Regulation of the mitotic exit protein kinases CDc15 and Dbf2

Molecular Biology of the Cell

Volumn 12, Issue 10, 2001, Pages 2961-2974

  Visintin, R ^a   Amon, A ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN CDC14; PROTEIN CDC15; PROTEIN DBF2; RAS PROTEIN; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CELL CYCLE; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; ENZYME REGULATION; METAPHASE; MITOSIS; MITOSIS SPINDLE; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TELOPHASE; YEAST;

EID: 0035163233     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.10.2961     Document Type: Article

References (53)

1. Localization of core spindle pole body (SPB) components during SPB duplication in Saccharomyces cerevisiae
2. Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage
3. A novel functional domain of Cdc15 kinase is required for its interaction with the Tem1 GTPase in Saccharomyces cerevisiae
4. Tying the knot: Linking cytokinesis to the nuclear cycle
5. A mechanism for coupling exit from mitosis to partitioning of the nucleus
6. Anaphase spindle position is monitored by the BUB2 checkpoint
7. The budding yeast Cdc15 localizes to the spindle pole body in a cell-cycle-dependent manner
8. The polo-related kinase Cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae
9. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
10. Pds1p of budding yeast has dual roles: Inhibition of anaphase initiation and regulation of mitotic exit
11. The spindle checkpoint of Saccharomyces cerevisiae responds to separable microtubule-dependent events
12. P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae
13. Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1
14. A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast
15. Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2
16. The budding yeast dbf2 protein kinase localizes to the centrosome and moves to the bud neck in late mitosis
17. Nud1p links astral microtubule organization and the control of exit from mitosis
18. The protein kinases of budding yeast: Six score and more
19. A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae
20. Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14
21. Cdc14 activates cdc15 to promote mitotic exit in budding yeast
22. A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant dbf4 encodes a protein kinase and is identified as. CDC5
23. DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein
24. Regulation of A.P.C. activity by phosphorylation and regulatory factors
25. Mitotic regulation of the APC activator proteins CDC20 and CDH1
26. Bifurcation of the mitotic checkpoint pathway in budding yeast
27. Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis
28. MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy
29. Asymmetric spindle pole localization of yeast Cdc15 kinase links mitotic exit and cytokinesis
30. Regulation of the APC and the exit from mitosis
31. The Bub2p spindle checkpoint links nuclear migration with mitotic exit
32. Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiae
33. Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
34. The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase
35. Isolation of a Cdc25 family gene, MSI2/LTE1, as a multicopy suppressor of ira1
36. The polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae
37. APC-Cdc20 promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5
38. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
39. Sid2p, a spindle pole body kinase that regulates the onset of cytokinesis
40. Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
41. Destruction of the CDC28/CLB kinase is not required for metaphase/anaphase transition in yeast
42. Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage
43. The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition
44. Characterization of the Net1 cell cycle-dependent regulator of the Cdc14 phosphatase from budding yeast
45. CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
46. The phosphatase Cdc14 triggers mitotic exit by reversal of CDK-dependent phosphorylation
47. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
48. Movement of cortical actin patches in yeast
49. The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit
50. Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast
51. Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint
52. Progression into and out of mitosis
53. Whose end is destruction: Cell division and the anaphase-promoting complex