p16(INK4a), but not constitutively active pRb, can impose a sustained G1 arrest: Molecular mechanisms and implications for oncogenesis

Oncogene

Volumn 18, Issue 27, 1999, Pages 3930-3935

  Lukas, Jiri ^a   Sørensen, Claus S ^a   Lukas, Claudia ^a   Santoni Rugiu, Eric ^a   Bartek, Jiri ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Cyclin D CDK4(6); Cyclin E CDK2; G1 phase arrest; Oncogenesis; p16 CDK inhibitor; Retinoblastoma protein

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN E; PROTEIN P16; PROTEIN P21; RETINOBLASTOMA PROTEIN; CDK2 PROTEIN, HUMAN; CDK2 PROTEIN, RAT; CYCLIN DEPENDENT KINASE 2; GROWTH INHIBITOR; PROTEIN P16INK4A; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIVISION; COMPLEX FORMATION; CONTROLLED STUDY; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NONHUMAN; PHENOTYPE; PLOIDY; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL TRANSFORMATION; COMPARATIVE STUDY; GENETICS; METABOLISM; OSTEOSARCOMA; PHYSIOLOGY;

ANIMALS; CDC2-CDC28 KINASES; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; G1 PHASE; GENE TRANSFER TECHNIQUES; GROWTH INHIBITORS; HUMANS; OSTEOSARCOMA; PROTEIN-SERINE-THREONINE KINASES; RATS; RETINOBLASTOMA PROTEIN; S PHASE; TUMOR CELLS, CULTURED;

EID: 0033536076     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202777     Document Type: Article

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