The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster

Molecular Cell

Volumn 5, Issue 3, 2000, Pages 581-587

  Jinks, Timothy M ^a   Polydorides, Alexandros D ^a   Calhoun, Gretchen ^a   Schedl, Paul ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; LIGAND; STAT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOSOME; DROSOPHILA MELANOGASTER; EMBRYO; FEMALE; GENDER IDENTITY; GENE ACTIVATION; GENE EXPRESSION SYSTEM; GENE SEQUENCE; MALE; NONHUMAN; POLYMERIZATION; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; X CHROMOSOME;

ANIMALIA; DROSOPHILA MELANOGASTER; JANUS; MELANOGASTER;

EID: 0033696680     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80451-7     Document Type: Article

References (26)

1. Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila
2. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
3. The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster
4. Vive la difference: Males vs females in flies vs worms
5. STATs and gene regulation
6. Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster
7. Multiple response elements in the Sex-lethal early promoter ensure its female-specific expression pattern
8. Localized requirements for gene activity in segmentation of Drosophila embryos: Analysis of armadillo, fused, giant and unpaired mutations in mosaic embryos
9. The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus
10. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects
11. Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway
12. Transcriptional regulation of the Sex-lethal gene by helix-loop-helix proteins
13. Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs
14. Autoregulation of the Stat3 gene through cooperation with a cAMP-responsive element-binding protein
15. The primary sex determination signal of Drosophila acts at the level of transcription
16. Direct activation of Sex-lethal transcription by the Drosophila runt protein
17. Stat1 depends on transcriptional synergy with Sp1
18. PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene
19. Regulation of the gene Sex-lethal: A comparative analysis of Drosophila melanogaster and Drosophila subobscura
20. Sex determination in Drosophila melanogaster: X-linked genes involved in the initial step of sex-linked lethal activation
21. Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3
22. Characterization of a Stat-like DNA binding activity in Drosophila melanogaster
23. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. Part III. Zygotic loci on the X-chromosome and fourth chromosome
24. Identification of a Stat gene that functions in Drosophila development