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Volumn 52, Issue , 2001, Pages 161-184

Novel platelet inhibitors

Author keywords

Aspirin; GPIIb IIIa antagonists; Platelet aggregation; Thienopyridines

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; ARGINYLGLYCYLASPARTIC ACID; CILOSTAZOL; CLOPIDOGREL; FIBRINOGEN RECEPTOR; INTEGRIN; MONOCLONAL ANTIBODY; PHOSPHODIESTERASE INHIBITOR; PROSTAGLANDIN SYNTHASE; TICLOPIDINE;

EID: 0035120357     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.52.1.161     Document Type: Review
Times cited : (107)

References (132)
  • 5
    • 0020692503 scopus 로고
    • Studies with a murine monoclonal antibody that abolishes ristocetin-induced binding of von Willebrand factor to platelets: Additional evidence in support of GPIb as a platelet receptor for von Willebrand factor
    • (1983) Blood , vol.61 , pp. 99-110
    • Coller, B.S.1    Peerschke, E.I.2    Scudder, L.E.3    Sullivan, C.A.4
  • 12
  • 19
    • 0031916728 scopus 로고    scopus 로고
    • Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets
    • (1998) J. Biol. Chem. , vol.273 , pp. 2030-2034
    • Jin, J.1    Daniel, J.L.2    Kunapuli, S.P.3
  • 21
    • 0031973037 scopus 로고    scopus 로고
    • Glycoprotein VI is a major collagen receptor for platelet activation: It recognizes the platelet-activating quaternary structure of collagen, whereas CD36, glycoprotein IIb/IIIa, and von Willebrand factor do not
    • (1998) Blood , vol.91 , pp. 491-499
    • Kehrel, B.1    Wierwille, S.2    Clemetson, K.J.3
  • 31
    • 0023728920 scopus 로고
    • Receptors linked to inhibition of adenylate cyclase: Additional signaling mechanisms
    • (1988) FASEB J. , vol.2 , pp. 2686-2695
    • Limbird, L.E.1
  • 36
    • 0022385454 scopus 로고
    • The tetrapeptide analogue of the cell attachment site of fibronectin inhibits platelet aggregation and fibrinogen binding to activated platelets
    • (1985) J. Biol. Chem. , vol.260 , pp. 11891-11894
    • Gartner, T.K.1    Bennett, J.S.2
  • 45
    • 0025090942 scopus 로고
    • Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease
    • The RISC Group
    • (1990) Lancet , vol.336 , pp. 827-830
  • 46
    • 0023805341 scopus 로고
    • Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17187 cases of suspected myocardial infarction: ISIS-2
    • (1988) Lancet , vol.2 , pp. 349-360
  • 47
    • 0028120906 scopus 로고
    • Collaborative overview of randomized trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, stroke by prolonged antiplatelet therapy in various categories of patients
    • (1994) Br. Med. J. , vol.308 , pp. 81-106
  • 49
    • 0024406369 scopus 로고
    • Final report on the aspirin component of the ongoing physicians' health study
    • (1989) N. Engl. J. Med. , vol.321 , pp. 129-135
  • 52
    • 0028140168 scopus 로고
    • 2/prostaglandin endoperoxide receptor antagonist, versus aspirin as adjunct to thrombolysis in patients with acute myocardial infarction: The ridogrel versus aspirin patency trial (RAPT)
    • (1994) Circulation , vol.89 , pp. 588-595
  • 56
    • 0029009904 scopus 로고
    • Antiplatelet drugs. A comparative review
    • (1995) Drugs , vol.50 , pp. 7-28
    • Schror, K.1
  • 58
    • 0025345221 scopus 로고
    • Antiplatelet treatment with ticlopidine in unstable angina. A controlled multicenter clinical trial
    • The Studio della Ticlopidina nell'Angina Instabile Group
    • (1990) Circulation , vol.82 , pp. 17-26
    • Balsano, F.1    Rizzon, P.2    Violi, F.3
  • 60
    • 0029742679 scopus 로고    scopus 로고
    • The STIMS trial: The ticlopidine experience and its clinical applications. Swedish Ticlopidine Multicenter Study
    • (1996) Vasc. Med. , vol.1 , pp. 141-143
    • Janzon, L.1
  • 62
    • 0030658097 scopus 로고    scopus 로고
    • Effect of ticlopidine on the long-term patency of saphenous-vein bypass grafts in the legs
    • Étude de la Ticlopidine après Pontage Femoro-Poplite and the Association Universitaire de Recherche en Chirurgie
    • (1997) N. Engl. J. Med. , vol.337 , pp. 1726-1731
    • Becquemin, J.P.1
  • 64
    • 0032481092 scopus 로고    scopus 로고
    • A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1665-1671
    • Leon, M.B.1    Baim, D.S.2    Popma, J.J.3
  • 65
    • 0031018569 scopus 로고    scopus 로고
    • Results of a consecutive series of patients receiving only antiplatelet therapy after optimized stent implantation. Comparison of aspirin alone versus combined ticlopidine and aspirin therapy
    • (1997) Circulation , vol.95 , pp. 1145-1156
    • Albiero, R.1    Hall, P.2    Itoh, A.3
  • 68
    • 0033518847 scopus 로고    scopus 로고
    • Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting. EPISTENT Investigators. Evaluation of Platelet IIb/IIIa Inhibitor for Stenting
    • (1999) JAMA , vol.281 , pp. 806-810
    • Steinhubl, S.R.1    Tan, W.A.2    Foody, J.M.3    Topol, E.J.4
  • 71
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 73
    • 0033545889 scopus 로고    scopus 로고
    • Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation
    • (1999) Circulation , vol.99 , pp. 2364-2366
    • Moussa, I.1    Oetgen, M.2    Roubin, G.3
  • 94
    • 0021965983 scopus 로고
    • A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb-IIIa complex
    • (1985) J. Clin. Invest. , vol.76 , pp. 101-108
    • Coller, B.S.1
  • 95
    • 0032748716 scopus 로고    scopus 로고
    • Binding of abciximab to αVβ3 and activated αMβ2 receptors: With a review of platelet-leukocyte interactions
    • (1999) Thromb. Haemostasis , vol.82 , pp. 326-336
    • Coller, B.S.1
  • 96
    • 0028117857 scopus 로고
    • Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty
    • (1994) Circulation , vol.90 , pp. 1757-1764
    • Tcheng, J.1    Ellis, S.2    George, B.3
  • 97
    • 0023838863 scopus 로고
    • Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparation
    • (1988) Circulation , vol.77 , pp. 670-677
    • Gold, H.K.1    Coller, B.S.2    Yasuda, T.3
  • 98
    • 0033529148 scopus 로고    scopus 로고
    • Differences among the parenteral platelet glycoprotein IIb/IIIa inhibitors and implications for treatment
    • (1999) Am. J. Cardiol. , vol.83
    • Tcheng, J.E.1
  • 99
    • 0032485876 scopus 로고    scopus 로고
    • Pharmacodynamic profile of short-term abciximab treatment demonstrates prolonged platelet inhibition with gradual recovery from GP IIb/IIIa receptor blockade
    • (1998) Circulation , vol.97 , pp. 1680-1688
    • Mascelli, M.A.1    Lance, E.T.2    Damaraju, L.3
  • 100
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
    • (1994) N. Engl. J. Med. , vol.330 , pp. 956-961
  • 101
    • 0030918995 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: The CAPTURE Study
    • (1997) Lancet , vol.349 , pp. 1429-1435
  • 102
    • 0033609314 scopus 로고    scopus 로고
    • Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels, c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) Study Investigators
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1623-1629
    • Hamm, C.W.1    Heeschen, C.2    Goldmann, B.3
  • 103
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization. The EPILOG Investigators
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1689-1696
  • 104
    • 0032508297 scopus 로고    scopus 로고
    • Randomised placebo-controlled and balloonangioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade. The EPISTENT Investigators. Evaluation of platelet IIb/IIIa inhibitor for stenting
    • (1998) Lancet , vol.352 , pp. 87-92
  • 105
    • 0033615009 scopus 로고    scopus 로고
    • Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of platelet IIb/IIIa inhibition in Stenting Investigators
    • (1999) N. Engl. J. Med. , vol.341 , pp. 319-327
    • Lincoff, A.M.1    Califf, R.M.2    Moliterno, D.J.3
  • 106
    • 0033547597 scopus 로고    scopus 로고
    • Outcomes at 1 year and economic implications of platelet glycoprotein IIb/IIIa blockade in patients undergoing coronary stenting: Results from a multicentre randomised trial. EPISTENT Investigators. Evaluation of platelet IIb/IIIa inhibitor for stenting
    • (1999) Lancet , vol.354 , pp. 2019-2024
    • Topol, E.J.1    Mark, D.B.2    Lincoff, A.M.3
  • 107
    • 0033613541 scopus 로고    scopus 로고
    • Optimizing the percutaneous interventional outcomes for patients with diabetes mellitus: Results of the EPISTENT (Evaluation of Platelet IIb/IIIa Inhibitor for Stenting Trial) diabetic substudy
    • (1999) Circulation , vol.100 , pp. 2477-2484
    • Marso, S.P.1    Lincoff, A.M.2    Ellis, S.G.3
  • 108
    • 0033951257 scopus 로고    scopus 로고
    • Potent complementary clinical benefit of abciximab and stenting during percutaneous coronary revascularization in patients with diabetes mellitus: Results of the EPISTENT trial
    • (2000) Am. Heart J. , vol.139
    • Lincoff, A.M.1
  • 110
    • 0032534461 scopus 로고    scopus 로고
    • Effect of glycoprotein IIb/IIIa receptor blockade on recovery of coronary flow and left ventricular function after the placement of coronary-artery stents in acute myocardial infarction
    • (1998) Circulation , vol.98 , pp. 2695-2701
    • Neumann, F.J.1    Blasini, R.2    Schmitt, C.3
  • 113
    • 0033566348 scopus 로고    scopus 로고
    • Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa
    • (1999) Blood , vol.94 , pp. 587-599
    • Bednar, B.1    Cook, J.J.2    Holahan, M.A.3
  • 117
    • 0030610564 scopus 로고    scopus 로고
    • 2+ on GP IIb-IIIa interactions with integrilin: Enhanced GP IIb-IIIa binding and inhibition of platelet aggregation by reductions in the concentration of ionized calcium in plasma anticoagulated with citrate
    • (1997) Circulation , vol.96 , pp. 1488-1494
    • Phillips, D.R.1    Teng, W.2    Arfsten, A.3
  • 118
    • 0030749074 scopus 로고    scopus 로고
    • Design and methodology of the PURSUIT trial: Evaluating eptifibatide for acute ischemic coronary syndromes. Platelet glycoprotein IIb-IIIa in unstable angina: Receptor suppression using integrilin therapy
    • (1997) Am. J. Cardiol. , vol.80
    • Harrington, R.A.1
  • 119
    • 0030919511 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Integrilin to minimise platelet aggregation and coronary thrombosis-II
    • (1997) Lancet , vol.349 , pp. 1422-1428
  • 120
    • 0006099476 scopus 로고    scopus 로고
    • Deleted in proof
  • 123
    • 0343376106 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty. The RESTORE Investigators. Randomized Efficacy Study of Tirofiban for Outcomes and REstenosis
    • (1997) Circulation , vol.96 , pp. 1445-1453
  • 124
    • 0001859684 scopus 로고    scopus 로고
    • Six-month angiographic and clinical follow-up of patients prospectively randomized to receive either tirofiban or placebo during angioplasty in the RESTORE trial. Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 28-34
    • Gibson, C.M.1    Goel, M.2    Cohen, D.J.3
  • 125
    • 2642654221 scopus 로고    scopus 로고
    • A comparison of aspirin plus tirofiban with aspirin plus heparin for unstable angina
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1498-1505
  • 126
    • 0033589739 scopus 로고    scopus 로고
    • Troponin concentrations for stratification of patients with acute coronary syndromes in relation to therapeutic efficacy of tirofiban. PRISM Study Investigators. Platelet receptor inhibition in ischemic syndrome management
    • (1999) Lancet , vol.354 , pp. 1757-1762
    • Heeschen, C.1    Hamm, C.W.2    Goldmann, B.3
  • 127
    • 2642599026 scopus 로고    scopus 로고
    • Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1488-1497
  • 128
    • 0031808541 scopus 로고    scopus 로고
    • Oral inhibitors of platelet membrane receptor glycoprotein IIb/IIIa in clinical cardiology: Issues and opportunities
    • (1998) Am. Heart J. , vol.135
    • Theroux, P.1
  • 130
    • 0034728088 scopus 로고    scopus 로고
    • Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomized trial
    • (2000) Lancet , vol.355 , pp. 337-345
  • 132
    • 0033542929 scopus 로고    scopus 로고
    • Meeting highlights. Highlights of the 48th scientific sessions of the American College of Cardiology
    • (1999) Circulation , vol.100 , pp. 570-575
    • Ferguson, J.J.1


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