Apoptosis contributes to amphotericin B-induced nephrotoxicity

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 3, 2001, Pages 679-685

  Varlam, D E ^a   Siddiq, M M ^a   Parton, L A ^a   Russmann H ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; DNA FRAGMENT; SOMATOMEDIN C;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; DEHYDRATION; DOSE RESPONSE; HISTOPATHOLOGY; KIDNEY CONCENTRATING CAPACITY; KIDNEY DISTAL TUBULE; KIDNEY PROXIMAL TUBULE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT;

AMPHOTERICIN B; ANIMALS; ANTIBIOTICS, ANTIFUNGAL; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DOGS; DRUG INTERACTIONS; INSULIN-LIKE GROWTH FACTOR I; KIDNEY; MALE; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; SWINE;

EID: 0035111992     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.3.679-685.2001     Document Type: Article

References (42)

1. Acceleration of recovery in acute renal failure: From cellular mechanisms of tubular repair to innovative targeted therapies
2. Synthesis and binding of insulin-like growth factor 1 by human glomerular mesangial cells
3. Interactions between bcl-2 and the IGF system control apoptosis in the developing mouse brain
4. How do the polyene macrolide antibiotics affect the cellular membrane properties?
5. Amphotericin B: Current understanding of mechanism of action
6. Amphotericin B nephrotoxicity: Increased renal resistance and tubule permeability
7. In vitro tumor necrosis factor induction assay for analysis of febrile toxicity associated with amphotericin B preparations
8. Tissue concentration and bioactivity of amphotericin B in cancer patients treated with amphotericin B-deoxycholate
9. Synthesis and release of insulinlike growth factor 1 by mesangial cells in culture
10. Insulin-like growth factor-1 prevents caspase-mediated apoptosis in Schwann cells
11. Gentamicin-induced apoptosis in renal cell lines and embryonic fibroblasts
12. Cyclosporine induces different responses in human epithelial, endothelial and fibroblast cell cultures
13. Matrix accumulation in mesangial cells exposed to cyclosporine A requires a permissive genetic background
14. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
15. An experimental model of amphotericin B nephrotoxicity with renal tubular acidosis
16. Overview of the treatment of disseminated fungal infections
17. To die or not to die: An overview of apoptosis and its role in disease
18. Mechanisms of insulin growth factor-I-induced accelerated recovery in experimental acute renal failure
19. Interactions of free and liposomal amphotericin B with renal proximal tubular cells in primary culture
20. Amphotericin B- and folic acid-induced nephropathies in developing rats
21. Nephrotoxicity of amphotericin B in rats: Effects of the time of administration
22. Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury
23. Insulin-like growth factor-1 enhances epidermal growth factor receptor activation and renal tubular cell regeneration in postischemic acute renal failure
24. Insulin-like growth factor-1 ameliorates delayed kidney graft function and the acute nephrotoxic effecs of cyclosporine
25. Local and systemic host defense mechanism against Candida: Immunopathology of candidal infections
26. Insulin-like growth factor-1 inhibits mature oligodendrocytes apoptosis during primary demyelinisation
27. Rat models for clinical use of insulin-like growth factor 1 in acute renal failure
28. IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress
29. Hyperplasia, hypertrophy, and phenotypic alterations in the distal tubule after acute proximal injury in the rat
30. Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis
31. Cyclosporine A induces apoptosis in murine tubular epithelial cells: Role of caspases
32. Drug-induced nephropathies
33. Insulin-like growth factor I inhibition of apoptosis is associated with increased expression of the local bcl-xL gene product
34. Localization of mRNAs for insulin-like growth factor binding protein 1 to 6 in the rat kidney
35. Phosphatidylinositol 3-kinase mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-1
36. Apoptosis and the kidney
37. Expression of apoptosis regulatory genes in chronic cyclosporine A nephrotoxicity favors apoptosis
38. Mechanisms and genes of cellular suicide
39. Caspases: Enemies within
40. Renal ultrastructure after amphotericin B
41. Direct amphotericin B-mediated tubular toxicity: Assessments of selected cytoprotective agents
42. Pathogenetic mechanisms in nephrotoxic acute renal failure