BMPs: Actions in flesh and bone

Nature Medicine

Volumn 3, Issue 8, 1997, Pages 837-839

  Reddi, A Hari ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN;

BONE; BONE GROWTH; HUMAN; MOLECULAR BIOLOGY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIVISION; HUMANS; MORPHOGENESIS; SIGNAL TRANSDUCTION;

EID: 0030813959     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0897-837     Document Type: Short Survey

References (12)

1. Nusslein-Vollhard, C. & Wieschaus, E. Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801 (1980).
2. Urist, M.R. Bone: Formation by autoinduction. Science 150, 893-899 (1965).
3. Reddi, A.H. & Huggins, C.B. Biochemical sequences in the transformation of normal fibroblasts in adolescent rat. Proc. Nat. Acad. Sci. USA 69, 1 601 -1605 (1972).
4. Reddi, A.H. Cell biology and biochemistry of endochondral bone development. Coll. Rel Res. 1, 209-226 (1981).
5. Reddi, A.H. Bone Morphogenetic Proteins: an unconventional approach to isolation of first mammalian morphogens. Cytokine Growth Factor Review 8, 11-20 (1997).
6. Dudley, A.T., Lyons, K.M. & Robertson, E.J. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes and Development 9, 2795-2807 (1995).
7. Luo, G. et al. BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning. Genes & Development 9, 2808-2820 (1995).
8. Paralkar, V.M., Weeks, B.S., Yu, Y.M., Kleinman, H.K. & Reddi, A.M. Recombinant human bone morphogenetic protein 2B (BMP-4) stimulator of PC12 Cell Differentiation: Potentiation and binding to type IV collagen, J. Cell Biol. 119, 1721-1728 (1992).
9. Savage, C., Das, P., Finelli, A.L. & Padget, R. Caenorhabditis elegans genes Sma-2, Smo-3, and Smo-4 define a conserved family of transforming growth factor-(pathway components. Proc. Nat. Acad. Sci. USA 93, 790-794 (1996).
10. Wrana, J. & Pawson, T. Mad about SMADs. Nature 388, 28-29 (1997)
11. Nakao, A. et al. TCF-(receptor-mediated signaling through Smad 2, Smad 3, and Smad-4. Embo J. (in press)
12. Hayashi, H. et al. The mad-related protein Smad-7 associates with the TGF-(receptor and functions as an antagonist of TGF-(signaling. Cell 89, 1165-1173 (1997).