Nitrosative stress in primary glial cultures after induction of the inducible isoform of nitric oxide synthase (i-NOS)

Toxicology

Volumn 148, Issue 2-3, 2000, Pages 133-142

  Noack, Heiko ^a   Possel, Heiko ^a   Chatterjee, Shampa ^a   Keilhoff, Gerburg ^a   Wolf, Gerald ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Microglial; Nitric oxide synthase; Oxidation

Indexed keywords

GLUTATHIONE; ISOENZYME; NITRIC OXIDE SYNTHASE; PEROXYNITRITE;

ANIMAL CELL; ASTROCYTE; CELL CULTURE; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; MICROGLIA; MITOCHONDRION; NEWBORN; NITROSATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; INTERFERON TYPE II; L-LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDES; NEUROGLIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; NITROSATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 0034618110     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00204-3     Document Type: Conference Paper

References (24)

1. Baker M., Cerniglia G.J., Zaman A. Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples. Anal. Biochem. 190:1990;360-365.
2. Beckman J.S., Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am. J. Physiol. 271:1996;C1424-1437.
3. Bredt D.S., Snyder S.H. Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63:1994;175-195.
4. Brown G.C. Nitric oxide and mitochondrial respiration. Biochim. Biophys. Acta. 5(1411):1999;351-369.
5. Butler A.R., Rhodes P. Chemistry, analysis and biological roles of S-nitrosothiols. Anal. Biochem. 248:1997;1-9.
6. Chatterjee S, Noack H, Possel H, Keilhoff G, Wolf G, 1999. Glutathione levels in primary glial cultures: monochlorobimane provides evidence of cell type-specific distribution, Glia 27, 152-161.
7. Dringen R., Hamprecht B. Involvement of glutathione peroxidase and catalase in the disposal of exogenous hydrogen peroxide by primary astrocyte cultures. Brain Res. 759:1997;67-75.
8. Galea E., Feinstein D.L., Reis D.J. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. USA. 89:1992;10945-10949.
9. Galea E., Reis D.J., Feinstein D.L. Cloning and expression of inducible nitric oxide synthase from rat astrocytes. J. Neurosci. Res. 37:1994;406-414.
10. Hevel J.M., Marletta M.A. Nitric-oxide synthase assays. Methods Enzymol. 233:1994;250-258.
11. Hothersall J.S., Cunha F.Q., Neild G.H., Norohna-Dutra A.A. Induction of nitric oxide synthesis in J774 cells lowers intracellular glutathione: effect of modulated glutathione redox status on nitric oxide synthase induction. Biochem. J. 322:1997;477-481.
12. Klegeris A., McGeer P.L. Rat brain microglia and peritoneal macrophages show similar responses to respiratory burst stimulants. J. Neuroimmunol. 53:1994;83-90.
13. Kooy N.W., Royall J.A., Ischiropoulos H. Oxidation of 2′,7′-dichlorofluorescin by peroxynitrite. Free Rad. Res. 27:1997;245-254.
14. Noack H., Lindenau J., Rothe F., Asayama K., Wolf G. Differential expression of superoxide dismutase isoforms in neuronal and glial compartments in the course of excitotoxically mediated neurodegeneration: relation to oxidative and nitrergic stress. Glia. 23:1998;285-297.
15. Packer M.A., Porteous C.M., Murphy M.P. Superoxide production by mitochondria in the presence of nitric oxide forms peroxynitrite. Biochem. Mol. Biol. Int. 40:1996;527-534.
16. Possel H., Noack H., Augustin W., Keilhoff G., Wolf G. 2,7-Dihydrodichlorofluorescein diacetate as a fluorescent marker for peroxynitrite formation. FEBS Lett. 416:1997;175-178.
17. Schägger H., von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Analyt. Biochem. 166:1987;368-379.
18. Schousboe A. Primary cultures of astrocytes from mammalian brain as a tool in neurochemical research. Cell. Mol. Biol. 26:1980;505-513.
19. Spector R. Micronutrient homeostasis in mammalian brain and cerebrospinal fluid. J. Neurochem. 53:1989;1667-1674.
20. Stamler J.S. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell. 78:1994;931-936.
21. Szabo C., Salzman A.L. Endogenously produced peroxynitrite induces the oxidation of mitochondrial and nuclear proteins in immunostimulated macrophages. FEBS Lett. 409:1997;147-150.
22. Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: application to mammalian blood and other tissues. Anal. Biochem. 27:1969;502-522.
23. Wahlefeld A.W. UV-method with L-lactate and NAD. Bergmeyer H.U., Bergmeyer J., Graßl M. Methods of Enzymatic Analysis (Enzyme I, Oxidoreductases). 1983;126-133 Verlag-Chemie, Berlin, Germany.
24. Whiteman M., Halliwell B. Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants. Free Rad. Res. 25:1996;275-283.