Intrahepatic mRNA levels of interferon γ and tumor necrosis factor α and response to antiviral treatment of chronic hepatitis C

Journal of Human Virology

Volumn 4, Issue 4, 2001, Pages 195-199

  Dumoulin, F L ^a   Wennrich, U ^a   Nischalke, H D ^a   Leifeld, L ^a   Fischer, H P ^a   Sauerbruch, T ^a   Spengler, U ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Antiviral therapy; Hepatitis C; IFN ; Intrahepatic cytokines; mRNA; Polymerase chain reaction; TNF

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS AGENT; CYTOKINE; GAMMA INTERFERON; MESSENGER RNA; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT ALPHA2B INTERFERON; RIBAVIRIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CLINICAL TRIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; LIVER BIOPSY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; VIRUS HEPATITIS;

ADOLESCENT; ADULT; AGED; ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; INTERFERON ALFA-2A; INTERFERON ALFA-2B; INTERFERON TYPE II; LIVER; MIDDLE AGED; RIBAVIRIN; RNA, MESSENGER; RNA, VIRAL; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA; VIRAL LOAD;

EID: 0035159049     PISSN: 10909508     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Molecular virology of the hepatitis C virus
2. Treatment of naive patients with chronic hepatitis C
3. Possible mechanisms of action and reasons for failure of antiviral therapy in chronic hepatitis C
4. Early predictors of response to treatment in patients with chronic hepatitis C
5. The non-structural 5A protein of hepatitis C virus
6. Intrahepatic hepatitis C virus-specific cytotoxic T lymphocyte activity and response to interferon alfa therapy in chronic hepatitis C
7. Hepatitis C virusspecific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C
8. Viral clearance without destruction of infected cells during acute HBV infection
9. Semiquantitative analysis of intrahepatic cytokine mRNAs in chronic hepatitis C
10. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
11. Definition of response to antiviral therapy in chronic hepatitis C
12. Quantitative PCR analysis of cytokine transcription patterns in peripheral mononuclear cells after anti-CD3 rejection therapy using two novel multispecific competitor fragments
13. Intrahepatic expression of interleukin-1beta and tumor necrosis factor-alpha in chronic hepatitis C
14. Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C
15. Hepatitis C virus core protein: Possible roles in viral pathogenesis
16. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein
17. Expression of hepatitis C virus proteins inhibits signal transduction through the Jak.STAT pathway
18. Soluble tumor necrosis factor receptors in chronic hepatitis C: A correlation with histological fibrosis and activity
19. Serum levels of soluble tumor necrosis factor receptors and effects of interferon therapy in patients with chronic hepatitis C virus infection