Utilization of type I collagen gel, demineralized bone matrix, and bone morphogenetic protein-2 to enhance autologous bone lumbar spinal fusion

Journal of Neurosurgery

Volumn 86, Issue 1, 1997, Pages 93-100

  Helm, Gregory A ^a   Sheehan, Jonas M ^b   Sheehan, Jason P ^b   Jane Jr , John A ^b   Dipierro, Charles G ^b   Simmons, Nathan E ^b   Gillies, George T ^b   Kallmes, David F ^b   Sweeney, Thomas M ^b  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b NONE

Author keywords

bone morphogenetic protein; collagen; demineralized bone matrix; spinal fusion

Indexed keywords

BONE MORPHOGENETIC PROTEIN; COLLAGEN TYPE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRODESIS; ARTICLE; BIOMECHANICS; BONE GRAFT; BONE MASS; CONTROLLED STUDY; DEMINERALIZATION; DOG; ENCHONDRAL OSSIFICATION; LUMBAR SPINE; NONHUMAN; PRIORITY JOURNAL; SPINE FUSION; VOLUMETRY;

EID: 0031032276     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1997.86.1.0093     Document Type: Article

References (42)

1. Becker U, Timpl R, Kühn K: Carboxyterminal antigenic determinants of collagen from calf skin. Localization within discrete regions of the nonhelical sequence. Eur J Biochem 28: 221-231, 1972
2. Bolander ME, Balian G: The use of demineralized bone matrix in the repair of segmental defects. J Bone Joint Surg (Am) 68:1264-1274, 1986
3. Bowers G, Felton F, Middleton C, et al: Histologic comparison of regeneration in human intrabony defects when osteogenin is combined with demineralized freeze-dried bone allograft and with purified bovine collagen. J Periodontol 62:690-702, 1991
4. Celeste AJ, Iannazzi JA, Taylor RC, et al: Identification of transforming growth factor B family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87:9843-9847, 1990
5. Cook SD, Baffes GC, Wolfe MW, et al: Recombinant human bone morphogenetic protein-7 induces healing in a canine long-bone segmental defect model. Clin Orthop 301:302-312, 1994
6. Cook SD, Dalton JE, Tan EH, et al: In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusions. Spine 19:1655-1663, 1994
7. Davison PF, Levine L, Drake MP, et al: The serologic specificity of tropocollagen telepeptides. J Exp Med 126:331-346, 1967
8. Deporter DA, Komori N, Howley TP, et al: Reconstituted bovine skin collagen enhances healing of bone wounds in the rat calvaria. Calcif Tissue Int 42:321-325, 1987
9. DeVore DT: Collagen xenografts for bone replacement: the effects of aldehyde-induced cross-linking on degradation rate. Oral Surg Oral Med Oral Pathol 3:677-686, 1977
10. diPierro CG, Helm GA, Shaffrey CI, et al: Treatment of lumbar spinal stenosis by extensive unilateral decompression and contralateral autologous bone fusion: operative technique and results. J Neurosurg 84:166-173, 1996
11. Einhorn TA, Lane JM, Burstein AH, et al: The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study. J Bone Joint Surg (Am) 66:274-279, 1984
12. Frenkel SR, Moskovich R, Spivak J, et al: Demineralized bone matrix. Enhancement of spinal fusion. Spine 18:1634-1639, 1993
13. Gerhart TN, Kirker-Head CA, Kriz MJ, et al: Healing segmental femoral defects in sheep using recombinant human bone morphogenetic protein. Clin Orthop 293:317-326, 1993
14. Guizzardi S, DiSilvestre M, Scandroglio R, et al: Implants of heterologous demineralized bone matrix for induction of posterior spinal fusion in rats. Spine 17:701-707, 1992
15. Guterman IA, Boman TE, Wang GJ, et al: Bone induction in intramuscular implants by demineralized bone matrix: sequential changes of collagen synthesis. Collagen Rel Res 8: 419-431, 1988
16. Koenig BB, Cook JS, Wolsing DH, et al: Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Mol Cell Biol 14:5961-5974, 1994
17. Lindsley H, Mannik M, Bornstein P: The distribution of antigenic determinants in rat skin collagen. J Exp Med 133: 1309-1324, 1971
18. Lovell TP, Dawson EG, Nilsson OS, et al: Augmentation of spinal fusion with bone morphogenetic protein in dogs. Clin Orthop 243:266-274, 1989
19. Muschler GF, Lane JM, Dawson EG: The biology of spinal fusion, in Cotler DC, Cotler HB (eds): Spinal Fusion. Science and Technique. New York: Springer-Verlag, 1990, pp 9-21
20. Paralkar VM, Nandedkar AKN, Pointer RH, et al: Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen. J Biol Chem 265:17281-17284, 1990
21. Pfeilschifter J, Wolf O, Naumann A, et al: Chemotactic response of osteoblastlike cells to transforming growth factor β. J Bone Miner Res 5:825-830, 1990
22. Ragni PC, Lindholm TS: Bone formation and static changes in the thoracic spine at uni-or bilateral experimental spondylodesis with demineralized bone matrix (DBM). Ital J Orthop Traumatol 15:237-252, 1989
23. Sampath TK, Muthukumaran N, Reddi AH: Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography. Proc Natl Acad Sci USA 84:7109-7113, 1987
24. Sasano Y, Ohtani E, Narita K, et al: BMPs induce direct bone formation in ectopic sites independent of the endochondral ossification in vivo. Anat Rec 236:373-380, 1993
25. Schimandle JH, Boden SD, Hutton WC: Experimental spinal fusion with recombinant human bone morphogenetic protein-2. Spine 20:1326-1337, 1996
26. Schmitt FO, Levine L, Drake MP, et al: The antigenicity of tropocollagen. Proc Natl Acad Sci USA 51:493-497, 1964
27. Sheehan JP, Kalmes DF, Sheehan JM, et al: Molecular methods of enhancing lumbar spine fusion. Neurosurgery 39:1-8, 1996
28. Steffen C, Timpl R, Wolff I: Immunogenicity and specificity of collagen. V. Demonstration of three different antigenic determinants on calf collagen. Immunology 15:135-144, 1968
29. Summers BN, Eisenstein SM: Donor site pain from the ilium. A complication of lumbar spine fusion. J Bone Joint Surg (Br) 71:677-680, 1989
30. Sweeney TM, Opperman LA, Persing JA, et al: Repair of critical size rat calvarial defects using extracellular matrix protein gels. J Neurosurg 83:710-715, 1995
31. Toriumi DM, Kotler HS, Luxenberg DP, et al: Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation. Arch Otolaryngol Head Neck Surg 117:1101-1112, 1991
32. Urist MR: Bone: formation by autoinduction. Science 150: 893-899, 1965
33. Urist MR, Huo YK, Brownell AG, et al: Purification of bovine bone morphogenetic protein by hydroxylapatite chromatography. Proc Natl Acad Sci USA 86:371-375, 1984
34. Urist MR, Mikulski A, Lietze A: Solubilized and insolubilized bone morphogenetic protein. Proc Natl Acad Sci USA 76: 1828-1832, 1979
35. Vukicevic S, Paralkar VM, Cunningham NS, et al: Autoradiographic localization of osteogenin binding sites in cartilage and bone during rat embryonic development. Dev Biol 140: 209-214, 1990
36. Wang EA, Rosen V, D'Alessandro JS, et al: Recombinant human bone morphogenetic protein induces bone formation. Proc Natl Acad Sci USA 87:2220-2224, 1990
37. Ward JW: Femoral head transmits AIDS. Am Assoc Tissue Banks Newsletter 11:1, 1988
38. Wozney JM: The bone morphogenetic protein family and osteogenesis. Mol Reprod Dev 32:160-167, 1992
39. Wozney JM, Rosen V, Celeste AJ, et al: Novel regulators of bone formation: molecular clones and activities. Science 242: 1528-1534, 1988
40. Yamaji N, Celeste AJ, Thies RS, et al: A mammalian serine-threonine kinase receptor specifically binds BMP-2 and BMP-4. Biochem Biophys Res Commun 205:1944-1951, 1994
41. Yasko AW, Lane JM, Fellinger EJ, et al: The healing of segmental bone defects, induced by rcombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. J Bone Joint Surg (Am) 74: 659-671, 1992
42. Younger EM, Chapman MW: Morbidity at the bone graft donor sites. J Orthop Trauma 3:192-195, 1989