'Allergen engineering': Variants of the timothy grass pollen allergen Phl p 5b with reduced IgE-binding capacity but conserved T cell reactivity

Journal of Immunology

Volumn 162, Issue 4, 1999, Pages 2406-2414

  Schramm, Gabriele ^a   Kahlert, Helga ^b   Suck, Roland ^b   Weber, Bernhard ^b   Stüwe, Hans Thomas ^b   Müller, Wolf Dieter ^c   Bufe, Albrecht ^a   Becker, Wolf Meinhard ^a   Schlaak, Max W ^a   Jäger, Lothar ^c   Cromwell, Oliver ^b   Fiebig, Helmut ^b  

^a RESEARCH CENTER BORSTEL   (Germany)

^b ALLERGOPHARMA JOACHIM GANZER KG   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE; MUTANT PROTEIN; POLLEN ANTIGEN;

ANTIGEN BINDING; ARTICLE; BASOPHIL; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DESENSITIZATION; DRUG POTENCY; EPITOPE MAPPING; GENETIC ENGINEERING; HISTAMINE RELEASE; HUMAN; HUMAN CELL; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; PRICK TEST; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; SUBCUTANEOUS DRUG ADMINISTRATION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; VACCINE PRODUCTION;

ALLERGENS; BINDING SITES, ANTIBODY; CELL LINE; CLONE CELLS; EPITOPE MAPPING; HISTAMINE RELEASE; HUMANS; IMMUNOGLOBULIN E; PLANT PROTEINS; POACEAE; POLLEN; PROTEIN ENGINEERING; SKIN TESTS; T-LYMPHOCYTES; VARIATION (GENETICS);

EID: 0033558133     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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