Correction of radioresistant DNA synthesis in ataxia telangiectasia fibroblasts by prostaglandin E2 treatment

Environmental and Molecular Mutagenesis

Volumn 38, Issue 2-3, 2001, Pages 191-199

  Mirzayans, Razmik ^a   Paterson, Malcolm C ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Conditioned culture medium; Growth factors; Intercellular communication; Interleukin 1; S phase checkpoint

Indexed keywords

ATM PROTEIN; CALCIUM ION; DNA; PROSTAGLANDIN E2; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ARTICLE; ATAXIA TELANGIECTASIA; CALCIUM MOBILIZATION; CELL CYCLE; CELL CYCLE S PHASE; CLINICAL FEATURE; COCULTURE; DNA REPLICATION; DNA SYNTHESIS; FIBROBLAST CULTURE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOSIS INHIBITION; PHENOTYPE; PROTEIN EXPRESSION; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0035174467     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.1071     Document Type: Article

References (62)

1. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles
2. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells
3. The versatility and universality of calcium signalling
4. Multiple ATM-dependent pathways: An explanation for pleiotropy
5. Mammalian DNA mismatch repair
6. Piecing together the p53 puzzle
7. Multiple mechanisms account for genomic instability and molecular mutation in neoplastic transformation
8. Effects of the protein kinase inhibitors wortmannin and KN62 on cellular radiosensitivity and radiation-activated S phase and G1/S checkpoints in normal human fibroblasts
9. Relationship between Ras pathways and cell cycle control
10. 2+/calmodulin-dependent protein kinase II in γ-irradiated ataxia telangiectasia fibroblasts
11. Ataxia-telangiectasia: An interdisciplinary approach to pathogenesis
12. Lipoprotein-dependent unsaturated fatty acid transport and metabolism in cultured cells
13. DNA recombination: The replication connection
14. Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis
15. The role of cytokines in radiation oncology
16. Factors underlying the cell growth-related bystander responses to alpha particles
17. The arachidonic acid cascade, eicosanoids, and signal transduction
18. Genetic heterogeneity in ataxia-telangiectasia studied by cell fusion
19. Cancer risk and the ATM gene: A continuing debate
20. Stress-induced secretion of growth inhibitors: A novel tumor suppressor function of p53
21. Molecule of the year: The DNA repair enzyme
22. Epidermal growth factor modification of radioresistance related to cell-cell interactions
23. ATM: The protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia
24. Transcription-coupled repair of DNA damage: Unanticipated players, unexpected complexities
25. Quality control by DNA repair
26. Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene
27. Misoprostol-induced radioprotection of Syrian hamster embryo cells in utero from cell death and oncogenic transformation
28. Defective repair of a class of 4NQO-induced alkali-labile DNA lesions in xeroderma pigmentosum complementation group A fibroblasts
29. Characterization of the signal transduction pathway mediating γ ray-induced inhibition of DNA synthesis in human cells: Indirect evidence for involvement of calmodulin but not protein kinase C nor p53
30. Abnormal pattern of post-γ-ray DNA replication in radioresistant fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome
31. Differential expression and stability of foreign genes introduced into human fibroblasts by nuclear versus cytoplasmic microinjection
32. Faulty DNA polymerase δ/ε-mediated excision repair in response to γ radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome
33. Inhibition of DNA synthesis and G1/S-phase transition in normal human fibroblasts elicited by a heat-labile trans-acting factor in gamma-irradiated HeLa cell extracts
34. Hypersensitivity to cell killing and faulty repair of 1-β-D-arabinofuranosylcytosine-detectable sites in human (ataxia-telangiectasia) fibroblasts treated with 4-nitroquinoline 1-oxide
35. Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: Evidence for release during irradiation of a signal controlling survival into the medium
36. Unexpected sensitivity to the induction of mutations by very low doses of alpha-particle radiation: Evidence for a bystander effect
37. Prostanoid receptors. Structure, function, and distribution
38. Prostanoid receptors and their biological actions
39. Image cytometry system for morphometric measurements of live cells
40. Cancer predisposition, carcinogen hypersensitivity and aberrant DNA metabolism
41. Use of a UV endonuclease from Micrococcus luteus to monitor the progess of DNA repair in UV-irradiated human cells
42. Correction of post-γ ray DNA repair deficiency in ataxia-telangiectasia complementation group A fibroblasts by cocultivation with normal fibroblasts
43. Endonucleolytic activity from Micrococcus luteus that acts on γ-ray-induced damage in plasmid DNA of Escherichia coli minicells
44. Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts
45. Ataxia telangiectasia: An inherited human disorder involving hypersensitivity to ionizing radiation and related DNA-damaging chemicals
46. Arachidonic acid in cell signaling
47. Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens
48. 2 as a "death trigger" in the aging process. The use of PLA2 inhibitors as antiaging substances
49. ATM: A mediator of multiple responses to genotoxic stress
50. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
51. Radioprotective effects of prostaglandins for chromosomal aberrations and cell killing in V79 Chinese hamster cells grown as spheroids in vitro and for mouse spermatogonial stem cells and bone marrow cells in vivo
52. A single ataxia telangiectasia gene with a product similar to PI-3 kinase
53. Cyclobutane-type pyrimidine dimers in polynucleotides
54. Defective repair of gamma-ray induced DNA damage in xeroderma pigmentosum cells
55. A coordinated interplay: Proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription
56. What has the cloning of the ATM gene told us about ataxia telangiectasia?
57. Protein kinases as mediators of phosphoinositide 3-kinase signaling
58. Chromosomal instability in unirradiated cells induced in vivo by a bystander effect of ionizing radiation
59. Defective radiation signal transduction in ataxia-telangiectasia
60. 2 (Nocloprost) on the radiation response of human normal fibroblasts and colon adenocarcinoma cells
61. Induction of a bystander mutagenic effect of alpha particles in mammalian cells