Retinoic acid selectively inhibits lipopolysaccharide induction of tissue factor gene expression in human monocytes

Blood

Volumn 91, Issue 8, 1998, Pages 2857-2865

  Oeth, Paul ^a   Yao, Jin ^a   Fan, Sao Tah ^a   Mackman, Nigel ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; RETINOIC ACID; THROMBOPLASTIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR CLONING; MONOCYTE; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

EID: 0032522969     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.8.2857.2857_2857_2865     Document Type: Article

References (56)

1. Bach RR: Initiation of coagulation by tissue factor. Crit Rev Biochem 23:339, 1988
2. Edgington TS, Mackman N, Brand K, Ruf W: The structural biology of expression and function of tissue factor. Thromb Haemost 66:67, 1991
3. Wilcox JN, Smith KM, Schwartz SM, Gordon D: Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 86:2839, 1989
4. Weinberg JB, Pippen AMM, Greenberg CS: Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum 34:996, 1991
5. Osterud B, Flæstad T: Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection: Related to an unfavorable prognosis. Thromb Haemost 49:5, 1983
6. Dorvak HF: Thrombosis and cancer. Hum Pathol 18:275, 1987
7. Barstad RM, Hamers MJAG, Stephens RW, Sakariassen KS: Retinoic acid reduces induction of monocyte tissue factor and tissue factor/factor VIIa-dependent arterial thrombus formation. Blood 86: 212, 1995
8. Falanga A, Consonni R, Marchetti M, Mielicki WP, Rambaldi A, Lanotte M, Gordon SG, Barbui T: Cancer procoagulant in the human promyelocytic cell line NB4 and its modulation by all-trans-retinoic acid. Leukemia 8:156, 1994
9. Koyama T, Hirosawa S, Kawamata N, Tohda S, Aoki N: All-trans retinoic acid upregulates thrombomodulin and downregulates tissue-factor expression in acute promyelocytic leukemia cells: Distinct expression of thrombomodulin and tissue factor in human leukemic cells. Blood 84:3001, 1994
10. Falanga A, Iacoviello L, Evangelista V, Belotti D, Consonni R, D'Orazio A, Robba L, Donati MB, Barbui T: Loss of blast cell procoagulant activity and improvement of hemostatic variables in patients with acute promyelocytic leukemia administered all-trans-retinoic acid. Blood 86:1072, 1995
11. Conese M, Montemurro P, Fumarulo R, Giordano D, Riccardi S, Colucci M, Semeraro N: Inhibitory effect of retinoids on the generation of procoagulant activity by blood mononuclear phagocytes. Thromb Haemost 66:662, 1991
12. Ishii H, Horie S, Kizaki K, Kazama M: Retinoic acid counteracts both the downregulation of thrombomodulin and the induction of tissue factor in cultured human endothelial cells exposed to tumor necrosis factor. Blood 80:2556, 1992
13. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schütz G, Umesono K, Blumberg B, Kastner P, Mark M, Chambon P, Evans RM: The nuclear receptor superfamily: The second decade. Cell 83:835, 1995
14. Consonni R, Falanga A, Barbui T: PML/RARα-dependence of tissue factor (TF) regulation by retinoids in promyelocytic leukemia cells: Comparison with normal human monocytes and U937 cells. Thromb Haemost 78:802, 1997
15. Mangelsdorf DJ, Evans RM: The RXR heterodimers and orphan receptors. Cell 83:841, 1995
16. Schule R, Rangarajan P, Yang N, Kliewer S, Ransone LJ, Bolado J, Verma IM, Evans RM: Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci USA 88:6092, 1991
17. Müller JM, Ziegler-Heitbrock HWL, Baeuerle PA: Nuclear factor kappa B, a mediator of lipopolysaccharide effects. Immunobiology 187:233, 1993
18. Trede NS, Tsytsykova AV, Chatila T, Goldfeld AE, Geha RS: Transcriptional activation of the human TNF-α promoter by superantigen in human monocytic cells: Role of NF-κB. J Immunol 902, 1995
19. Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, Akira S: Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc Natl Acad Sci USA 90:10193, 1993
20. Zhang Y, Broser M, Rom WN: Activation of the interleukin 6 gene by mycobacterium tuberculosis or lipopolysaccharide is mediated by nuclear factors NF-IL6. Proc Natl Acad Sci USA 91:2225, 1994
21. Kunsch C, Lang RK, Rosen CA, Shannon MF: Synergistic transcriptional activation of the IL-8 gene by NF-κB p65 (RelA) and NF-IL-6. J Immunol 153:153, 1994
22. Mackman N, Brand K, Edgington TS: Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor κB binding sites. J Exp Med 174:1517, 1991
23. Oeth P, Parry GCN, Mackman N: Regulation of the tissue factor gene in human monocytic cells. Role of AP-1, NF-κB/Rel and Sp1 proteins in uninduced and lipopolysaccharide-induced expression. Arterioscler Thromb Vasc Biol 17:365, 1997
24. Oeth PA, Parry GCN, Kunsch C, Nantermet P, Rosen CA, Mackman N: Lipopolysaccharide induction of tissue factor gene expression in monocytic cells is mediated by binding of c-Rel/p65 heterodimers to a κB-like site. Mol Cell Biol 14:3772, 1994
25. Mackman N: Protease inhibitors block lipopolysaccharide induction of tissue factor gene expression in human monocytic cells by preventing activation of c-Rel/p65 heterodimers. J Biol Chem 269: 26363, 1994
26. Osnes LTN, Foss KB, Joo GB, Okkenhaug C, Westvik A-B, Ovstebo R, Kierulf P: Acetylsalicylic acid and sodium salicylate inhibit LPS-induced NF-κB/c-Rel nuclear translocation, and synthesis of tissue factor (TF) and tumor necrosis factor alfa (TNF-α) in human monocytes. Thromb Haemost 76:970, 1996
27. Oeth P, Mackman N: Salicylates inhibit lipopolysaccharide induced transcriptional activation of the human tissue factor gene in monocytic cells. Blood 86:4144, 1995
28. Ollivier V, Parry GCN, Cobb RR, de Prost D, Mackman N: Elevated cyclic AMP inhibits NF-κB-mediated transcription in human monocytic cells and endothelial cells. J Biol Chem 271:20828, 1996
29. Parry GCN, Mackman N: Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-κB-mediated transcription. J Immunol 159:1997
30. Zhang WJ, Wojta J, Binder BR: Notoginsenoside R1 counteracts endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo. Arterioscler Thromb Vasc Biol 17:465, 1997
31. Nicholson RC, Mader S, Nagpal S, Leid M, Rochette-Egly C, Chambon P: Negative regulation of the rat stromalysin gene promoter by retinoic acid is mediated by an AP1 binding site. EMBO J 9:4443, 1990
32. Schroen DJ, Brinckerhoff CE: Inhibition of rabbit collagenase (matrix metalloproteinase-1; MMP-1) transcription by retinoid receptors: Evidence for binding of RARs/RXRs to the -77 AP-1 site through interactions with c-Jun. J Cell Physiol 169:320, 1996
33. Gille J, Paxton LLL, Lawley TJ, Caughman SW, Swelick RA: Retinoic acid inhibits the regulated expression of vascular cell adhesion molecule-1 by cultured dermal microvascular endothelial cells. J Clin Invest 99:492, 1997
34. Muller J, Brude RG, Buerki H, Keller HU, Hess MW, Cottier H: Non-specific acid phosphatase esterase activity: A criterion for differentiation of T and B lymphocytes in mouse lymphnodes. Eur J Immunol 5:270, 1975
35. Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T: Establishment and characterization of a human acute monocytic leukemia cell line (THP-1). Int J Cancer 26:171, 1980
36. Morrissey JH, Fair DS, Edgington TS: Monoclonal antibody analysis of purified and cell-associated tissue factor. Thromb Res 52:247, 1988
37. Virca GD, Northemann W, Shiels BR, Widera G, Broome S: Simplified Northern blot hybridization using 5% sodium dodecyl sulfate. Biotechniques 8:370, 1990
38. Morrissey JH, Fakhrai H, Edgington TS: Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade. Cell 50:129, 1987
39. Gregory SA, Morrissey JH, Edgington TS: Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin. Mol Cell Biol 9:2752, 1989
40. Brand K, Fowler BJ, Edgington TS, Mackman N: Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccharide. Mol Cell Biol 11:4732, 1991
41. Brown DA, Kondo KL, Wong SW, Diamond DJ: Characterization of nuclear protein binding to the interferon-gamma promoter in quiescent and activated human T cells. Eur J Immunol 22:2419, 1992
42. Cordle SR, Donald R, Read MA, Hawiger JJ: Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-κB proteins in human monocytic THP-1 cells. J Biol Chem 268:11803, 1993
43. Yao J, Mackman N, Edgington TS, Fan S-T: Lipopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells: Regulation by Egr-1, c-Jun and NF-κB transcription factors. J Biol Chem 272:17795, 1997
44. Karin M: The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483, 1995
45. Gross V, Villiger PM, Zhang B, Lotz M: Retinoic acid inhibits interleukin-1-induced cytokine synthesis in human monocytes. J Leukoc Biol 54:125, 1993
46. Stein B, Baldwin ASJ: Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB. Mol Cell Biol 13:7191, 1993
47. Bannister AJ, Oehler T, Wilhelm D, Angel P, Kouzarides T: Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene 11:2509, 1995
48. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin S-C, Heyman RA, Rose DW, Glass CK, Rosenfeld MG: A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403, 1996
49. Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ: Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 275:523, 1997
50. Gerritsen ME, Williams AJ, Neish AS, Moore S, Shi Y, Collins T: CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci USA 94:2927, 1997
51. Chen JD, Evans RM: A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377:454, 1995
52. Hörlein AJ, Näär AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, Ryan A, Kamei Y, Söderström M, Glass CK, Rosenfeld MG: Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377:397, 1995
53. Heinzel T, Lavinsky RM, Mullen T-M, Söderström M, Laherty CD, Torchia J, Yang W-M, Brard G, Ngo SD, Davie JR, Seto E, Eisenman RN, Rose DW, Glass CK, Rosenfeld MG: A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387:43, 1997
54. Alland L, Muhle R, Hou H, Jr., Potes J, Chin L, Schreiber-Agus N, DePinho RA: Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387:49, 1997
55. Beato M, Candau R, Chávez S, Möws C, Truss M: Interaction of steroid hormone receptors with transcription factors involves chromatin remodelling. J Steroid Biochem Mol Biol 56:47, 1996
56. 3-stimulated transcription. J Biol Chem 271: 20650, 1996