Advances in protein microarray technology for protein expression and interaction profiling

Current Opinion in Drug Discovery and Development

Volumn 4, Issue 1, 2001, Pages 116-123

  Haab, B B ^a  

^a VAN ANDEL INSTITUTE   (United States)

Author keywords

Array detection; High throughput; Microarray; Multicolor fluorescence; Protein; Protein substrate

Indexed keywords

PROTEIN;

DNA MICROARRAY; DRUG MANUFACTURE; ELECTRONICS; FLUORESCENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; REVIEW; SCREENING;

ANIMALS; DRUG INTERACTIONS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BIOSYNTHESIS; PROTEINS; ROBOTICS;

EID: 0035151047     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (39)

1. DNA sequencing using capillary array electrophoresis
2. Tissue microarrays for high-throughput molecular profiling of tumor specimens
3. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
4. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
5. Multiplexed biochemical assays with biological chips
6. Protein arrays for gene expression and molecular interaction screening
7. Large-scale functional analysis using peptide or protein arrays
8. A post-genomic challenge: Learning to read patterns of protein synthesis
9. Yeast microarrays for genome wide parallel genetic and gene expression analysis
10. Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid
11. Spot synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support
12. Light-directed, spatially addressable parallel chemical synthesis
13. Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis
14. UPA, a universal protein array system for quantitative detection of protein-protein, protein-DNA, protein-RNA and protein-ligand interactions
15. Hybridization analyses of arrayed cDNA libraries
16. A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library
17. A human cDNA library for high-throughput protein expression screening
18. Antibody arrays for high-throughput screening of antibody-antigen interactions
19. High-throughput microarray-based enzyme-linked immunosorbent assay (ELISA)
20. Printing proteins as microarrays for high-throughput function determination
21. Protein microarrays for gene expression and antibody screening
22. A microarray enzyme-linked immunosorbent assay for autoimmune diagnostics
23. Masssensing, multianalyte microarray immunoassay with imaging detection
24. Protein microdeposition using a conventional ink-jet printer
25. An array immunosensor for simultaneous detection of clinical analytes
26. Array biosensor for simultaneous identification of bacterial, viral, and protein analytes
27. Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions
28. Patterning of functional antibodies and other proteins by photolithography of silane monolayers
29. DNA analysis and diagnostics on oligonucleotide microchips
30. Manual manufacturing of oligonucleotide, DNA, and protein microchips
31. Protein microchips: Use for immunoassay and enzymatic reactions
32. Preparation of DNA and protein microarrays on glass slides coated with an agarose film
33. Microminiaturized immunoassays using atomic force microscopy and compositionally patterned antigen arrays
34. Profiling of Amyloid B peptide variants using SELDI ProteinChip arrays
35. Simultaneous synthesis of peptide libraries on single resin and continuous cellulose membrane supports: Examples for the identification of protein, metal and DNA binding peptide mixtures
36. Mapping protein-protein contact sites using cellulose-bound peptide scans
37. Searching for peptide ligands with an epitope library
38. RNA-peptide fusions for the in vitro selection of peptides and proteins