Non-immunogenic murine hepatocellular carcinoma Hepa 1-6 cells expressing the membrane form of macrophage colony stimulating factor are rejected in vivo and lead to CD8+ T-cell immunity against the parental tumor

Molecular Therapy

Volumn 4, Issue 5, 2001, Pages 427-437

  Dan, Qinghong ^a,b   Sanchez, Ramon ^a,b   Delgado, Christina ^a,b   Wepsic, H Terry ^a,b   Morgan, Kengathevy ^a,c   Chen, Yijun ^a,b   Jeffes, Edward W B ^a,c   Lowell, Clifford A ^d   Morgan, Timothy R ^a,c   Jadus, Martin R ^a,b  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cytotoxic T lymphocytes; Hepatoma; Macrophages; Nitric oxide; Phagocytosis; Tumor immunity

Indexed keywords

CD8 ANTIGEN; RECOMBINANT COLONY STIMULATING FACTOR 1; TUMOR VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER IMMUNOTHERAPY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; GENE EXPRESSION; GENETIC CODE; GENETIC TRANSDUCTION; IMMUNE RESPONSE; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIVER CELL CARCINOMA; MACROPHAGE; MELANOMA B16; MELANOMA CELL; MOUSE; NONHUMAN; PHAGOCYTOSIS; SPLEEN CELL; TUMOR GROWTH; VACCINATION;

ANIMALIA; MURINAE;

EID: 0035178929     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0477     Document Type: Article

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