Virologic and immunologic effect of antiretroviral therapy on HIV-1 in gut-associated lymphoid tissue

Journal of Acquired Immune Deficiency Syndromes

Volumn 26, Issue 1, 2001, Pages 1-7

  Talal, Andrew H ^a,c   Monard, Simon ^a   Vesanen, Mika ^a   Zheng, Zhaoyao ^a   Hurley, Arlene ^a   Cao, Yunzhen ^a   Fang, Fang ^a   Smiley, Lynn ^b   Johnson, Judy ^b   Kost, Rhonda ^a   Markowitz, Martin H ^a  

^a AARON DIAMOND AIDS RESEARCH CENTER   (United States)

^b GLAXOSMITHKLINE   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Gut associated lymphoid tissue; Highly active antiretroviral therapy; Intestinal mucosa

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; LAMIVUDINE; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

ADULT; ARTICLE; CLINICAL ARTICLE; ENDOSCOPIC BIOPSY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNE RESPONSE; INTESTINE LYMPHATIC TISSUE; INTESTINE MUCOSA; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; RNA SPLICING; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; VIRUS INHIBITION;

EID: 0035144630     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-200101010-00001     Document Type: Article

References (39)

1. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatient study
2. + lymphocytes in HIV-1 infection
3. Viral dynamics in human immunodeficiency virus type 1 infection
4. HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
5. Decay characteristics of HIV-1-infected compartments during combination therapy
6. Quantitative image analysis of HIV-1 infection in lymphoid tissue
7. Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection
8. Evaluation of cell-free and cell-associated peripheral blood human immunodeficiency virus type-1 RNA response to antiretroviral therapy
9. Effect of combination antiretroviral therapy upon rectal mucosal HIV RNA burden and mononuclear cell apoptosis
10. Gut associated lymphoid tissue: Antigen handling and T-lymphocyte responses
11. Characterisation of mucosal lymphoid aggregates in ulcerative colitis: Immune cell phenotype and TcR-γδ expression
12. Regional specialization in the mucosal immune system: What happens in the microenvironments
13. Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation
14. T cell differentiation antigens on lymphocytes in the human intestinal lamina propria
15. + memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals
16. + T cell depletion and viral replication in SIV infection
17. + lymphocytes in HIV infection
18. + lymphocytes is an early feature of HIV infection
19. Mucosal macrophage subsets of the gut in HIV: Decrease in antigen - Presenting cell phenotype
20. + T lymphocytes in patients infected with human immunodeficiency virus type-1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin diarrhea/wasting syndrome study group
21. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma
22. Advances in antiretroviral therapy and viral load monitoring
23. Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1
24. Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity
25. Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells
26. Clinical evaluation of branched DNA signal amplification for quantifying HIV type 1 in human plasma
27. Rapid and simple PCR assay for quantification of HIV-1 RNA in plasma: Application to acute retroviral infection
28. + lymphocytes
29. Stability in controlling viral replication identifies long-term nonprogressors as a distinct subgroup among human immunodeficiency virus type 1-infected persons
30. Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy
31. Persistence of HIV-1 transcription in peripheral blood mononuclear cells in patients receiving potent antiretroviral therapy
32. Use of real-time PCR and molecular beacons to detect virus replication in human immunodeficiency virus type 1-infected individuals on prolonged effective antiretroviral therapy
33. Cell-associated viral RNA expression during acute infection with HIV type 1
34. Differential responsiveness to CD3-Ti vs. CD2-dependent activation of human intestinal T lymphocytes
35. Activation and signaling status of human lamina propria T lymphocytes
36. Definition of lamina propria T cell responsive state. Enhance cytokine responsiveness of T cells stimulated through the CD2 pathway
37. Hypoproliferative human lamina propria T cells retain the capacity to secrete lymphokines when stimulated via the CD2/CD28 accessory pathway
38. Effect of HIV-1 infection on lymphocyte proliferation in gut associated lymphoid tissue
39. + T helper cells repopulate the intestine early following antiretroviral therapy of simian immunodeficiency virus-infected rhesus macaques but exhibit a decreased potential to produce interleukin-2