Entropy as the predominant driving force of binding to human recombinant αxβ3γ2 GABAA receptors

European Journal of Pharmacology

Volumn 411, Issue 1-2, 2001, Pages 55-60

  Maksay, Gábor ^a   McKernan, Ruth ^b  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Entropy change; GABAA receptor agonist; GABAA receptor antagonist; GABAA receptors; Recombinant; Thermodynamics

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 PIPERIDINESULFONIC ACID; GABOXADOL; MUSCIMOL; RECEPTOR SUBUNIT; RECOMBINANT RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LINE; DRUG EFFICACY; DRUG RECEPTOR BINDING; ENTROPY; IC 50; MOUSE; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

ANIMALS; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTROPY; GABA AGONISTS; GABA ANTAGONISTS; HUMANS; ISOXAZOLES; L CELLS (CELL LINE); MEMBRANES; MICE; MUSCIMOL; PIPERIDINES; PYRIDAZINES; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; TEMPERATURE; TRITIUM;

EID: 0035190525     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00898-0     Document Type: Article

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