Significance of IgE-binding epitopes in allergic disease

Journal of Allergy and Clinical Immunology

Volumn 107, Issue 2, 2001, Pages 219-221

  Bufe, Albrecht ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Allergen processing; Allergen structure; Cow's milk allergy; IgE; IgE binding epitopes; Pollen allergens

Indexed keywords

ALLERGEN; EPITOPE; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; POLLEN ANTIGEN;

ALLERGIC DISEASE; EDITORIAL; FOOD ALLERGY; GRASS POLLEN; HUMAN; MILK; MILK ALLERGY; POLLEN ALLERGY; PRIORITY JOURNAL;

EID: 0035113510     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2001.112850     Document Type: Article

References (26)

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3. Epitope mapping of allergens and antigens of timothy grass pollen extract
4. The use of multiple-pin peptide synthesis in an analysis of the continuous epitopes recognised by various anti-(recombinant bovine growth hormone) sera
5. IgE epitopes on the cat (Felis domesticus) major allergen Fel d I: A study with overlapping synthetic peptides
6. Major allergen Ph1 p Va (timothy grass) bears at least two different IgE-reactive epitopes
7. Isolation of an immunodominant IgE hapten from an epitope expression cDNA library
8. Mapping of the antigenic and allergenic epitopes of Lo1p Vb using gene fragmentation
9. Mapping of IgE binding epitopes on the recombinant major group I allergen of velvet grass pollen, rHo1 1 1
10. Mapping and mutational analysis of the IgE-binding epitopes on Ara h 1, a legume vicilin protein and a major allergen in peanut hypersensitivity
11. Molecular basis of IgE-recognition of Lo1 p 5, a major allergen of rye-grass pollen
12. "Allergen engineering": Variants of the timothy grass pollen allergen Ph1 p 5b with reduced IgE-binding capacity but conserved T cell reactivity
13. Conformational stability of B cell epitopes on group I and group II Dermatophagoides ssp. allergens
14. Conversion of the major birch pollen allergen Bet v 1, into two nonanaphylactic T cell epitope-containing fragments
15. Reduction in IgE binding to allergen variants generated by site-directed mutagenesis: Contribution of disulphide bonds to antigenic structure of the major house dust mite allergen Der p2
16. Engineering of the house dust mite allergen Der f 2 for allergen-specific immunotherapy
17. X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy
18. Discontinuous IgE-binding epitopes contain multiple continuous epitope regions: Results of an epitope mapping on Hol 1 5, a major allergen from velvet grass pollen
19. Dominant epitopes and allergic cross-reactivity: Complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1
20. Complementary, specificity and the nature of epitopes and paratopes in multivalent interactions
21. Allergenic activity of a major pollen allergen is elevated in the presence of nasal secretion
22. Crystal structure of the human high-affinity IgE receptor
23. Hydrodynamic studies of a complex between the Fc fragment of human IgE and a soluble fragment of the FcεRIα-chain
24. Long-lasting sensitization to food during the first two years precedes allergic airway disease
25. Characterization of Ara h 1 by two-dimensional electrophoresis immunoblot and recombinant techniques: New digestion experiments with peanuts imitating the gastrointestinal tract
26. Induction of antibody responses to new B cell epitopes indicates vaccination character of allergen immunotherapy