SCOPUS 정보 검색 플랫폼

Volumn 29, Issue 2, 2001, Pages 159-165

Application of rat hepatocyte culture to predict in vivo metabolic auto-induction: Studies with DFP, a cyclooxygenase-2 inhibitor

(9) Nicoll Griffith, Deborah A a Silva, Jose M a Chauret, Nathalie a Day, Stephen a Leblanc, Yves a Roy, Patrick a Yergey, James A a Dixit, Rakesh b Patrick, Darryl b

a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH (Canada)

b MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450 3A; DEXAMETHASONE; DRUG METABOLITE; DYFLOS;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DEALKYLATION; DOSE RESPONSE; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INDUCTION; LIVER CELL CULTURE; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALKYLATION; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZENE DERIVATIVES; BIOTRANSFORMATION; CELL CULTURE TECHNIQUES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; ENZYME INDUCTION; FURANS; HEPATOCYTES; HYDROXYLATION; ISOENZYMES; LIVER; MALE; NADP; OXIDOREDUCTASES, N-DEMETHYLATING; PREDICTIVE VALUE OF TESTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0035154160 PISSN: 00909556 EISSN: None Source Type: Journal
DOI: None Document Type: Article

Times cited : (14)

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