Chlorzoxazone or 1-EBIO increases Na+ absorption across cystic fibrosis airway epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 281, Issue 5 25-5, 2001, Pages

  Gao, Lin ^a   Yankaskas, James R ^b   Fuller, Catherine M ^c   Sorscher, Eric J ^c,d   Matalon, Sadis ^c,e,f   Forman, Henry J ^a   Venglarik, Charles J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d University of Alabama at Birmingham   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

1 ethyl 2 benzimidazolinone; Amiloride; Clotrimazole; Cystic fibrosis transmembrane conductance regulator; Epithelial sodium channel

Indexed keywords

1 ETHYL 2 BENZIMIDAZOLINONE; AMILORIDE; AMPHOTERICIN B; CHLORZOXAZONE; CLOTRIMAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; FEMALE; MEMBRANE TRANSPORT; NONHUMAN; OOCYTE; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SODIUM ABSORPTION; XENOPUS;

EID: 0035199690     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.281.5.l1123     Document Type: Article

References (39)

1. Improved oxygenation promotes CFTR maturation and trafficking in MDCK monolayers
2. Molecular characteristics of amiloride-sensitive sodium channels
3. Effect of amiloride and some of its analogues of cation transport in isolated frog skin and thin lipid membranes
4. + transport in a high-resistance clone of the MDCK cell line
5. Epithelial cell dysfunction in cystic fibrosis: Implications for airways disease
6. + channels in murine colonic epithelia by 1-ethyl-2-benzimidazolone
7. Basolateral K conductance: Role in regulation of NaCl absorption and secretion
8. Pharmacological modulation of ion transport across wild-type and ΔF508 CFTR-expressing human bronchial epithelia
9. K
10. + channel
11. + channels
12. Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells
13. + currents in Xenopus oocytes expressing αβγ-rENaC
14. Synthetic chloride channel restores glutathione secretion in cystic fibrosis airway epithelia
15. Abnormal glutathione transport in cystic fibrosis airway epithelia
16. Pharmacology of potassium channels
17. Resting and osmotically induced basolateral K conductances in turtle colon
18. Differentiation of two distinct K conductances in the basolateral membrane of turtle colon
19. + channel in the mouse jejunum
20. The combinations of haemoglobin with oxygen and carbon monoxide
21. Basolateral potassium channel in turtle colon. Evidence for single-file ion flow
22. The nature of the frog skin potential
23. + replacement in cystic fibrosis
24. + conductances in airway epithelial cells
25. - secretion in murine nasal and colonic epithelia
26. 2+-dependent
27. Role of CFTR in airway disease
28. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
29. - secretion by polarized monolayers of human colonic epithelial cells
30. - secretion by chlorzoxazone
31. Benzimidazolone activators of chloride secretion: Potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease
32. CFTR as a cAMP-dependent regulator of sodium channels
33. + channels
34. Cholinergic regulation of Na absorption by turtle colon: Role of basolateral K conductance
35. - channels
36. Voltage dependence of the blocking rate constants of amiloride at apical Na channels
37. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
38. Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype