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1
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0028134978
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The SMC family: Novel motor proteins for chromosome condensation?
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Peterson CL. The SMC family: novel motor proteins for chromosome condensation? Cell. 79:1994;389-392.
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Cell
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Peterson, C.L.1
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0029278921
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Coiling up chromosomes
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Gasser SM. Coiling up chromosomes. Curr Biol. 5:1995;357-360.
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Curr Biol
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Gasser, S.M.1
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0029360376
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The SMC proteins and the coming of age of the chromosome scaffold hypothesis
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Saitoh N, Goldberg I, Earnshaw WC. The SMC proteins and the coming of age of the chromosome scaffold hypothesis. BioEssays. 17:1995;759-766.
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(1995)
BioEssays
, vol.17
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Saitoh, N.1
Goldberg, I.2
Earnshaw, W.C.3
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4
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0029081926
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Biochemical and genetic dissection of mitotic chromosome condensation
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Hirano T. Biochemical and genetic dissection of mitotic chromosome condensation. Trends Biochem Sci. 20:1995;357-361.
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Trends Biochem Sci
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Hirano, T.1
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5
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0029038932
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The SMC family: From chromosome condensation to dosage compensation
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Hirano T, Mitchison TJ, Swedlow JR. The SMC family: from chromosome condensation to dosage compensation. Curr Biol. 7:1995;329-336.
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(1995)
Curr Biol
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Hirano, T.1
Mitchison, T.J.2
Swedlow, J.R.3
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7
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0030931080
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Condensins, cohesins, and chromosome architecture: How to make and break a mitotic chromosome
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Heck MMS. Condensins, cohesins, and chromosome architecture: how to make and break a mitotic chromosome. Cell. 91:1997;5-8.
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Cell
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Heck, M.M.S.1
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8
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0001607723
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Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases, and other ATP-requiring enzymes and a common nucleotide binding fold
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Walker JE, Sarasate M, Runswick MJ, Gay NJ. Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases, and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:1982;945-951.
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EMBO J
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Walker, J.E.1
Sarasate, M.2
Runswick, M.J.3
Gay, N.J.4
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9
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0027759461
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SMC1: An essential yeast gene encoding a putative Head-Rod-Tail protein is required for nuclear division and defines a new ubiquitous protein family
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Strunnikov A, Larionov VL, Koshland D. SMC1: an essential yeast gene encoding a putative Head-Rod-Tail protein is required for nuclear division and defines a new ubiquitous protein family. J Cell Biol. 123:1993;1635-1648.
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J Cell Biol
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Strunnikov, A.1
Larionov, V.L.2
Koshland, D.3
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10
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0029782098
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SMC proteins constitute two subunits of the mammalian recombination complex RC-1
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of outstanding interest. Two subunits of the bovine (b) recombination protein complex RC-1 were identified as bSMC1 and bSMC3 proteins and found to be necessary for the DNA transfer reactions mediated by the complex. The bSMC1/3 heterodimer was shown to promote DNA re-annealing.
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Jessberger R, Riwar B, Baechtold H, Akhmedov AT. SMC proteins constitute two subunits of the mammalian recombination complex RC-1. of outstanding interest EMBO J. 15:1996;4061-4068 Two subunits of the bovine (b) recombination protein complex RC-1 were identified as bSMC1 and bSMC3 proteins and found to be necessary for the DNA transfer reactions mediated by the complex. The bSMC1/3 heterodimer was shown to promote DNA re-annealing.
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(1996)
EMBO J
, vol.15
, pp. 4061-4068
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Jessberger, R.1
Riwar, B.2
Baechtold, H.3
Akhmedov, A.T.4
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11
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0027943721
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A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro
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Hirano T, Mitchison TJ. A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell. 79:1994;449-458.
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(1994)
Cell
, vol.79
, pp. 449-458
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Hirano, T.1
Mitchison, T.J.2
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12
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0030830639
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Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila barren protein
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of outstanding interest. A 13S SMC-containing complex promotes chromosome condensation in vitro when added back to a depleted Xenopus egg extract. This condensin contains XCAP-E and XCAp-C (SMC2/4 complex) and polypeptides of 150, 130 and 100 kDa, the last of which is homologous to barren, a Drosophila protein that binds topoisomerase II. Cell-cycle dependent phosphorylation of p150, 130 and X-barren are thought to regulate chromosome binding.
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Hirano T, Kobayashi R, Hirano M. Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila barren protein. of outstanding interest Cell. 89:1997;511-521 A 13S SMC-containing complex promotes chromosome condensation in vitro when added back to a depleted Xenopus egg extract. This condensin contains XCAP-E and XCAp-C (SMC2/4 complex) and polypeptides of 150, 130 and 100 kDa, the last of which is homologous to barren, a Drosophila protein that binds topoisomerase II. Cell-cycle dependent phosphorylation of p150, 130 and X-barren are thought to regulate chromosome binding.
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(1997)
Cell
, vol.89
, pp. 511-521
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Hirano, T.1
Kobayashi, R.2
Hirano, M.3
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13
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0028081446
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Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis
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Saka Y, Sutani T, Yamashita Y, Saitoh S, Takeuchi M, Nakaseko Y, Yanagida M. Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis. EMBO J. 13:1994;4938-4952.
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EMBO J
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Saka, Y.1
Sutani, T.2
Yamashita, Y.3
Saitoh, S.4
Takeuchi, M.5
Nakaseko, Y.6
Yanagida, M.7
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14
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0030885925
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Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
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of outstanding interest. S. cerevisiae scc1, smc1 and smc3 mutants separate sister chromatids prematurely in the absence of elongated spindles. In normal cells, release of SCC1p from chromatin, rather than its degradation, is essential for the onset of anaphase. SCC1p interaction with chromatin requires SMC1p and SMC3p, implicating the three protein in sister chromatin cohesion.
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Michaelis C, Ciosk R, Nasmyth K. Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. of outstanding interest Cell. 91:1997;35-46 S. cerevisiae scc1, smc1 and smc3 mutants separate sister chromatids prematurely in the absence of elongated spindles. In normal cells, release of SCC1p from chromatin, rather than its degradation, is essential for the onset of anaphase. SCC1p interaction with chromatin requires SMC1p and SMC3p, implicating the three protein in sister chromatin cohesion.
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(1997)
Cell
, vol.91
, pp. 35-46
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Michaelis, C.1
Ciosk, R.2
Nasmyth, K.3
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15
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0030886602
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A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
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of outstanding interest. The yeast encoding MCD1p (MCD1 synonymous with SCC1) was isolated as a multi-copy suppressor of a smc1 mutant, suggesting direct interaction. Cytological results indicate that the mcd1 mutant of S. cerevisiae is defective in sister chromatin cohesion and in chromosome condensation.
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Guacci V, Koshland D, Strunnikov A. A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. of outstanding interest Cell. 91:1997;47-58 The yeast encoding MCD1p (MCD1 synonymous with SCC1) was isolated as a multi-copy suppressor of a smc1 mutant, suggesting direct interaction. Cytological results indicate that the mcd1 mutant of S. cerevisiae is defective in sister chromatin cohesion and in chromosome condensation.
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(1997)
Cell
, vol.91
, pp. 47-58
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Guacci, V.1
Koshland, D.2
Strunnikov, A.3
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16
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0028104856
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DPY-27: A chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome
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Chuang PT, Lieb JD, Meyer B. DPY-27: a chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome. Cell. 79:1994;459-474.
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(1994)
Cell
, vol.79
, pp. 459-474
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Chuang, P.T.1
Lieb, J.D.2
Meyer, B.3
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17
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0029807745
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Sex-specific assembly of a dosage compensation complex on the nematode X chromosome
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of outstanding interest. A five polypeptide complex containing the C. elegans SMC4-like protein DPY27, is present in a multicomponent complex that binds selectively to the X chromosomes in hermaphrodite nuclei. This complex contains DPY26, a close relative to the Drosophila barren, DPY28, and possibly SDC3. Specific localization of the chromosome appears to be regulated by sex-determining genes.
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Chuang PT, Lieb JD, Meyer B. Sex-specific assembly of a dosage compensation complex on the nematode X chromosome. of outstanding interest Science. 274:1996;1736-1738 A five polypeptide complex containing the C. elegans SMC4-like protein DPY27, is present in a multicomponent complex that binds selectively to the X chromosomes in hermaphrodite nuclei. This complex contains DPY26, a close relative to the Drosophila barren, DPY28, and possibly SDC3. Specific localization of the chromosome appears to be regulated by sex-determining genes.
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(1996)
Science
, vol.274
, pp. 1736-1738
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Chuang, P.T.1
Lieb, J.D.2
Meyer, B.3
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18
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0028942904
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SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family
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Strunnikov AV, Hogan E, Koshland D. SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes Dev. 9:1995;587-599.
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(1995)
Genes Dev
, vol.9
, pp. 587-599
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Strunnikov, A.V.1
Hogan, E.2
Koshland, D.3
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19
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0028109863
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ScII: An abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure
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Saitoh N, Goldberg IG, Wood ER, Earnshaw WC. ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. J Cell Biol. 127:1994;303-318.
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(1994)
J Cell Biol
, vol.127
, pp. 303-318
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Saitoh, N.1
Goldberg, I.G.2
Wood, E.R.3
Earnshaw, W.C.4
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20
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0025966711
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Chromosome assembly in vitro: Topoisomerase II is required for condensation
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Adachi Y, Luke M, Laemmli UK. Chromosome assembly in vitro: topoisomerase II is required for condensation. Cell. 64:1991;137-148.
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(1991)
Cell
, vol.64
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Adachi, Y.1
Luke, M.2
Laemmli, U.K.3
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21
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0030582717
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Chromatid segregation at anaphase requires the barren product, a novel chromosome associated protein that interacts with topoisoemrase II
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of outstanding interest. The Drosophila melanogaster protein encoded by barren is required for proper mitotic chromosome condensation at anaphase. Mutant barren embryos show a cut-like phenotype in cycle 16: they degrade cyclin B, yet the chromosomes remain uncondensed. Barren binds specifically to DNA topoisomerase II and alters its activity.
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Bhat MA, Philip AV, Glover DM, Bellen HJ. Chromatid segregation at anaphase requires the barren product, a novel chromosome associated protein that interacts with topoisoemrase II. of outstanding interest Cell. 87:1996;1103-1114 The Drosophila melanogaster protein encoded by barren is required for proper mitotic chromosome condensation at anaphase. Mutant barren embryos show a cut-like phenotype in cycle 16: they degrade cyclin B, yet the chromosomes remain uncondensed. Barren binds specifically to DNA topoisomerase II and alters its activity.
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(1996)
Cell
, vol.87
, pp. 1103-1114
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Bhat, M.A.1
Philip, A.V.2
Glover, D.M.3
Bellen, H.J.4
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22
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0030874421
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ATP-dependent positive supercoiling of DNA by 13S condensin: A biochemical implication for chromosome condensation
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of outstanding interest. After treatment with topoisomerase 1, the 13S condensin complex - containing XCAP-C and XCAP-E - is shown to bind preferentially to cruciform or bent DNA and to result in the accumulation of positive supercoils in a circular plasmid. The supercoiling is stoichiometric with the dosage of 13S condensin, but requires ATP, implying an ATP-dependent DNA wrapping activity.
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Kimura K, Hirano T. ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation. of outstanding interest Cell. 90:1997;625-634 After treatment with topoisomerase 1, the 13S condensin complex - containing XCAP-C and XCAP-E - is shown to bind preferentially to cruciform or bent DNA and to result in the accumulation of positive supercoils in a circular plasmid. The supercoiling is stoichiometric with the dosage of 13S condensin, but requires ATP, implying an ATP-dependent DNA wrapping activity.
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(1997)
Cell
, vol.90
, pp. 625-634
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Kimura, K.1
Hirano, T.2
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23
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0029897304
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A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation
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Castano IB, Heath-Pagliuos S, Sadoff BU, Fitzhugh DJ, Christman MF. A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation. Nucleic Acids Res. 24:1996;2404-2410.
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(1996)
Nucleic Acids Res
, vol.24
, pp. 2404-2410
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Castano, I.B.1
Heath-Pagliuos, S.2
Sadoff, B.U.3
Fitzhugh, D.J.4
Christman, M.F.5
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24
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0029999538
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Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae
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of outstanding interest. Mitotic condensation of the repetitive rDNA locus, but not its replication, was found to be defective in a S. cerevisiae top 1 trf4-ts double mutant. Trf4p associates with SMC1p and SMC2p. The data provide evidence for an involvement of topoisomerase I in rDNA condensation.
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Castano IB, Brzoska PM, Sadoff BU, Chen H, Christman MF. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. of outstanding interest Genes Dev. 10:1996;2564-2576 Mitotic condensation of the repetitive rDNA locus, but not its replication, was found to be defective in a S. cerevisiae top 1 trf4-ts double mutant. Trf4p associates with SMC1p and SMC2p. The data provide evidence for an involvement of topoisomerase I in rDNA condensation.
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(1996)
Genes Dev
, vol.10
, pp. 2564-2576
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Castano, I.B.1
Brzoska, P.M.2
Sadoff, B.U.3
Chen, H.4
Christman, M.F.5
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25
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0028850628
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The rad18 gene of Schizosaccharomyces pombe defines a new subgroup if the SMC superfamily involved in DNA repair
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Lehmann AR, Walicka M, Griffiths DJF, Murray JM, Watts FZ, McCready S, Carr AM. The rad18 gene of Schizosaccharomyces pombe defines a new subgroup if the SMC superfamily involved in DNA repair. Mol Cell Biol. 15:1995;7067-7080.
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(1995)
Mol Cell Biol
, vol.15
, pp. 7067-7080
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Lehmann, A.R.1
Walicka, M.2
Griffiths, D.J.F.3
Murray, J.M.4
Watts, F.Z.5
McCready, S.6
Carr, A.M.7
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26
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0027320551
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A mammalian protein complex that repairs double-strand breaks and deletions by recombination
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Jessberger R, Podust V, Hübscher U, Berg P. A mammalian protein complex that repairs double-strand breaks and deletions by recombination. J Biol Chem. 268:1993;15070-15079.
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(1993)
J Biol Chem
, vol.268
, pp. 15070-15079
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Jessberger, R.1
Podust, V.2
Hübscher, U.3
Berg, P.4
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27
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0028308710
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Homologous pairing and DNA strand-exchange proteins
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Kowalczykowski SC, Eggleston AK. Homologous pairing and DNA strand-exchange proteins. Annu Rev Biochem. 63:1994;991-1043.
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(1994)
Annu Rev Biochem
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Kowalczykowski, S.C.1
Eggleston, A.K.2
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28
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0027059030
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Cloning and characterization of rad21, an essential gene of Schizosaccharomyces pombe involved in DNA double-strand break repair
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Birkenbihl RP, Subramani S. Cloning and characterization of rad21, an essential gene of Schizosaccharomyces pombe involved in DNA double-strand break repair. Nucleic Acids Res. 20:1992;6605-6611.
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(1992)
Nucleic Acids Res
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Birkenbihl, R.P.1
Subramani, S.2
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29
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0030826133
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DNA renaturation activity of the SMC complex implicated in chromosome condensation
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of outstanding interest. S. pombe cut3 and cut14 mutant chromosomes remain uncondensed in mitosis. The Cut3/Cut14 protein heterodimer was found to promote efficient DNA reannealing, a process hypothesized to contribute to DNA coiling observed in condensed chromosomes.
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Sutani T, Yanagida M. DNA renaturation activity of the SMC complex implicated in chromosome condensation. of outstanding interest Nature. 388:1997;798-801 S. pombe cut3 and cut14 mutant chromosomes remain uncondensed in mitosis. The Cut3/Cut14 protein heterodimer was found to promote efficient DNA reannealing, a process hypothesized to contribute to DNA coiling observed in condensed chromosomes.
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(1997)
Nature
, vol.388
, pp. 798-801
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Sutani, T.1
Yanagida, M.2
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30
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0029561761
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SARs are cis DNA elements of chromosome dynamics: Synthesis of a SAR repressor protein
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Strick R, Laemmli UK. SARs are cis DNA elements of chromosome dynamics: synthesis of a SAR repressor protein. Cell. 83:1995;1137-1148.
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(1995)
Cell
, vol.83
, pp. 1137-1148
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Strick, R.1
Laemmli, U.K.2
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31
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0003165637
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DNA ligases
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Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
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Nash R, Lindahl T. DNA ligases. DNA Replication in Eukaryotic Cells. 1996;575-586 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
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DNA Replication in Eukaryotic Cells
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Nash, R.1
Lindahl, T.2
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0021919517
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Covalent modification of the recA protein from Escherichia coli with the photoaffinity label 8-azidoadenosine 5′-triphosphate
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Knight KL, McEntee K. Covalent modification of the recA protein from Escherichia coli with the photoaffinity label 8-azidoadenosine 5′-triphosphate. J Biol Chem. 260:1985;867-872.
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Knight, K.L.1
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