Modulation of P450 CYP3A4-dependent metabolism by P-glycoprotein: Implications for P450 phenotyping

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 2, 2001, Pages 351-358

  Baron, Jens M ^b   Goh, Lay Beng ^a   Yao, Denggao ^c   Wolf, C Roland ^a   Friedberg, Thomas ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; FLAVONE DERIVATIVE; GLYCOPROTEIN P; HYDROCORTISONE; KETOCONAZOLE; OXYGENASE; QUINIDINE; RECOMBINANT ENZYME; TESTOSTERONE; VERAPAMIL; ZOSUQUIDAR;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME SUBSTRATE; FEMALE; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIFUNGAL AGENTS; CARDIOTONIC AGENTS; CELL LINE; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; DIGOXIN; HUMANS; HYDROXYLATION; KETOCONAZOLE; MIXED FUNCTION OXYGENASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; P-GLYCOPROTEIN; PHENOTYPE; STEROID HYDROXYLASES; TRANSFECTION;

EID: 0035140874     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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