New approaches to phenotypic analysis in adult mice

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 1, 2001, Pages 27-35

  Hoit, Brian D ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiovascular phenotype; Electrophysiology; Genetic engineering; Pressure; Volumetry

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA FLOW; DOPPLER ECHOCARDIOGRAPHY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; GENETIC ENGINEERING; MANOMETER; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PLETHYSMOGRAPHY; PRIORITY JOURNAL; REVIEW;

EID: 0035140709     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1294     Document Type: Review

References (67)

1. Non-invasive, in utero imaging of mouse embryonic heart development with 40-MHz echocardiography
2. In vivo assessment of embryonic cardiovascular dimensions and function in day 10.5 to 14.5 mouse embryos
3. Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene
4. Application of radio-telemetry of cardiovascular measurementss in pharmacology and toxicology
5. Depressed heart rate variability and arterial baroreflex in conscious transgenic mice with overexpression of cardiac Gsα
6. A new method for measurement of blood pressure, heart rate, and activity in the mouse by radiotelemetry
7. Naturally occurring variation in inbred mouse strains: A mouse model of the athlete's heart
8. Cardiovascular indexes in the mouse at rest and with exercise: New tools to study models of cardiac disease
9. Phospholamban deficiency does not compromise exercise capacity
10. Contractile function and low-intensity exercise effects of old dystrophic (mdx) mice
11. Impaired aerobic capacity in hypercholesterolemic mice: Partial reversal by exercise training
12. Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction
13. Invasive hemodynamic studies in open and closed chest mice
14. Cardiorespiratory reflexes in mice
15. Cardiac-specific overexpression of calsequestrin results in left ventricular hypertrophy, depressed force-frequency relation and pulsus alternans in vivo
16. In vivo determination of left ventricular wall stress-shortening relationship in normal mice
17. Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse
18. MLP-deficient mice exhibit a disruption of cardiac cyto-architectural organization, dilated cardiomyopathy, and heart failure
19. Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy
20. Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice
21. Echocardiographic assessment of the mouse heart
22. Two-dimesional echocardiography with a 15 MHz transducer is a promising alternative for in vivo measurements of left ventricular mass in mice
23. Decompensation of pressure-overload hypertrophy in G alpha q- overexpressing mice
24. Long-term transverse aortic banding is associated with similar functional alterations in phospholamban knockout and wild-type mice
25. Noninvasive assessment and necropsy validation of changes in left ventricular mass in ascending aortic banded mice
26. Three-dimensional echocardiographic assessment of left ventricular wall motion abnormalities in mouse myocardial infarction
27. Quantitative evaluation of left ventricular function in a transgenic mouse model of dilated cardiomyopathy with 2-dimensional contrast echo cardiography
28. Echocardiographic determination of risk area size in a murine model of myocardial ischemia
29. Determination of right ventricular structure and function in normoxic and hypoxic mice: A transesophageal echocardiographic study
30. Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3
31. Echocardiographic assessment of cardiac function in conscious and anesthetized mice
32. The effect of avertin anesthesia on the echocardiographic assessment of left ventricular function
33. In vivo murine left ventricular pressure-volume relations by miniaturized conductance micromanometry
34. Transgenic mouse model of stunned myocardium
35. Age-related left ventricular function in the mouse; analysis based on in vivo pressure-volume relationships
36. Estimation of parallel conductance by dual-frequency conductance catheter in mice
37. Development of a multifrequency conductance catheter-based system to determine LV function in mice
38. Validation of a mouse conductance system to determine LV volume: Comparison to echocardiography and crystals
39. Myocardial contractile function in transgenic mice overexpressing adenylyl cyclase 8 as assessed by the end-systolic pressure-volume relation
40. Ventricular pressure and dimension measurements in mice
41. Developmental changes of cardiac function and mass assessed with MRI in neonatal; juvenile, and adult mice
42. Gated magnetic resonance imaging of normal and hypertrophied murine hearts
43. Cardiac MRI of the normal and hypertrophied mouse heart
44. Magnetic resonance microimaging for non-invasive quantification of myocardial function and mass in the mouse
45. Magnetic resonance imaging and invasive evaluation of development of heart failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha
46. Magnetic resonance imaging of coronary arteries and heart valves in a living mouse: Techniques and preliminary results
47. Magnetic resonance imaging of perfusion in the isolated rat heart using spin inversion of arterial water
48. Left ventricular torsion is equal in mice and humans
49. In vivo metabolic imaging of cardiac bioenergetics in transgenic mice
50. In vivo measurement of myocardial mass using nuclear magnetic resonance imaging
51. A non-invasive computerized tail-cuff system for measuring blood pressure in mice
52. Cardiovascular effects of nociceptin in unanesthetized mice
53. Invasive hemodynamics and force-frequency relationships in open versus closed-chest mice
54. Influence of sarcoplasmic reticulum calcium loading on mechanical and relaxation restitution
55. Influence of transgenic overexpression of phospholamban on postextrasystolic potentiation
56. Modulation of the force-frequency relation by phospholamban in genetically engineered mice
57. Ryanodine and the left ventricular force interval and relaxation - Interval relations in closedchest dogs: Insights on calcium handling
58. Molecular and physiological alterations in murine ventricular dysfunction
59. Microsphere and dilution techniques for the determination of blood flows and volumes in conscious mice
60. Mechanisms, diagnosis, and treatment of diastolic heart failure
61. Rescue of high expression beta-tropomyosin transgenic mice by PTU: Regulating the alpha-myosin heavy chain promoter
62. Influence of loading conditions and contractile state on pulmonary venous flow. Validation of Doppler velocimetry
63. New Doppler echocardiographic applications for the study of diastolic function
64. Echocardiographic assessment of LV diastolic function in genetically altered mice
65. In vivo electrophysiologic studies in mice
66. Cardiac electrophysiology in generically engineered mice
67. Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype