Subunit composition and novel localization of K+ channels in spinal cord

Journal of Comparative Neurology

Volumn 429, Issue 1, 2001, Pages 166-176

  Rasband, Matthew N ^a   Trimmer, James S ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Caspr; Kv1 K+ channels; Myelin; Na+ channels; Node of Ranvier; Spinal cord injury

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROTEIN SUBUNIT; SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MYELINATED NERVE; NERVE CONDUCTION; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RANVIER NODE; RAT; SENSORIMOTOR FUNCTION; SPINAL CORD; SPINAL CORD FUNCTION; SPINAL CORD INJURY;

ANIMALS; CATTLE; HUMANS; KV1.1 POTASSIUM CHANNEL; KV1.2 POTASSIUM CHANNEL; NERVE FIBERS, MYELINATED; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RANVIER'S NODES; RATS; SPINAL CORD;

EID: 0035218139     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9861(20000101)429:1<166::AID-CNE13>3.0.CO;2-Y     Document Type: Article

References (45)

1. Generation and characterization of subtype-specific monoclonal antibodies to K+ channel alpha- and beta-subunit polypeptides
2. Effect of 4-aminopyridine on axonal conduction-block in chronic spinal cord injury
3. The effects of 4-aminopyridine on neurological deficits in chronic cases of traumatic spinal cord injury in dogs: A phase I clinical trial
4. Potassium channels in nodal and internodal axonal membrane of mammalian myelinated fibres
5. Evidence for the presence of potassium channels in the paranodal region of acutely demyelinated mammalian single nerve fibres
6. Subunit composition of Kv1 channels in human CNS
7. Axo-glial interactions regulate the localization of axonal paranodal proteins
8. The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination
9. Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibers
10. Evidence for the presence of two types of potassium channels in the rat optic nerve
11. Pharmacological sensitivities of two after hyperpolarizations in rat optic nerve
12. 4-Aminopyridine enhances motor evoked potentials following graded spinal cord compression injury in rats
13. 4-Aminopyridine sensitive neurologic deficits in patients with spinal cord injury
14. Delayed depolarization and slow sodium currents in cutaneous afferents
15. Properties of voltage-gated K+ currents expressed in Xenopus oocytes by mKv1.1, mKv1.2 and their heteromultimers as revealed by mutagenesis of the dendrotoxin-binding site in mKv1.1
16. Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes
17. Aminopyridine-sensitivity of spinal cord white matter studied in vitro
18. Absence of potassium conductance in central myelinated axons
19. Mammalian optic nerve fibers display two pharmacologically distinct potassium channels
20. Differential distribution of closely related potassium channels in rat Schwann cells
21. Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits
22. Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions
23. Sustained improvements in neurological function in spinal cord injured patients treated with oral 4-aminopyridine: Three cases
24. Ion channel sequestration in central nervous system axons
25. Potassium channel distribution, clustering, and function in remyelinating rat axons
26. Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS
27. K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve
28. Association and colocalization of K+ channel alpha- and beta-subunit polypeptides in rat brain
29. Voltage-gated K+ channel beta subunits: Expression and distribution of Kv beta 1 and Kv beta 2 in adult rat brain
30. Association and colocalization of the Kvbeta1 and Kvbeta2 beta-subunits with Kv1 alpha-subunits in mammalian brain K+ channel complexes
31. Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibres
32. Membrane specialization at the nodes of Ranvier and paranodal and juxtaparanodal regions of myelinated central and peripheral nerve fibers
33. Heteromultimeric channels formed by rat brain potassium-channel proteins
34. Action potentials and membrane currents in the human node of Ranvier Pflugers Arch
35. Safety and efficacy of 4-aminopyridine in humans with spinal cord injury: A long-term, controlled trial
36. Differential effects of low and high concentrations of 4-aminopyridine on axonal conduction in normal and injured spinal cord
37. Properties of Kv2.1 K+ channels expressed in transfected mammalian cells
38. Beta subunits promote K+ channel surface expression through effects early in biosynthesis
39. Deletion of the K(V)1.1 potassium channel causes epilepsy in mice
40. Immunological identification and characterization of a delayed rectifier K+ channel polypeptide in rat brain
41. Dynamic potassium channel distributions during axonal development prevent aberrant firing patterns
42. Alpha subunit compositions of Kv1.1-containing K+ channel subtypes fractionated from rat brain using dendrotoxins
43. Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons
44. Hypomyelination alters K+ channel expression in mouse mutants shiverer and trembler
45. Specific alteration of spontaneous GABAergic inhibition in cerebellar Purkinje cells in mice lacking the potassium channel Kv1.1