Effects of a dual inhibitor of tumor necrosis factor-α and interleukin-1 on lipopolysaccharide-induced lung injury in rats: Involvement of the p38 mitogen-activated protein kinase pathway

Critical Care Medicine

Volumn 29, Issue 3, 2001, Pages 628-634

  Yoshinari, Daisuke ^a   Takeyoshi, Izumi ^a,c   Koibuchi, Yukio ^a   Matsumoto, Koshi ^b   Kawashima, Yoshiyuki ^a   Koyama, Toru ^a   Ohwada, Susumu ^a   Morishita, Yasuo ^a  

^a GUNMA UNIVERSITY   (Japan)

^b NIPPON MEDICAL SCHOOL MUSASHI KOSUGI HOSPITAL   (Japan)

^c NONE   (Japan)

Author keywords

FR167653; Interleukin 1; Kinase; Lipopolysaccharide; Lung; Mitogen activated protein kinase; P38; Rat; Tumor necrosis factor

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; INTERLEUKIN 2; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THROMBOXANE B2; TUMOR NECROSIS FACTOR ALPHA;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME PHOSPHORYLATION; HISTOPATHOLOGY; IMMUNOBLOTTING; LETHALITY; LUNG EDEMA; LUNG INJURY; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS;

EID: 0035100129     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200103000-00029     Document Type: Article

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