Topiramate in trigeminal neuralgia: A randomized, placebo-controlled multiple crossover pilot study

Clinical Neuropharmacology

Volumn 24, Issue 2, 2001, Pages 109-112

  Gilron, Ian ^a   Booher, Susan L ^b   Rowan, Janet S ^b   Max, Mitchell B ^a,b  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Crossover studies; Facial neuralgia; Pain; Placebo; Topiramate; Trigeminal neuralgia

Indexed keywords

TOPIRAMATE;

ADULT; ARTICLE; CASE REPORT; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE ASSOCIATION; DISEASE DURATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; MALE; PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; TREATMENT PLANNING; TRIGEMINUS NEURALGIA;

ADULT; AGED; ANTICONVULSANTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; FRUCTOSE; HUMANS; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PAIN MEASUREMENT; PILOT PROJECTS; PLACEBOS; TRIGEMINAL NEURALGIA;

EID: 0035066925     PISSN: 03625664     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002826-200103000-00009     Document Type: Article

References (11)

1. Long-term treatment of trigeminal neuralgia with carbamazepine
2. Trigeminal, eye and ear pain
3. AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans
4. Effects of the AMPA/kainate antagonist LY293558 on spontaneous and evoked postoperative pain
5. Topiramate selectively blocks kainate currents in cultured hippocampal-neurons
6. Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells
7. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold
8. Topiramate relieves refractory intercostal neuralgia
9. Potential role of topiramate in relief of neuropathic pain
10. Ratio scales of sensory and affective verbal pain descriptors
11. Transdermal clonidine compared to placebo in painful diabetic neuropathy using a two-stage 'enriched enrollment' design