Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase A - Dependent mechanism

GLIA

Volumn 33, Issue 4, 2001, Pages 324-333

  Cho, Sunghee ^a   Kim, Yoonseong ^a   Cruz, Manuel O ^a   Park, Eun Mi ^a   Chu, Chung K ^b   Song, Gyu Yong ^b   Joh, Tong H ^a  

^a BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

BV 2 microglia cells; cAMP; N acetyl O methyldopamine (NAMDA); NF B mediated gene transcription; pCREB

Indexed keywords

ADENOSINE 3',5' PHOSPHOROTHIOATE; CELL STIMULATION; CYTOKINE; DEGENERATIVE DISEASE; DNA BINDING; GENE EXPRESSION; GENE REPRESSION; GENETIC REGULATION; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; MICROGLIA; N ACETYL O METHYLDOPAMINE; NERVE CELL; NITRIC OXIDE SYNTHASE; PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMALS; CELL LINE, TRANSFORMED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GTP CYCLOHYDROLASE; INTERLEUKIN-1; MICROGLIA; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035068235     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-1136(20010315)33:4<324::AID-GLIA1031>3.0.CO;2-M     Document Type: Article

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