Interpretation of X chromosome dose at Sex-lethal requires non-E-box sites for the basic helix-loop-helix proteins SISB and daughterless

Molecular and Cellular Biology

Volumn 21, Issue 5, 2001, Pages 1581-1592

  Yang, D ^a   Lu, H ^a   Hong, Y ^a   Jinks, T M ^a   Estes, P A ^a   Erickson, J W ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN;

ANIMAL CELL; ARTICLE; DROSOPHILA MELANOGASTER; LETHALITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; X CHROMOSOME;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA-GALACTOSIDASE; BINDING SITES; CELLS, CULTURED; CONSERVED SEQUENCE; DEOXYRIBONUCLEASE I; DNA FOOTPRINTING; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; FEMALE; GENE DELETION; HELIX-LOOP-HELIX MOTIFS; MALE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RNA-BINDING PROTEINS; SEX DETERMINATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSGENES; X CHROMOSOME;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0035137174     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.5.1581-1592.2001     Document Type: Article

References (53)

1. A natural classification of the basic helix-loop-helix class of transcription factors
2. Positional dependence, cliques, and predictive motifs in the bHLH protein domain
3. Genetic and molecular analysis of the autosomal component of the primary sex determination signal of Drosophila melanogaster
4. Binding of myc proteins to canonical and noncanonical DNA sequences
5. Sequence-specific DNA binding by the c-Myc protein
6. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection
7. Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo
8. Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila
9. Long-range repression in the Drosophila embryo
10. The enhanceosome and transcriptional synergy
11. Conservation of the Drosophila lateral inhibition pathway in human lung cancer: A hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression
12. The Drosophila sex determination signal: How do flies count to two?
13. Evidence that sisterless-a and sisterless-b are two of several discrete "numerator elements" of the X/A sex determination signal in Drosophila that switch Sxl between two alternative stable expression states
14. Vive la difference: Males vs females in flies vs worms
15. The daughterless gene product in Drosophila is a nuclear protein that is broadly expressed throughout the organism during development
16. Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins
17. scute (sis-b) function in Drosophila sex determination
18. A bZIP protein, SISTERLESS-A, collaborates with bHLH transcription factors early in Drosophila development to determine sex
19. Key aspects of the primary sex determination mechanism are conserved across the genus Drosophila
20. Molecular nature of the Drosophila sex determination signal and its link to neurogenesis
21. Multiple response elements in the Sex-lethal early promoter ensure its female-specific expression pattern
22. Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation
23. Interactions between dorsal and helix-loop-helix proteins initiate the differentiation of the embryonic mesoderm and neuroectoderm in Drosophila
24. Myc target genes
25. Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo
26. Higher-order nucleoprotein complexes in transcription: Analogies with site-specific recombination
27. Synergistic activation and repression of transcription by Drosophila homeobox proteins
28. Transcriptional regulation of the Sex-lethal gene by helix-loop-helix proteins
29. The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo
30. dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo
31. Functional gene cassettes in development
32. HLH proteins, fly neurogenesis, and vertebrate myogenesis
33. Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen
34. The JAK/STAT signalling pathway is required for the initial choice of sexual identity in Drosophila melanogaster
35. The primary sex determination signal of Drosophila acts at the level of transcription
36. Direct activation of Sex-lethal transcription by the Drosophila runt protein
37. Regulation of the proneural gene achaete by helix-loop-helix proteins
38. Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms
39. Hairy functions as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation
40. The bipartite D. melanogaster twist promoter is reorganized in D. virilis
41. X:A ratio, the primary sex-determining signal in Drosophila, is transduced by helix-loop-helix proteins
42. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
43. Regulation of the gene Sex-lethal: A comparative analysis of Drosophila melanogaster and Drosophila subobscura
44. The dual role of hermaphrodite in the Drosophila sex determination regulatory hierarchy
45. An extracellular activator of the Drosophila JAK/STAT pathway is a sex-determination signal element
46. DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins
47. Multiple modes of dorsal-bHLH transcriptional synergy in the Drosophila embryo
48. Mechanisms of transcriptional synergism of eukaryotic genes. The interferon-beta paradigm
49. The scute (T4) gene acts as a numerator element of the X:A signal that determines the state of activity of Sex-lethal in Drosophila
50. Negative regulation of proneural gene activity: Hairy is a direct transcriptional repressor of achaete
51. Lineage-specific regulation of the neural differentiation gene MASH1
52. deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination