The role of exocytosis in the activation of the chloride conductance in Chinese hamster ovary cells (CHO) stably expressing CFTR

Pflugers Archiv European Journal of Physiology

Volumn 434, Issue 6, 1997, Pages 779-784

  Hug, M J ^a   Thiele, I E ^a   Greger, R ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Ca2+ activated Cl channel; CFTR; Cl channel; Cystic fibrosis; Exocytosis

Indexed keywords

CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CELL LEVEL; CHANNEL GATING; CHLORIDE CONDUCTANCE; CHO CELL; EXOCYTOSIS; FEMALE; MEMBRANE CURRENT; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CHLORIDE CHANNELS; CHO CELLS; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ELECTRIC CONDUCTIVITY; EXOCYTOSIS; FEMALE; FORSKOLIN; MUTATION; OVARY;

EID: 0031424985     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050465     Document Type: Article

References (20)

1. 29 cells. Pflügers Arch 421:403-405
2. Bradbury NA, Jilling T, Berta G, Sorscher EJ, Bridges RJ, Kirk KL (1992) Regulation of plasma membrane recycling by CFTR. Science 256:530-532
3. Fuller CM, Benos DJ (1992) CFTR! Am J Physiol 267: C267-C287
4. Gadsby DC, Nagel G, Hwang TC (1995) The CFTR chloride channel of mammalian heart. Annu Rev Physiol 57:387-416
5. 29 cells. Pflügers Arch 424:329-334
6. Greger R, Mall M, Bleich M, Ecke D, Warth R, Riedemann N, Kunzelmann K (1996) Regulation of epithelial ion channels by the cystic fibrosis transmembrane conductance regulator (CFTR). J Mol Med 74:527-534
7. Greger R, Bleich M, Leipziger J, Mall M, Ecke D, Kunzelmann K (1997) Regulation of colonic ion transport. News Physiol Sci 12:62-66
8. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100
9. 29). Pflügers Arch 410:487-494
10. - movements in human colonic epithelial cells (HT29-Cl.16E). Biochem J 304:675-678
11. 29 colon carcinoma cells. Pflügers Arch 421:230-237
12. + channels in Xenopus oocytes. FEES Lett 381:47-52
13. + conductance. Pflügers Arch 432:516-522
14. 2+ spikes directly triggering exocytotic secretion in exocrine pancreas. EMBO J 12:3017-3022
15. + channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proc Natl Acad Sci USA 93:8083-8088
16. Morris AP, Frizzell RA (1994) Vesicle targeting and ion secretion in epithelial cells: implications for cystic fibrosis. Annu Rev Physiol 56:371-397
17. Riordan JR (1993) The cystic fibrosis transmembrane conductance regulator. Annu Rev Physiol 55:609-630
18. Rohlicek V, Schmid A (1994) Dual-frequency method for synchronous measurement of cell capacitance, membrane conductance and access resistance on single cells. Pflügers Arch 428: 30-38
19. Schreiber R, Greger R, Kunzelmann K (1997) Cystic fibrosis transmembrane conductance regulator activates water conductance in Xenopus oocytes. Pflügers Arch (in press)
20. - channel in CHO cells stably expressing the cystic fibrosis gene. Nature 352:628-631