dlk inhibits stem cell factor-induced colony formation of murine hematopoietic progenitors: Hes-1-independent effect

Stem Cells

Volumn 19, Issue 1, 2001, Pages 71-79

  Ohno, Noriko ^a   Izawa, Akiko ^a   Hattori, Masakazu ^b   Kageyama, Ryoichiro ^b   Sudo, Tetsuo ^a  

^a TORAY INDUSTRIES INC   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Colony formation; dlk; Hematopoiesis; Hes 1; Pref 1; Stem cell factor

Indexed keywords

CHIMERIC PROTEIN; COLONY STIMULATING FACTOR 1; DELTA LIKE PROTEIN; EPIDERMAL GROWTH FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH INHIBITOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 3; MEMBRANE PROTEIN; STEM CELL FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL INTERACTION; COLONY FORMATION; HEMATOPOIETIC STEM CELL; MALE; MOUSE; NONHUMAN; NULL CELL; STROMA CELL; THYMOCYTE;

ANIMALIA; MURINAE;

EID: 0035181767     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.19-1-71     Document Type: Article

References (53)

1. Regulatory mechanisms in stem cell biology
2. Differentiation and proliferation of hematopoietic stem cells
3. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
4. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species
5. Notch signaling
6. Signalling downstream of activated mammalian Notch
7. Inhibition of granulocytic differentiation by mNotch1
8. The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
9. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
10. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
11. + hematopoietic precursors
12. An activated form of Notch influences the choice between CD4 and CD8 T cell lineage
13. Notch activity influences the αβ versus γδ T cell lineage decision
14. Delta-1 activation of Notch-1 signaling results in HES-1 transactivation
15. The bHLH gene Hes1 is essential for expansion of early T cell precursors
16. Notch as mediator of cell fate determination in hematopoiesis: Evidence and speculation
17. Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta
18. Mouse Dll3: A novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo
19. Isolation and function analysis of a cDNA for human Jagged2, a gene encoding a lig- and for the Notch1 receptor
20. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
21. Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells
22. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
23. The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro
24. A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells
25. Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1
26. Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs
27. dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line
28. Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
29. Cleavage of membrane-associated pref-1 generates a soluble inhibitor of adipocyte differentiation
30. Protein structure of fetal antigen 1 (FA1), a novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2
31. Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans
32. Modulated expression of the epidermal growth factor-like homeotic protein dlk influences stromal-cell-pre-B-cell interactions, stromal cell adipogenesis, and pre-B-cell interlukin-7 requirements
33. A role for Pref-1 and HES-1 in thymocyte development
34. A new preadipose cell line derived from newborn mouse calvaria can promote the proliferation of pluripotent hematopoietic stem cells in vitro
35. Expression and characterization of human CD4: Immunoglobulin fusion proteins
36. Expression and function of the Interleukin 7 receptor in murine lymphocytes
37. Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M
38. Targeted disruption of mammalian hairy and enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects
39. Purification and characterizations of mouse hematopoietic stem cells
40. A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1α
41. Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture
42. Distinct and overlapping direct effects of macrophage inflammatory protein-1α and transforming growth factor β on hematopoietic progenitor/stem cell growth
43. Tumor necrosis factor (TNF) is a physiologic regulator of hematopoietic progenitor cells: Increase of early hematopoietic progenitor cells in TNF receptor p55-deficient mice in vivo and potent inhibition of progenitor cell proliferation by TNFα in vitro
44. Studies of interferon as a regulator of hematopoietic cell proliferation
45. Transforming growth factor-β regulates c-kit message stability and cell-surface protein expression in hematopoietic progenitors
46. Transforming growth factor β1 selectively regulates and inhibits the growth of IL-3-dependent myeloid leukemia cell lines
47. + hematopoietic progenitors to cytokines is determined by the balance between synergy of multiple stimulators and negative cooperation of multiple inhibitors
48. Transforming growth factor-β1 bifunctionally regulates murine macrophage proliferation
49. Expression and function of c-kit in hemopoietic progenitor cells
50. Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system
51. Structure-function analysis of interleukin-5 utilizing mouse/human chimeric molecules
52. Dimerization of B-type platelet-derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation
53. The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors