Smooth muscle cell apoptosis in arteriosclerosis

Experimental Gerontology

Volumn 36, Issue 7, 2001, Pages 969-987

  Mayr, Manuel ^a   Xu, Qingbo ^b  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Aging; Apoptosis; Atherosclerosis; Mechanical stress; Signaling; Smooth muscle cells

Indexed keywords

APOPTOSIS; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL WALL; CELL AGING; CELL DEATH; HUMAN; MECHANICAL STRESS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ANIMALS; APOPTOSIS; ARTERIOSCLEROSIS; HUMANS; LIPOPROTEINS, LDL; MUSCLE, SMOOTH, VASCULAR;

EID: 0034992603     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(01)00090-0     Document Type: Review

References (94)

1. The p53 network
2. Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth
3. Apoptosis in restenosis versus stable-angina atherosclerosis: implications for the pathogenesis of restenosis
4. Apoptosis of vascular smooth muscle cells in atherosclerosis
5. Apoptosis of human smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques
6. Increased sensitivity of human vascular smooth muscle cells from atherosclerotic plaques to p53-mediated apoptosis
7. Cell surface trafficking of Fas: a rapid mechanism of p53 mediated apoptosis
8. Mechanism of shear-induced prostacyclin production in endothelial cells
9. Apoptosis is abundant in human atherosclerotic lesions, especially in inflammatory cells (macrophages and T cells), and may contribute to the accumulation of gruel and plaque instability
10. The pro-apoptotic Bcl-2 family member, Bax
11. Vascular remodeling in response to altered blood flow is mediated by fibroblast growth factor-2
12. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
13. Sensitivity to Fas-mediated apoptosis is determined below receptor level in human vascular smooth muscle cells
14. p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage
15. Flow-mediated endothelial mechanotransduction
16. Smooth muscle apoptosis during vascular regression in spontaneously hypertensive rats
17. Rapid development of vein graft atheroma in ApoE-deficient mice
18. Nuclear changes in apoptosis
19. Oxidized LDLs induce massive apoptosis of cultured human endothelial cells through calcium-dependent pathway: prevention by aurintricarboxylic acid
20. Evidence for apoptosis in advanced human atheroma
21. Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells
22. Smooth muscle cell origin and its relation to heterogeneity in development and disease
23. Apoptosis: molecular aspects of cell death and disease
24. Gone but not forgotten
25. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
26. NAD(P)H oxidase: role in cardiovascular biology and disease
27. Apoptosis and vascular remodeling in hypertension
28. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model
29. Apoptosis: basic mechanisms and implications for cardiovascular disease
30. A monocyte chemotactic factor, S19 ribosomal protein dimer, in phagocytic clearance of apoptotic cells
31. p53, p21(WAF1/CIP1), and MDM2 involvement in proliferation and apoptosis in an in vitro model of conditionally immortalized human vascular smooth muscle cells
32. 2-terminal protein kinases in tissues of heat-stressed mice
33. Inhibition of neointima hyperplasia of mouse vein grafts by locally applied suramin
34. Cystic medial degeneration of the aorta is associated with p53 accumulation, Bax upregulation, apoptotic cell death, and cell proliferation
35. Apoptosis in human atherosclerosis and restenosis
36. Lack of hemodynamic forces triggers apoptosis in vascular endothelial cells
37. Apoptosis and regulation of bax and bcl-X proteins during human neonatal vascular remodeling
38. Apoptosis in the atherosclerotic plaque
39. Apoptosis in atherosclerosis: beneficial or detrimental?
40. Foam cell replication and smooth muscle cell apoptosis in human saphenous vein grafts
41. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
42. Insulin-like growth factor-1 induces mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis
43. Apoptosis of vascular smooth muscle cells: protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells
44. Protein kinase C-alpha regulates proliferation but not apoptosis in rat coronary vascular smooth muscle cells
45. Cyclic strain stress-induced mitogen-activated protein kinase (MAPK) phosphatase 1 expression in vascular smooth muscle cells is regulated by Ras/Rac-MAPK pathways
46. Ras/Rac-dependent activation of p38 mitogen-activated protein kinases in smooth muscle cells stimulated by cyclic strain stress
47. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity
48. Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells
49. Biomechanical stress-induced apoptosis in vein grafts involves p38 mitogen-activated protein kinases
50. The regulation of vascular smooth muscle cell apoptosis
51. Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins
52. Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in atherosclerotic lesions coincide with p53
53. p53 phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1
54. Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand
55. Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, prevention
56. Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells
57. S19 ribosomal protein cross-linked dimer causes monocyte-predominant infiltration by means of molecular mimicry to complement C5a
58. Shear stress and cyclic strain modulation of gene expression in vascular endothelial cells
59. Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury
60. Extracellular adenosine induces apoptosis of human arterial smooth muscle cells via A2b-purinoceptor
61. Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease
62. Determinants of vascular smooth muscle cell apoptosis after balloon angioplasty injury: influence of redox state and cell phenotype
63. Apoptosis regulates human vascular calcification in vitro
64. Clustering of apoptotic cells via bystander killing by peroxides
65. The pathogenesis of atherosclerosis: a perspective for the 1990s
66. Flow-induced release of endothelium-derived relaxing factor
67. Recognition of oxidatively damaged and apoptotic cells by an oxidised low density lipoprotein receptor on mouse peritoneal macrophages
68. Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T-cell response
69. Release of active tissue factor by human arterial smooth muscle cells
70. Differential effects of low density lipoproteins on insulin-like growth factor-1 (IGF-1) and IGF-1 receptor expression in vascular smooth muscle cells
71. p53 gene transfer to the injured rat carotid artery promotes apoptosis
72. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity
73. Vitamin C protects human arterial smooth muscle cells against atherogenic lipoproteins: effects of antioxidant vitamins C and E on oxidized LDL-induced adaptive increases in cystine transport and glutathione
74. Vitamin C protects human vascular smooth muscle cells against apoptosis induced by moderately oxidized LDL containing high levels of lipid hydroperoxides
75. Differentiation, dedifferentiation, and apoptosis of smooth muscle cells during the development of the human ductus arteriosus
76. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis
77. Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults
78. Nifedipine induces apoptosis in cultured vascular smooth muscle cells from sponaneously hypertensive rats
79. Lipoproteins and atherogenesis: current concepts
80. Effects of human cytomegalovirus immediated-early proteins on p53-mediated apoptosis in coronary artery smooth muscle cells
81. Smooth muscle cells: another source of tissue factor-containing microparticles in atherothrombosis
82. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
83. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells
84. Susceptibility to apoptosis measured by myc, bcl-2, and bax expression in arterioles and capillaries of adult spontaneously hypertensive rats
85. The blood vessel wall as an insulin target tissue
86. Pathologic changes in aortic-coronary arterial saphenous vein grafts
87. Alteration of carotid atherosclerotic plaque composition in apoE-/- mice by adenoviral transfer of p53
88. Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical applications
89. Biomechanical stress-induced signaling and gene expression in the development of arteriosclerosis
90. Nitric oxide induces heat-shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1
91. Inhibitory effect of bcl-2 on p53-mediated transactivation following genotoxic stress
92. Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy
93. Mouse model of venous bypass graft arteriosclerosis
94. Reduced neointima hyperplasia of vein bypass grafts in intercellular adhesion molecule-1-deficient mice