Functional polymorphism within the promotor of the serotonin transporter gene is associated with severe hyperkinetic disorders

Molecular Psychiatry

Volumn 6, Issue 2, 2001, Pages 235-238

  Seeger, G ^a   Schloss, P ^a   Schmidt, M H ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Conduct disorder; Hyperkinetic disorder; Serotonin transporter gene

Indexed keywords

DNA; FLUVOXAMINE; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; COMORBIDITY; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; HYPERKINESIA; MAJOR CLINICAL STUDY; MALE; NEUROTRANSMISSION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR GENE; SEROTONINERGIC SYSTEM; TREATMENT OUTCOME;

ADOLESCENT; CARRIER PROTEINS; CHILD; CONDUCT DISORDER; FEMALE; GENOTYPE; HUMANS; HYPERKINESIS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 0035112730     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000820     Document Type: Article

References (32)

1. The serotonin transporter: A primary target for antidepressant drugs
2. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
3. Comorbidity of attention-deficit/hyperactivity disorder with psychiatric disorder: An overview
4. Examination of DSM-IV criteria for attention deficit/hyperactivity disorder in a county-wide sample
5. The prevalence of attention deficit disorders in a rural midwestern community sample of nine-year-old children
6. Hyperkinetic disorders in seven-year-old children with perceptual, motor and attentional deficits
7. Impulsivity, aggression, and neuroendocrine responses to serotonergic stimulation in substance abusers
8. Blood platelet uptake of serotonin in episodic aggression
9. Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects
10. Isolation of a cDNA encoding the human brain serotonin transporter
11. Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization
12. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
13. Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder
14. Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
15. Treatment of ADHD with fluoxetine: A preliminary trial
16. Fluoxetine for ADHD in a young child
17. Open-label treatment of comorbid depression and attentional disorders with co-administration of serotonin reuptake inhibitors and psychostimulants in children, adolescents, and adults: A case series
18. A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia
19. 2 test: Implementation by means of StatXact 3 For Windows
20. Association of aggressive behavior with altered serotonergic functions in patients who are not suicidal
21. Central serotonin and impulsive aggression
22. Suicidal behavior, impulsiveness and serotonin
23. Attempted suicide characteristics and cerebrospinal fluid amine metabolites in depressed inpatients
24. Postmortem evidence for serotonin's role in suicide
25. Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder
26. Normative data on revised Conners parent and teacher rating scales
27. Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene
28. Allelic variation of human serotonin transporter gene expression
29. Organization of the human serotonin transporter gene