Xenobiotic considerations for the development of autoimmune liver diseases: Bad genes and bad luck

Reviews on Environmental Health

Volumn 16, Issue 3, 2001, Pages 191-202

  He, X S ^a   Ansari, A A ^a   Gershwin, M E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autoimmune hepatitis; Cytochrome P450 family; Primary biliary cirrhosis

Indexed keywords

AUTOANTIBODY; CYTOCHROME P450; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE HEPATITIS; CELLULAR IMMUNITY; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; HOST; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOLOGY; LIVER DISEASE; MOUSE; NONHUMAN; PRIMARY BILIARY CIRRHOSIS;

EID: 0035189228     PISSN: 00487554     EISSN: None     Source Type: Journal    
DOI: 10.1515/REVEH.2001.16.3.191     Document Type: Article

References (46)

1. Familial primary biliary cirrhosis in Hiroshima
2. The geoepidemiology of primary biliary cirrhosis: Contrasts and comparisons with the spectrum of autoimmune diseases
3. Genetic and familial considerations of primary biliary cirrhosis
4. Primary biliary cirrhosis: An epidemiological study
5. The epidemiology of primary biliary cirrhosis: Immunological problems
6. Low prevalence of primary biliary cirrhosis in Victoria, Australia
7. The basis of autoimmunity: Part 1. Mechanisms of aberrant self-recognition
8. Environmentally induced autoimmune diseases: Potential mechanisms
9. Autoimmunity. Thoughts for the millennium
10. Allergic and autoimmune reactions to xenobiotics: How do they arise?
11. Target proteins in human autoimmunity: Cytochromes P450 and UDP-glucuronosyltransferases
12. Mechanisms, chemical structures and drug metabolism
13. Autoimmune hepatitis: Clinical challenges
14. Recognition of uridine diphosphate glucuronosyl transferases by LKM-3 antibodies in chronic hepatitis D
15. Frequency and significance of antibodies to P450IID6 protein in Japanese patients with chronic hepatitis C
16. Absence of LKM-1 antibody reactivity in autoimmune and hepatitis-C-related chronic liver disease in Sweden
17. Relation between autoimmune liver diseases and viral hepatitis: Clinical and serological characteristics in 859 patients
18. Type 2 autoimmune hepatitis and hepatitis C virus infection
19. Hepatitis C viraemia in adults with type 2 autoimmune hepatitis
20. Hepatitis C virus-related chronic liver disease with autoantibodies to liver-kidney microsomes (LKM). Clinical characterization from idiopathic LKM-positive disorders
21. LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 mono-oxygenase
22. Analysis of rearranged T cell receptor (TCR) V beta transcripts in livers of primary biliary cirrhosis: Preferential V beta usage suggests antigen-driven selection
23. Clonal analysis of liver-infiltrating T cells in patients with LKM-1 antibody-positive autoimmune chronic active hepatitis
24. Autoreactive CD4 + LKM-specific and anticlonotypic T-cell responses in LKM-1 antibody-positive autoimmune hepatitis
25. Evidence for the targeting by 2-oxo-dehydrogenase enzymes in the T-cell response of primary biliary cirrhosis
26. Identification and precursor frequency analysis of a common T-cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis
27. Antibodies have the intrinsic capacity to destroy antigens
28. Primary biliary cirrhosis: An orchestrated immune response against epithelial cells
29. Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae
30. Breaking tolerance leads to autoantibody production but not autoimmune liver disease in hepatitis B virus envelope transgenic mice
31. Break of T-cell ignorance to a viral antigen in the liver induces hepatitis
32. B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice
33. Molecular mimicry and autoimmune disease
34. Virus-induced autoimmune disease
35. Structure of human T-cell receptors specific for an immunodominant myelin basic protein peptide: Positioning of T-cell receptors on HLA-DR2/peptide complexes
36. Myelin basic protein and human coronavirus 229E cross-reactive T cells in multiple sclerosis
37. A cartilage-mimicking T-cell epitope on a 65K mycobacterial heat-shock protein: Adjuvant arthritis as a model for human rheumatoid arthritis
38. Separation of IL-4 production from Th cell proliferation by an altered T-cell receptor ligand
39. Changes in cytokine secretion induced by altered peptide ligands of myelin basic protein peptide 85-99
40. Molecular mimicry of human cytochrome P450 by hepatitis C virus at the level of cytotoxic T-cell recognition
41. Polyclonality and multispecificity of the CTL response to a single viral epitope
42. Risk factors for primary biliary cirrhosis in a cohort of patients from the United States
43. Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T-cell epitope of primary biliary cirrhosis
44. Immunotherapy of chronic hepatitis B by anti HBV vaccine: From present to future
45. The staphylococcal enterotoxins and their relatives
46. Superantigens: Biology, immunology, and potential role in disease