Antimicrobial proteins and peptides in host defense

Seminars in Respiratory Infections

Volumn 16, Issue 1, 2001, Pages 4-10

  Ganz, Tomas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN; DEFENSIN; HISTATIN; LACTOFERRIN; LYSOZYME; MAGAININ 1; PHOSPHOLIPASE A2; PROTEGRIN; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

ANTIGEN SPECIFICITY; ANTIMICROBIAL ACTIVITY; BACTERIAL COLONIZATION; BACTERIAL FLORA; BRONCHUS SECRETION; COMPLEMENT ACTIVATION; ENZYME INHIBITION; HOST RESISTANCE; HUMAN; INFLAMMATORY CELL; MUCOCILIARY CLEARANCE; PEPTIDE ANALYSIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN TRANSPORT; REVIEW;

EID: 0035069470     PISSN: 08820546     EISSN: None     Source Type: Journal    
DOI: 10.1053/srin.2001.22723     Document Type: Review

References (41)

1. On a remarkable bacteriolytic element found in tissues and secretions
2. Innate antimicrobial activity of nasal secretions
3. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
4. Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
5. The genesis of cystic fibrosis lung disease
6. Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface
7. Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections
8. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
9. Human nasal respiratory secretions and host defense
10. Human nasal host defense and sinusitis
11. Bactericidal activity of human lysozyme, muramidase-inactive lysozyme, and cationic polypeptides against Streptococcus sanguis and Streptococcus faecalis: Inhibition by chitin oligosaccharides
12. Killing of gram-negative bacteria by lactoferrin and lysozyme
13. Bactericidal activity of human lactoferrin: Differentiation from the stasis of iron deprivation
14. Iron and infection
15. The effects of lactoferrin on gram-negative bacteria
16. A helical region on human lactoferrin. Its role in antibacterial pathogenesis
17. Lactoferricin, a new antimicrobial peptide
18. Distribution of secretory leukoprotease inhibitor in the human nasal airway
19. Antibacterial activity of antileukoprotease
20. Antimicrobial peptides of phagocytes and epithelia
21. Determinants of the inhibitory action of purified 14-kDa phospholipases A2 on cell-free prothrombinase complex
22. Defensins
23. hBD-1: A novel beta-defensin from human plasma
24. Human beta-defensin-1: An antimicrobial peptide of urogenital tissues
25. A peptide antibiotic from human skin
26. Production of β-defensins by human airway epithelia
27. Structure, function, and membrane integration of defensins
28. Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
29. The role of protegrins and other elastase-activated polypeptides in the bactericidal properties of porcine inflammatory fluids
30. Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins
31. Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins
32. FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis
33. The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes
34. Human CAP18: A novel antimicrobial lipopolysaccharide-binding protein
35. hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules
36. The human antibacterial cathelicidin, hCAP-18, is synthesized in myelocytes and metamyelocytes and localized to specific granules in neutrophils
37. Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins
38. The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders
39. Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli
40. Protegrin-1: A broad-spectrum, rapidly microbicidal peptide with in vivo activity
41. Preliminary evaluation of recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in children with severe meningococcal sepsis