Acad Sci USA. 90:1993;3908-3912.
34. 2+ oscillations in LHRH neurons derived from embryonic olfactory placode of the rhesus monkey. Soc Neurosci Abstr. 23:1997;27.
35. Pau K.-Y.F., Berria M., Hess D.L., Spies H.G. Hypothalamic site-dependent effects of neuropeptide Y on gonadotropin-releasing hormone secretion in rhesus macaques. J Neuroendocrinol. 7:1995;63-67.