Gene expression profiling of cancer by use of DNA arrays: How far from the clinic?

Lancet Oncology

Volumn 2, Issue 11, 2001, Pages 674-682

  Bertucci, François ^a,b,c   Houlgatte, Rémi ^a,c   Nguyen, Catherine ^a,c   Viens, Patrice ^a,b   Jordan, Bertrand R ^d   Birnbaum, Daniel ^a,c,e  

^a Aix Marseille university   (France)

^b IPC   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d Parc Scientifique de Luminy   (France)

^e INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DNA;

CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER GENETICS; CANCER RESEARCH; CANCER TISSUE; CARCINOGENESIS; DISEASE MANAGEMENT; DNA MICROARRAY; DRUG DEVELOPMENT; FUTUROLOGY; GENE EXPRESSION; GENE TARGETING; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MEDICAL TECHNOLOGY; MEDICINE; MOLECULAR BIOLOGY; MOLECULAR GENETICS; PRIORITY JOURNAL; PROGNOSIS; REVIEW;

EID: 0035182884     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(01)00557-5     Document Type: Review

References (64)

1. Estimates of the worldwide incidence of 25 major cancers in 1990
2. Estimates of the worldwide mortality from 25 cancers in 1990
3. Status of bcr-abl tyrosine kinase inhibitors in chronic myelogenous leukemia
4. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
5. The Chipping Forecast
6. Differential gene expression in the murine thymus assayed by quantitative hybridization of arrayed cDNA clones
7. Expression profiling: DNA arrays in many guises
8. Expression scanning of an array of growth control genes in human tumor cell lines
9. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
10. Sensitivity issues in DNA array-based expression measurements and performance of nylon microarrays for small samples
11. Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection
12. Expression monitoring by hybridization to high-density oligonucleotide arrays
13. Cluster analysis and display of genome-wide expression patterns
14. Expression analysis with oligonucleotide mircoarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
15. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
16. Differential gene expression in mouse mammary adenocarcinomas in the presence and absence of wild type p53
17. Functional discovery via a compendium of expression profiles
18. Systematic determination of genetic network architecture
19. Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancer
20. In vivo gene expression profile analysis of human breast cancer progression
21. Identification by cDNA microarray of genes involved in ovarian carcinogenesis
22. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer
23. Classification of small cell lung cancer and pulmonary carcinoid by gene expression profiles
24. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
25. Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture microdissection and cDNA arrays
26. Genomic analysis of metastasis reveals an essential role for RhoC
27. Gene-expression profiles in hereditary breast cancer
28. Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics
29. Identification and temporal expression pattern of genes modulated during irreversible growth arrest and terminal differentiation in human melanoma cells
30. Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray
31. Discovery of differentially expressed genes associated with paclitaxel resistance using cDNA array technology: Analysis of interleukin (IL) 6, IL-8, and monocyte chemotactic protein 1 in the paclitaxel-resistant phenotype
32. Pleiotropic resistance to DNA-interactive drugs is associated with increased expression of genes involved in DNA replication, repair, and stress response
33. A gene expression database for the molecular pharmacology of cancer
34. Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
35. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays
36. Systematic variation in gene expression patterns in human cancer cell lines
37. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
38. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
39. Gene expression profiling of primary breast carcinomas using arrays of candidate genes
40. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
41. Molecular portraits of human breast tumours
42. Linking gene expression patterns to therapeutic groups in breast cancer
43. Molecular classification of cutaneous malignant melanoma by gene expression profiling
44. Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array
45. The sequence of the human genome
46. Initial sequencing and analysis of the human genome
47. Laser capture microdissection
48. Genes expressed in human tumor endothelium
49. Gene expression profiles of laser-captured adjacent neuronal subtypes
50. High-fidelity mRNA amplification for gene profiling
51. Identification of changes in gene expression associated with minimal residual disease
52. Analysis of large-scale gene expression data
53. One-stop shop for microarray data
54. Keeping genome databases clean and up to date
55. Tissue microarrays for high-throughput molecular profiling of tumor specimens
56. Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays
57. High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma
58. Large-scale identification, mapping, and genotyping of single- nucleotide polymorphisms in the human genome
59. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
60. Messenger RNA translation state: The second dimension of high-throughput expression screening
61. An approach to proteomic analysis of human tumors
62. Protein microarrays for gene expression and antibody screening
63. Future trends in diagnosis using laboratory-on-a-chip technologies
64. Portable system for microbial sample preparation and oligonucleotide microarray analysis