The use of biologic materials in spinal fusion

Orthopedics

Volumn 24, Issue 2, 2001, Pages 191-197

  Vaccaro, A R ^a   Sharan, A D ^a   Tuan, R S ^a   Kang, J D ^a   An, H S ^a   Morone, M A ^a   Savas, P E ^a   Hilibrand, A S ^a   Abitbol, J J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; BONE MORPHOGENETIC PROTEIN; DNA; GROWTH FACTOR;

ALLOGRAFT; BONE CONDUCTION; BONE GRAFT; BONE MATRIX; BONE PROSTHESIS; BONE TRANSPLANTATION; CORTICAL BONE; DEMINERALIZATION; FEMUR; FIBULA; GENE THERAPY; GENE TRANSFER; GENETIC ENGINEERING; HUMAN; HUMAN CELL; ILIAC CREST; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; MOLECULAR BIOLOGY; PATHOGENESIS; REVIEW; RIB; SPINE FUSION; SPINE STABILIZATION; SURGICAL TECHNIQUE; TARGET ORGAN;

ANIMALS; BONE MATRIX; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; BONE TRANSPLANTATION; COLLAGEN; GENE THERAPY; GROWTH SUBSTANCES; HUMANS; PROSTHESES AND IMPLANTS; SPINAL DISEASES; SPINAL FUSION; TRANSPLANTATION, AUTOLOGOUS;

EID: 0035095390     PISSN: 01477447     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (28)

1. Viral vectors for gene therapy
2. Transforming growth factor-beta regulates production of proteoglycans by mesangial cells
3. Recombinant human osteogenic protein 1 is a potent stimulator of the synthesis of cartilage proteoglycans and collagens by human articular chondrocytes
4. Stimulation of proteoglycan synthesis in explants of porcine articular cartilage by recombinant osteogenic protein-1 (bone morphogenetic protein-7)
5. Autocrine/paracrine mechanism of insulin-like growth factor-1 secretion, and the effect of insulin-like growth factor-1 on proteoglycan synthesis in bovine intervertebral discs
6. Altered epidermal cell growth control in vivo by inducible expression of transforming growth factor beta 1 in the skin of transgenic mice
7. Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: An in vivo study of adenovirus mediated transfer of the human transforming growth factor β1 encoding gene
8. Morbidity at bone graft donor sites
9. Bone: Formation by autoinduction
10. Gene expression during autograft lumbar spine fusion and the effect of bone morphogenetic protein 2
11. Augmentation of spinal fusion with bone morphogenetic protein in dogs
12. Lumbar intertransverse-process spinal arthrodesis with use of a bovine bone-derived osteoinductive protein. A preliminary report
13. Experimental spinal fusion with recombinant human bone morphogenetic protein-2
14. The safety of OP-1 for lumbar fusion with decompression-a canine study
15. Use of porous hydroxyapatite graft containing recombinant human bone morphogenetic protein-2 for cervical fusion in a caprine model
16. Osteogenic protein versus autologous interbody arthrodesis in the sheep thoracic spine. A comparative endoscopic study using the Bagby and Kuslich interbody fusion device
17. Reversing the inhibitory effect of nicotine on spinal fusion using an osteoinductive protein extract
18. Induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene in a rabbit spinal fusion model
19. The use of coralline hydroxyapatite with bone marrow, autogenous bone graft, or osteoinductive bone protein extract for posterolateral lumbar spine fusion
20. Replacement of the lumbar vertebrae of sheep with ceramic prostheses
21. Reactions of bone tissue in old rats to three different implant materials
22. Bridging large defects in bone by demineralized bone matrix in the form of a powder. A radiographic, histological, and radioisotope-uptake study in rats
23. New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis
24. In vivo evaluation of demineralized bone matrix as a bone graft substitute for posterior spinal fusion
25. Utilization of type I collagen gel, demineralized bone matrix, and bone morphogenetic protein-2 to enhance autologous bone lumbar spinal fusion
26. Use of autologous growth factors in lumbar spinal fusion
27. Simultaneous combined anterior and posterior lumbar fusion with femoral cortical allograft