메뉴 건너뛰기




Volumn 29, Issue 6, 1999, Pages 2026-2036

Induction of antibody responses to new B cell epitopes indicates vaccination character of allergen immunotherapy

Author keywords

Allergy; Antibody; Epitope; Immunotherapy; Vaccine

Indexed keywords

ALLERGEN; EPITOPE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G4; POLLEN ANTIGEN;

EID: 0033065121     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199906)29:06<2026::AID-IMMU2026>3.0.CO;2-2     Document Type: Article
Times cited : (137)

References (54)
  • 6
    • 0031736285 scopus 로고    scopus 로고
    • Allergen immunotherapy: Therapeutic vaccines for allergic diseases. A WHO position paper
    • Bousquet, J., Lockey, R., Malling, H. J. and the WHO panel members, Allergen immunotherapy: Therapeutic vaccines for allergic diseases. A WHO position paper. J. Allergy Clin. Immunol. 1998. 102: 558-562.
    • (1998) J. Allergy Clin. Immunol. , vol.102 , pp. 558-562
    • Bousquet, J.1    Lockey, R.2    Malling, H.J.3
  • 7
    • 50249230114 scopus 로고
    • Prophylactic inoculation against hayfever
    • Noon, L., Prophylactic inoculation against hayfever. Lancet 1911. 1: 1572-1573.
    • (1911) Lancet , vol.1 , pp. 1572-1573
    • Noon, L.1
  • 8
    • 0031784380 scopus 로고    scopus 로고
    • Immunological changes associated with allergen immunotherapy
    • Durham, S. R. and Till, S. J., Immunological changes associated with allergen immunotherapy. J. Allergy Clin. Immunol. 1998. 102: 157-164.
    • (1998) J. Allergy Clin. Immunol. , vol.102 , pp. 157-164
    • Durham, S.R.1    Till, S.J.2
  • 9
    • 34247569209 scopus 로고
    • Serological evidence on immunity with co-existing sensitization in a type of human allergy, hay fever
    • Cooke, R., Barnard, J., Hebald, S. and Stull, A., Serological evidence on immunity with co-existing sensitization in a type of human allergy, hay fever. J. Exp. Med. 1935. 62: 733-750.
    • (1935) J. Exp. Med. , vol.62 , pp. 733-750
    • Cooke, R.1    Barnard, J.2    Hebald, S.3    Stull, A.4
  • 10
    • 0002866703 scopus 로고
    • Immunological studies of pollinosis: I. The presence of two antibodies related to the same pollen antigen in the serum of treated hay fever patients
    • Loveless, M. H., Immunological studies of pollinosis: I. The presence of two antibodies related to the same pollen antigen in the serum of treated hay fever patients. J. Immunol. 1940. 38: 25-50.
    • (1940) J. Immunol. , vol.38 , pp. 25-50
    • Loveless, M.H.1
  • 11
    • 0000669090 scopus 로고
    • Immunological studies on pollinosis. IV. The relationship between thermostable antibody in the circulation and clinical immunity
    • Loveless, M. H., Immunological studies on pollinosis. IV. The relationship between thermostable antibody in the circulation and clinical immunity. J. Immunol. 1943. 47: 165-180.
    • (1943) J. Immunol. , vol.47 , pp. 165-180
    • Loveless, M.H.1
  • 12
    • 0014319420 scopus 로고
    • A quantitative in vitro study of the chromatographic distribution and immunoglobulin characteristics of human blocking antibody
    • Lichtenstein, L. M., Holtzman, N. A. and Burnett, L. S., A quantitative in vitro study of the chromatographic distribution and immunoglobulin characteristics of human blocking antibody. J. Immunol. 1968. 101: 317-324.
    • (1968) J. Immunol. , vol.101 , pp. 317-324
    • Lichtenstein, L.M.1    Holtzman, N.A.2    Burnett, L.S.3
  • 13
    • 0017143720 scopus 로고    scopus 로고
    • Measurement of IgG blocking antibodies: Development and application of a radioimmunoassay
    • Sobotka, A. K., Valentine, M. D., Ishizaka, K. and Lichtenstein, L. M., Measurement of IgG blocking antibodies: development and application of a radioimmunoassay. J. Immunol. 1996. 117: 84-90.
    • (1996) J. Immunol. , vol.117 , pp. 84-90
    • Sobotka, A.K.1    Valentine, M.D.2    Ishizaka, K.3    Lichtenstein, L.M.4
  • 14
    • 0018395666 scopus 로고
    • Evaluation of the quantity and affinity of human IgG "blocking" antibodies
    • Adkinson, N. F., Sobotka, A. K. and Lichtenstein, L. M., Evaluation of the quantity and affinity of human IgG "blocking" antibodies. J. Immunol. 1979. 122: 965-972.
    • (1979) J. Immunol. , vol.122 , pp. 965-972
    • Adkinson, N.F.1    Sobotka, A.K.2    Lichtenstein, L.M.3
  • 15
    • 0019491586 scopus 로고
    • Measurement of IgG blocking antibodies by interference in the radioallergosorbent test
    • Gleich, G. J., Zimmermann, E. M., Gleich, M. C. and Yunginger, J. W., Measurement of IgG blocking antibodies by interference in the radioallergosorbent test. J. Immunol. 1981. 126: 575-579.
    • (1981) J. Immunol. , vol.126 , pp. 575-579
    • Gleich, G.J.1    Zimmermann, E.M.2    Gleich, M.C.3    Yunginger, J.W.4
  • 16
    • 0020700160 scopus 로고
    • Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response
    • Aalberse, R. C., Gaag, R. and Leeuwen, J., Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response. J. Immunol. 1983. 130: 722-726.
    • (1983) J. Immunol. , vol.130 , pp. 722-726
    • Aalberse, R.C.1    Gaag, R.2    Leeuwen, J.3
  • 17
    • 0019998115 scopus 로고
    • Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: A six-year prospective study
    • Gleich, G. J., Zimmermann, E. M., Henderson, L. L. and Yunginger, J. W., Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six-year prospective study. J. Allergy Clin. Immunol. 1982. 70: 261-271.
    • (1982) J. Allergy Clin. Immunol. , vol.70 , pp. 261-271
    • Gleich, G.J.1    Zimmermann, E.M.2    Henderson, L.L.3    Yunginger, J.W.4
  • 18
    • 0022455948 scopus 로고
    • Subclass of IgG anti-bee venom antibody produced during bee venom immunotherapy and its relationship to long-term protection from bee stings and following termination of venom immunotherapy
    • Urbanek, R., Kemeny, D. M. and Richards, D., Subclass of IgG anti-bee venom antibody produced during bee venom immunotherapy and its relationship to long-term protection from bee stings and following termination of venom immunotherapy. Clin. Allergy 1986. 16: 317-322.
    • (1986) Clin. Allergy , vol.16 , pp. 317-322
    • Urbanek, R.1    Kemeny, D.M.2    Richards, D.3
  • 19
    • 0025179309 scopus 로고
    • Evaluation of immunotherapy-induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting. Correlation with clinical response
    • Birkner, T., Rumpold, H., Jarolim, E., Ebner, H., Breitenbach, M., Skvaril, T., Scheiner, O. and Kraft, D., Evaluation of immunotherapy-induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting. Correlation with clinical response. Allergy 1990. 41: 418-426.
    • (1990) Allergy , vol.41 , pp. 418-426
    • Birkner, T.1    Rumpold, H.2    Jarolim, E.3    Ebner, H.4    Breitenbach, M.5    Skvaril, T.6    Scheiner, O.7    Kraft, D.8
  • 20
    • 0021131157 scopus 로고
    • IgG subclass antibody response in grass pollen-allergic patients undergoing specific immunotherapy. Prognostic value of serum IgG subclass antibody levels in immunotherapy
    • Djurup, R. and Osterballe, O., IgG subclass antibody response in grass pollen-allergic patients undergoing specific immunotherapy. Prognostic value of serum IgG subclass antibody levels in immunotherapy. Allergy 1984. 39: 433-441.
    • (1984) Allergy , vol.39 , pp. 433-441
    • Djurup, R.1    Osterballe, O.2
  • 23
    • 0030003889 scopus 로고    scopus 로고
    • Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-γ
    • Durham, S. R., Ying, S., Varney, V. A., Jacobson, M. R., Sudderick, R. M., Mackay, I. S., Kay, A. B. and Hamid, Q. A., Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-γ. J. Allergy Clin. Immunol. 1996. 97: 1356-65.
    • (1996) J. Allergy Clin. Immunol. , vol.97 , pp. 1356-1365
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3    Jacobson, M.R.4    Sudderick, R.M.5    Mackay, I.S.6    Kay, A.B.7    Hamid, Q.A.8
  • 25
    • 0023722274 scopus 로고
    • The effect of immunotherapy on bronchial hyper-responsiveness and eosinophil cationic protein in pollen allergic patients
    • Rak, S., Rowhagen, O. and Venge, P., The effect of immunotherapy on bronchial hyper-responsiveness and eosinophil cationic protein in pollen allergic patients. J. Allergy Clin. Immunol. 1988. 82: 470-480.
    • (1988) J. Allergy Clin. Immunol. , vol.82 , pp. 470-480
    • Rak, S.1    Rowhagen, O.2    Venge, P.3
  • 26
    • 0018875627 scopus 로고
    • Generation of antigen-specific supressor cells during allergy desensitization
    • Rocklin, R. E., Sheffer, A., Greineder, D. K. and Melmon, K. L., Generation of antigen-specific supressor cells during allergy desensitization. N. Engl. J. Med. 1980. 302: 1213-1219.
    • (1980) N. Engl. J. Med. , vol.302 , pp. 1213-1219
    • Rocklin, R.E.1    Sheffer, A.2    Greineder, D.K.3    Melmon, K.L.4
  • 28
    • 0028931038 scopus 로고
    • Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type
    • Secrist, H., DeKruyff, R. H. and Umetsu, D. T., Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type. J. Exp. Med. 1995. 181: 1081-1089.
    • (1995) J. Exp. Med. , vol.181 , pp. 1081-1089
    • Secrist, H.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 29
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures
    • Jutel, M., Pichler, W. J., Skrbic, D., Urwyler, A., Dahinden, C. and Müller, U. R., Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures. J. Immunol. 1995. 154: 4187-4194.
    • (1995) J. Immunol. , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Müller, U.R.6
  • 30
    • 0031034644 scopus 로고    scopus 로고
    • House dust mite immunotherapy results in a decrease in der p 2-specific IFN-γ and IL-4 expression by circulation T lymphocytes
    • O'Brien, R. M., Byron, K. A., Varigos, G. A. and Thomas, W. R., House dust mite immunotherapy results in a decrease in Der p 2-specific IFN-γ and IL-4 expression by circulation T lymphocytes. Clin. Exp. Allergy 1997. 27: 46-51.
    • (1997) Clin. Exp. Allergy , vol.27 , pp. 46-51
    • O'Brien, R.M.1    Byron, K.A.2    Varigos, G.A.3    Thomas, W.R.4
  • 31
    • 15444353066 scopus 로고    scopus 로고
    • Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation
    • Vrtala, S., Ball, T., Spitzauer, S., Pandjaitan, B., Suphioglu, C., Knox, B., Sperr, W. R., Valent, P., Kran, D. and Valenta, R., Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation. J. Immunol. 1998. 160: 6137-6144.
    • (1998) J. Immunol. , vol.160 , pp. 6137-6144
    • Vrtala, S.1    Ball, T.2    Spitzauer, S.3    Pandjaitan, B.4    Suphioglu, C.5    Knox, B.6    Sperr, W.R.7    Valent, P.8    Kran, D.9    Valenta, R.10
  • 32
    • 0028032391 scopus 로고
    • Complementary DNA cloning of the major allergen Phl p 1 from timothy grass (Phleum pratense); recombinant Phl p 1 inhibits IgE binding to group I allergens from eight different grass species
    • Laffer, S., Valenta, R., Vrtala, S., Susani, M., van Ree, R., Kraft, D., Scheiner, O. and Ducnene, M., Complementary DNA cloning of the major allergen Phl p 1 from timothy grass (Phleum pratense); recombinant Phl p 1 inhibits IgE binding to group I allergens from eight different grass species. J. Allergy Clin. Immunol. 1994. 94: 689-698.
    • (1994) J. Allergy Clin. Immunol. , vol.94 , pp. 689-698
    • Laffer, S.1    Valenta, R.2    Vrtala, S.3    Susani, M.4    Van Ree, R.5    Kraft, D.6    Scheiner, O.7    Ducnene, M.8
  • 34
  • 35
    • 0025936007 scopus 로고
    • Antigen dose dependent regulation of B epsilon-memory cell expression
    • Kolbe, L., Heusser, C. and Kölsch, E., Antigen dose dependent regulation of B epsilon-memory cell expression. Int. Arch. Allergy Appl. Immunol. 1991. 95: 202-206.
    • (1991) Int. Arch. Allergy Appl. Immunol. , vol.95 , pp. 202-206
    • Kolbe, L.1    Heusser, C.2    Kölsch, E.3
  • 36
    • 0031881193 scopus 로고    scopus 로고
    • Differential regulation of human T cell cytokine patterns and IgE and IgG4 responses by conformational antigen variants
    • Akdis, C. A., Blesken, T., Wymann, D., Akdis, M. and Blaser, K., Differential regulation of human T cell cytokine patterns and IgE and IgG4 responses by conformational antigen variants. Eur. J. Immunol. 1998. 28: 914-925.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 914-925
    • Akdis, C.A.1    Blesken, T.2    Wymann, D.3    Akdis, M.4    Blaser, K.5
  • 37
    • 9844266243 scopus 로고    scopus 로고
    • Immunological changes during specific immunotherapy of grass pollen allergy: Reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen
    • Ebner, C., Siemann, U., Bohle, B., Wilhelm, M., Wiedermann, U., Schenk, S., Klotz, F., Ebner, H., Kraft, D. and Scheiner, O., Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen. Clin. Exp. Allergy 1997. 27: 1007-1015.
    • (1997) Clin. Exp. Allergy , vol.27 , pp. 1007-1015
    • Ebner, C.1    Siemann, U.2    Bohle, B.3    Wilhelm, M.4    Wiedermann, U.5    Schenk, S.6    Klotz, F.7    Ebner, H.8    Kraft, D.9    Scheiner, O.10
  • 38
    • 0029586091 scopus 로고
    • Recombinant allergens for diagnosis and therapy of allergic diseases
    • Valenta, R. and Kraft, D., Recombinant allergens for diagnosis and therapy of allergic diseases. Curr. Opin. Immunol. 1995. 7: 751-756.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 751-756
    • Valenta, R.1    Kraft, D.2
  • 41
    • 0027939421 scopus 로고
    • Isolation of an immunodominant IgE-hapten from an epitope expression cDNA library; dissection of the allergic effector reaction
    • Ball, T., Vrtala, S., Sperr, W. R., Valent, P., Susani, M., Kraft, D. and Valenta, R., Isolation of an immunodominant IgE-hapten from an epitope expression cDNA library; dissection of the allergic effector reaction. J. Biol. Chem. 1994. 269: 28323-28328.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28323-28328
    • Ball, T.1    Vrtala, S.2    Sperr, W.R.3    Valent, P.4    Susani, M.5    Kraft, D.6    Valenta, R.7
  • 42
    • 0029999352 scopus 로고    scopus 로고
    • Reduction in IgE binding to allergen variants generated by site-directed mutagenesis: Contribution of disulfide bonds to the antigenic structure of the major house dust mite allergen der p 2
    • Smith, A. M. and Chapman, M. D., Reduction in IgE binding to allergen variants generated by site-directed mutagenesis: contribution of disulfide bonds to the antigenic structure of the major house dust mite allergen Der p 2. Mol. Immunol. 1996. 33: 399-405.
    • (1996) Mol. Immunol. , vol.33 , pp. 399-405
    • Smith, A.M.1    Chapman, M.D.2
  • 44
    • 0030937231 scopus 로고    scopus 로고
    • Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments. Candidates for a novel form of specific immunotherapy
    • Vrtala, S., Hirtenlehner, K., Vangelista, L., Pastore, A., Eichler, H. G., Sperr, W. R., Valent, P., Ebner, C., Kraft, D. and Valenta, R., Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments. Candidates for a novel form of specific immunotherapy. J. Clin. Invest. 1997. 99: 1673-1681.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1673-1681
    • Vrtala, S.1    Hirtenlehner, K.2    Vangelista, L.3    Pastore, A.4    Eichler, H.G.5    Sperr, W.R.6    Valent, P.7    Ebner, C.8    Kraft, D.9    Valenta, R.10
  • 47
    • 0029870704 scopus 로고    scopus 로고
    • Immunologic characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p 2, Phl p 5)
    • Vrtala, S., Susani, M., Sperr, W. R., Valent, P., Laffer, S., Dolecek, C., Kraft, D. and Valenta, R., Immunologic characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p 2, Phl p 5). J. Allergy Clin. Immunol. 1996. 97: 781-787.
    • (1996) J. Allergy Clin. Immunol. , vol.97 , pp. 781-787
    • Vrtala, S.1    Susani, M.2    Sperr, W.R.3    Valent, P.4    Laffer, S.5    Dolecek, C.6    Kraft, D.7    Valenta, R.8
  • 49
    • 0028307758 scopus 로고
    • CDNA cloning and expression of timothy grass (Pleum pratense) pollen profilin in Escherichia coli: Comparison with birch pollen profilin
    • Valenta, R., Ball, T., Vrtala, S., Duchêne, M., Kraft, D. and Scheiner, O., cDNA cloning and expression of timothy grass (Pleum pratense) pollen profilin in Escherichia coli: comparison with birch pollen profilin. Biochem. Biophys. Res. Commun. 1994. 199: 106-118.
    • (1994) Biochem. Biophys. Res. Commun. , vol.199 , pp. 106-118
    • Valenta, R.1    Ball, T.2    Vrtala, S.3    Duchêne, M.4    Kraft, D.5    Scheiner, O.6
  • 50
    • 0030568856 scopus 로고    scopus 로고
    • High-level expression in Escherichia coli and purification of recombinant plant profilins: Comparison of IgE-binding capacity and allergenic activity
    • Vrtala, S., Wiedemann, P., Mittermann, I., Eichler, H. G., Sperr, W. R., Valent, P., Kraft, D. and Valenta, R., High-level expression in Escherichia coli and purification of recombinant plant profilins: Comparison of IgE-binding capacity and allergenic activity. Biochem. Biophys. Res. Commun. 1996. 226: 42-50.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 42-50
    • Vrtala, S.1    Wiedemann, P.2    Mittermann, I.3    Eichler, H.G.4    Sperr, W.R.5    Valent, P.6    Kraft, D.7    Valenta, R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.